Heartflow is a medical technology company advancing the diagnosis and management of coronary artery disease, the #1 cause of death worldwide, using cutting-edge technology. The flagship product—an AI-driven, non-invasive cardiac test supported by the ACC/AHA Chest Pain Guidelines called the Heartflow FFRCT Analysis—provides a color-coded, 3D model of a patient’s coronary arteries indicating the impact blockages have on blood flow to the heart. Heartflow is the first AI-driven non-invasive integrated heart care solution across the CCTA pathway that helps clinicians identify stenoses in the coronary arteries (RoadMap™Analysis), assess coronary blood flow (FFRCT Analysis), and characterize and quantify coronary atherosclerosis (Plaque Analysis). Our pipeline of products is growing and so is our team; join us in helping to revolutionize precision heartcare.
Heartflow is a publicly traded company (HTFL) that has received international recognition for exceptional strides in healthcare innovation, is supported by medical societies around the world, cleared for use in the US, UK, Europe, Japan and Canada, and has been used for more than 500,000 patients worldwide.
As Senior Director, Program Management, you will lead cross-functional teams to drive the strategy, execution, and delivery of complex, high-stakes projects. You own the end-to-end program lifecycle — from initial scope and planning through final delivery — ensuring every cross-functional effort stays aligned with HeartFlow's long-term vision.
Responsibilities- Lead and direct multiple cross-functional program teams through the full lifecycle of complex initiatives, owning strategy, execution, and delivery.
- Define program strategy, timelines, and resource plans that meet business objectives, and drive teams to execute against them.
- Partner across functions to maintain alignment on priorities, dependencies, and decisions throughout each program.
- Build and implement risk management and contingency plans to keep programs on track.
- Communicate program status, priorities, and decisions clearly and consistently to team members and stakeholders at all levels, including senior leadership.
- Serve as the face of your program(s) to the executive leadership team, representing progress, risks, and outcomes.
- Lead resolution of issues and conflicts within and across teams, escalating when appropriate.
- Coach and develop team members, building a culture of accountability and continuous improvement.
- Bachelor's degree in Engineering, Business, or a related field; advanced degree a plus.
- 10+ years of program/project management experience, including 5+ years leading cross-functional teams in a matrixed organization.
- Experience managing complex, multi-workstream programs in a regulated industry (e.g., medical device or healthcare) strongly preferred.
- Track record of delivering complex programs on time and within budget.
- Program Management Expertise: Applies hybrid methodologies to lead the full lifecycle of complex, high-stakes programs.
- Influence Without Authority: Builds trust and drives cross-functional alignment across departments without direct reporting control.
- Executive Communication: Communicates clearly through verbal, written, and visual means, tailored to the audience — including senior leadership.
- Conflict Resolution: Navigates interpersonal and technical deadlocks to reach solutions that keep programs on track.
- Strategic Risk Management: Proactively identifies program dependencies and builds contingency plans before they impact timeline or budget.
- Executive Presence: Presents to senior leadership with confidence and clarity, translating technical milestones into business value.
- Adaptive Leadership: Pivots strategy quickly in response to shifting market conditions or organizational priorities.
A reasonable estimate of the yearly base compensation range is $265,000-$315,000, cash bonus, and equity. #LI-Hybrid
Skills Required
- Bachelor's degree in Engineering, Business, or related field
- Advanced degree
- 10+ years of program/project management experience
- 5+ years leading cross-functional teams in a matrixed organization
- Experience managing complex, multi-workstream programs in a regulated industry (medical device or healthcare)
- Track record of delivering complex programs on time and within budget
- Program management expertise using hybrid methodologies
- Demonstrated ability to influence without authority and drive cross-functional alignment
- Executive communication skills (verbal, written, visual)
- Conflict resolution and issue escalation skills
- Strategic risk identification and contingency planning
- Executive presence and experience presenting to senior leadership
- Adaptive leadership and ability to pivot strategy
What We Do
Heartflow is the global leader in AI-driven coronary artery disease (CAD) management, transforming how CAD — the world’s leading cause of death — is diagnosed and treated. Our advanced technology generates personalized, precision 3D heart models from a single CT scan, providing clinicians with the clarity and confidence to deliver earlier, more effective treatments — transforming CAD into a disease that can be managed for life. Heartflow One is the only complete, non-invasive, precision coronary care platform providing patient insights throughout the guideline-directed CCTA pathway. The AI-driven platform — including Roadmap™ Analysis, FFRCT Analysis and Plaque Analysis — is supported by the ACC/AHA Chest Pain Guideline and backed by more than 600 peer-reviewed publications. With over 400,000 patients treated, more than 1,400 leading institutions adopting our solution, and 99.5% of U.S. lives covered — Heartflow is redefining the standard of coronary care. We're a global company, with employees across the United States, Europe and Japan. Our headquarters are in Mountain View, California, with additional offices in California, Texas, the UK, and Japan. We believe CAD shouldn’t be a silent threat. By making it screenable, diagnosable, and manageable, we’re changing the story of CAD, empowering clinicians to save lives and giving patients more time for what matters most.
Why Work With Us
Join Us to Rewrite the Story of CAD.
