Job Description
Senior Director, Market Transformation
Job Summary
Vertex is seeking a Senior Director, Market Transformation to help position the company as a commercial leader in delivering life-changing medicines to patients through innovative capabilities, cutting-edge solutions, and strategic partnerships. This role will identify emerging market trends, bring external insights into the organization, and translate opportunities into scalable programs that increase awareness for our brands, improve patient access, and support business objectives.
The Senior Director will work cross-functionally to shape strategic decisions, accelerate innovation, and strengthen relationships with influential stakeholders across the healthcare ecosystem. This leader will play a critical role in improving patient access to our medicines while supporting sustainable growth across Vertex’s portfolio.
Key Responsibilities
- Monitor the external healthcare, market, and policy landscape to identify trends, risks, and opportunities relevant to Vertex brands and access strategies
- Provide actionable market insights that enable cross-functional teams to make informed brand, access, and commercialization decisions
- Support key product launches and portfolio optimization efforts by identifying market transformation opportunities that drive sustainable growth
- Evaluate and advance new solutions in areas such as AI, digital health, and alternative distribution models (e.g., CDS, telehealth)
- Design, develop, and activate innovative programs that drive awareness for our brands and improve patient access (e.g., develop business care, scout/select solutions, gain approval of programs)
- Rigorously evaluate the business value of proposed opportunities and capabilities using defined criteria, prioritizing programs with the most potential
- Establish and monitor adoption metrics and key KPIs, providing regular reporting to BU leadership on utilization and value realization
- Continuously assess operational efficiencies and innovative approaches that improve execution and patient outcomes
- Scale programs that demonstrate measurable impact and are ready for broader implementation across teams and partners
- Partner closely with Commercial, Market Access, Medical, Patient Support, Legal, Compliance, and other key functions to ensure alignment and execution
- Identify and cultivate relationships with new and influential external stakeholders, organizations, and partners to expand reach and enhance patient impact
- Lead with a strategic, patient-centered mindset while ensuring programs align with Vertex goals, standards, and compliance requirements
- Act as the primary liaison on BULT for market transformation, translating business needs into clear, prioritized opportunities and owning program execution within the BU
Qualifications
- Bachelor’s degree required; advanced degree preferred
- 12+ years of educational/work experience in biopharmaceuticals, healthcare strategy, commercial innovation, market access, consulting, or a related field Significant
- Proven ability to translate external market insights into strategic recommendations and business action
- Experience developing and implementing innovative healthcare solutions, partnerships, or patient access programs
- Strong understanding of the healthcare ecosystem, including market dynamics, access considerations, and stakeholder engagement
- Demonstrated success leading complex, cross-functional initiatives in a highly matrixed environment
- Strong executive presence, communication, and influence skills
- Ability to identify opportunities early, solve problems creatively, and drive execution with measurable impact
Leadership Competencies
- Strategic thinker with strong external orientation
- Innovative and solutions-focused
- Collaborative and highly effective in cross-functional environments
- Results-driven with strong operational discipline
- Patient-centered and mission-driven
- Skilled at building partnerships and influencing across internal and external stakeholders
Pay Range:
$232,000 - $348,000Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [email protected]
Skills Required
- Bachelor's degree
- Advanced degree
- 12+ years of experience in biopharmaceuticals, healthcare strategy, commercial innovation, market access, consulting, or related field
- Proven ability to translate external market insights into strategic recommendations and business action
- Experience developing and implementing innovative healthcare solutions, partnerships, or patient access programs
- Strong understanding of the healthcare ecosystem, including market dynamics, access considerations, and stakeholder engagement
- Demonstrated success leading complex, cross-functional initiatives in a highly matrixed environment
- Strong executive presence, communication, and influence skills
- Ability to identify opportunities early, solve problems creatively, and drive execution with measurable impact
- Experience evaluating and advancing solutions in AI, digital health, and alternative distribution models (e.g., CDS, telehealth)
Vertex Pharmaceuticals Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Vertex Pharmaceuticals and has not been reviewed or approved by Vertex Pharmaceuticals.
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Parental & Family Support — Policies provide 12 weeks of 100% paid bonding leave for all U.S. parents with additional fully paid time for birth parents. Family-forming supports include adoption and surrogacy assistance, fertility options like IVF and egg cryopreservation, breast‑milk shipping, subsidized childcare, backup care, and a DCFSA match.
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Leave & Time Off Breadth — Time off includes roughly four weeks of vacation, 13 holidays, sick time, and two companywide shutdowns (summer and year‑end). Some roles also include flexible or unlimited time off and paid volunteer time.
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Retirement Support — Programs include a 401(k) plan with employer contributions and an employee stock purchase plan. Filings describe employer contributions occurring in company stock, supporting long‑term ownership.
Vertex Pharmaceuticals Insights
What We Do
Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious and life-threatening diseases. We discovered and developed the first medicines to treat the underlying cause of cystic fibrosis (CF), a rare, life-threatening genetic disease. In addition to clinical development programs in CF, Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases. Founded in 1989 in Cambridge, Massachusetts, our corporate headquarters is now located in Boston’s Innovation District, and our international headquarters is in London, United Kingdom. We currently employ approximately 3,500 people in the United States, Europe, Canada, Australia and Latin America with nearly two-thirds of our staff dedicated to research and development. Vertex is consistently recognized as one of the industry’s top places to work by Science Magazine, The Boston Globe, Boston Business Journal and the San Diego Business Journal. Our research and medicines have also received esteemed recognitions, including the Robert J. Beall Therapeutics Development Award, the French Prix Galien and the British Pharmacological Society awards.
