Job Description
The Senior Director of Strategic Partnerships & Geographic Expansion is responsible for leading and executing Geographic expansion initiatives and managing key strategic alliances within international region for all CF and non-CF assets. This role requires a deep understanding of international market entry strategies, licensing and distribution partnerships, and cross-functional collaboration to drive growth in new geographies. The ideal candidate will have a strong background in business development, alliance management, and commercial strategy, with a proven track record of successfully navigating complex regulatory and market landscapes.
Key Responsibilities:
- Assess international partnership operating model sustainability considering upcoming launches in CF and non-CF pipeline, market potential and risks as well as revenue saving to vertex
- Partner with INPP on the prioritization of geographic expansion strategy and opportunities in new (non-CF) disease areas and to develop a detailed expansion strategy and tactics for new disease states to be aligned with executive leadership.
- Ensures appropriate operational execution of market expansion strategy for International
- Oversee Market Expansion plans for CF portfolio, facilitate evaluation of expansion opportunities, development of strategic plans and operational execution.
- Serve as the primary relationship owner for key strategic partnerships, ensuring alignment with business objectives and fostering long-term collaboration, in collaboration with commercial leads and country manager
- Oversee contract negotiations, milestone tracking, and governance structures to maximize the value of partnerships.
- Oversee development and implementation of partner performance metrics and governance frameworks to drive accountability and results.
- Collaborate with internal stakeholders, including commercial, regulatory, legal, and finance teams, to align expansion and partnership strategies with corporate goals.
- Manage directly the Business Systems Coordinator, CF Geographic expansion and alliance management team.
Key Requirements:
- Extensive experience in pharmaceutical business development, alliance management, or international commercial strategy
- Emerging markets capabilities/ knowledge
- Proven track record of leading geographic expansion initiatives, including market analysis, regulatory navigation, and commercial launch execution
- Strong negotiation and relationship management skills, with experience structuring and managing complex partnerships.
- Deep understanding of global pharmaceutical markets, regulatory requirements, and pricing and reimbursement dynamics
- Excellent leadership, communication, and stakeholder management abilities
- Strong understanding of the process to build new markets including expansion models, requirements and risks
- Experience working in a fast-paced matrixed organization
- Experience leading and aligning complex, multi-faceted, cross-functional, cross-geographic projects and teams
- Demonstrated ability to develop, evaluate and articulate complex business cases, including detailed financial projections
- Excellent communication skills
- Proven ability to interact with senior/executive leadership
- Demonstrated ability to translate detailed research & analysis into actionable commercial insights to inform organizational and business decisions for future expansion of International into new disease areas and geographies
- Proven ability in developing and communicating sound recommendations, even when there is ambiguity due to uncertainty and lack of validated assumptions.
Flex Designation:
Hybrid-Eligible Or On-Site Eligible
Flex Eligibility Status:
In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [email protected]
Vertex Pharmaceuticals Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Vertex Pharmaceuticals and has not been reviewed or approved by Vertex Pharmaceuticals.
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Parental & Family Support — Policies provide 12 weeks of 100% paid bonding leave for all U.S. parents with additional fully paid time for birth parents. Family-forming supports include adoption and surrogacy assistance, fertility options like IVF and egg cryopreservation, breast‑milk shipping, subsidized childcare, backup care, and a DCFSA match.
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Leave & Time Off Breadth — Time off includes roughly four weeks of vacation, 13 holidays, sick time, and two companywide shutdowns (summer and year‑end). Some roles also include flexible or unlimited time off and paid volunteer time.
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Retirement Support — Programs include a 401(k) plan with employer contributions and an employee stock purchase plan. Filings describe employer contributions occurring in company stock, supporting long‑term ownership.
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What We Do
Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious and life-threatening diseases. We discovered and developed the first medicines to treat the underlying cause of cystic fibrosis (CF), a rare, life-threatening genetic disease. In addition to clinical development programs in CF, Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases. Founded in 1989 in Cambridge, Massachusetts, our corporate headquarters is now located in Boston’s Innovation District, and our international headquarters is in London, United Kingdom. We currently employ approximately 3,500 people in the United States, Europe, Canada, Australia and Latin America with nearly two-thirds of our staff dedicated to research and development. Vertex is consistently recognized as one of the industry’s top places to work by Science Magazine, The Boston Globe, Boston Business Journal and the San Diego Business Journal. Our research and medicines have also received esteemed recognitions, including the Robert J. Beall Therapeutics Development Award, the French Prix Galien and the British Pharmacological Society awards.








