Job Description
Company Overview:
Vertex is growing at a rapid pace with exciting opportunities for motivated professionals who want to contribute to our mission to invest in scientific innovation to create transformative medicines for people with serious diseases. Our Finance function plays a critical role in delivering on this mission by shaping strategy, enabling informed decision making, and providing deep business insight to support value creation across the enterprise.
General Summary:
The Senior Director of Commercial Finance is a senior leader within the US Commercial Finance organization and serves as the primary strategic business partner to the US Commercial Vice President and Business Unit Lead. This leader will partner with the BU Lead to develop options and guide resource allocation to balance growth and profitability. This highly visible role leads a team responsible for strategic financial management, revenue forecasting, analytics, investment management, and value creation across the business.
Key Duties and Responsibilities:
Strategic Leadership & Business Partnership
Serve as the finance business partner to the US Commercial Vice President and Business Unit Lead, leading strategic decision support and shaping long term commercial strategy and execution
Influence senior executives across Commercial, Medical, Human Resources, Global Finance, and Corporate functions to align financial plans with enterprise goals.
Anticipate market, competitive, and regulatory dynamics and provide actionable insights that guide commercial strategy and resource allocation.
Financial Strategy, Planning, and Performance Management
Lead the annual budget, long range planning process, and monthly forecasting cycles for the US Commercial BU, ensuring integration with global planning frameworks.
Oversee US revenue and operating expense management and drive analytical rigor and scenario planning to support portfolio optimization and launch readiness.
Identify value drivers and enterprise risks and develop innovative, data driven solutions to enable profitable and sustainable growth.
Leadership, Culture, and Team Development
Lead and develop a high performing team with capabilities aligned to Vertex leadership behaviors and culture.
Build a culture of accountability, operational excellence, and continuous improvement across the Commercial Finance organization.
Partner with HR on workforce planning and organizational design to support the growth of the US Commercial business.
Cross Functional Collaboration and Enterprise Influence
Partner with Global Commercial Finance, Accounting, Tax, and Investor Relations to strengthen financial systems, processes, and communication.
Drive alignment during key business cycles ensuring readiness for launches, lifecycle management, and competitive or market shifts.
Represent US Commercial Finance in enterprise forums providing strategic, data driven perspectives that influence business direction.
Knowledge and Skills:
Expert financial modeling, valuation, analytics, and scenario planning capabilities.
Strategic thinker with the ability to translate complex information into useful insights for senior leaders.
Exceptional executive communication and presentation skills.
Ability to lead through ambiguity, drive organizational change, and innovate in a fast paced environment.
Deep business acumen and understanding of the biotechnology market and commercial strategy.
Demonstrated ability to lead teams and foster an inclusive, development oriented culture.
Expertise with Excel and PowerPoint and working knowledge of Hyperion or similar planning tools.
Education and Experience:
- Bachelor’s degree in Finance, Accounting, or a related field required. Master of Business Administration or other advanced degree strongly preferred.
- Fifteen or more years of progressive finance experience in commercial, FP and A, or strategic roles including experience supporting senior executives or an equivalent combination of education and experience. Demonstrated success leading financial strategy in a complex and highly regulated environment.
- Extensive experience in drug development, commercialization, launch planning, pricing, reimbursement, and US market access.
- Proven ability to influence executives and lead enterprise level initiatives.
Pay Range:
$212,000 - $318,000Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation:
Hybrid-Eligible Or On-Site EligibleFlex Eligibility Status:
In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.
#LI-Hybrid
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [email protected]
Vertex Pharmaceuticals Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Vertex Pharmaceuticals and has not been reviewed or approved by Vertex Pharmaceuticals.
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Parental & Family Support — Policies provide 12 weeks of 100% paid bonding leave for all U.S. parents with additional fully paid time for birth parents. Family-forming supports include adoption and surrogacy assistance, fertility options like IVF and egg cryopreservation, breast‑milk shipping, subsidized childcare, backup care, and a DCFSA match.
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Leave & Time Off Breadth — Time off includes roughly four weeks of vacation, 13 holidays, sick time, and two companywide shutdowns (summer and year‑end). Some roles also include flexible or unlimited time off and paid volunteer time.
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Retirement Support — Programs include a 401(k) plan with employer contributions and an employee stock purchase plan. Filings describe employer contributions occurring in company stock, supporting long‑term ownership.
Vertex Pharmaceuticals Insights
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What We Do
Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious and life-threatening diseases. We discovered and developed the first medicines to treat the underlying cause of cystic fibrosis (CF), a rare, life-threatening genetic disease. In addition to clinical development programs in CF, Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases. Founded in 1989 in Cambridge, Massachusetts, our corporate headquarters is now located in Boston’s Innovation District, and our international headquarters is in London, United Kingdom. We currently employ approximately 3,500 people in the United States, Europe, Canada, Australia and Latin America with nearly two-thirds of our staff dedicated to research and development. Vertex is consistently recognized as one of the industry’s top places to work by Science Magazine, The Boston Globe, Boston Business Journal and the San Diego Business Journal. Our research and medicines have also received esteemed recognitions, including the Robert J. Beall Therapeutics Development Award, the French Prix Galien and the British Pharmacological Society awards.
