About the Role:
We are seeking an experienced biopharmaceutical strategy leader to lead high priority strategic initiatives and guide portfolio planning and cross-functional execution in a fast-moving drug development environment. This individual will work across our Product and Partnering organization, which includes portfolio strategy, internal R&D (Pioneering Medicines), and partnering units, to maximize the value of Flagship’s therapeutic platforms and assets. The ideal candidate will bring deep scientific grounding combined with strategic and operational leadership experience, ideally gained as an Engagement Manager, Principal or similar role at a consulting firm, along with practical exposure to biotech and/or pharma R&D.
This role reports to the Chief Operating Officer, Product & Partnering.
Key Responsibilities
- Lead high profile, cross-functional, business-critical strategic projects. Examples include new operating model designs to effectively scale R&D in an innovative environment; and accelerating drug development programs through use of AI and engagement with China.
- Partner with senior leaders across R&D, regulatory, commercial, finance, and BD to guide operating model, portfolio strategy, resource allocation, and milestone planning.
- Oversee and conduct high quality analytical work including competitive and market landscape analyses to inform long-term strategic direction and pipeline positioning.
- Communicate insights and recommendations to executive leadership through compelling, executive-ready presentations.
- Mentor and develop junior strategy and operations team members to elevate overall organizational capability.
Qualifications
Required
- Advanced degree in life sciences (PhD, MD, PharmD, or equivalent).
- 7–10+ years of experience in biopharma strategy, portfolio management, R&D strategy, or corporate development.
- Experience as a Principal or Project leader (or equivalent role) at BCG, McKinsey, Bain, or another top-tier strategy consulting firm, with demonstrated ability to lead complex engagements and manage client stakeholders.
- Demonstrated ability to structure ambiguous problems, build analytical frameworks, and translate insights into actionable strategic recommendations.
- Strong stakeholder management skills with experience influencing senior executives.
Preferred
- Experience working directly within a biotech or pharmaceutical organization in addition to consulting.
- Experience in portfolio governance, asset strategy, commercial assessment, or early R&D decision-making.
- Prior people leadership, including managing consultants or analysts.
Competencies
- Strategic and analytical thinking grounded in consulting rigor
- Ability to lead cross-functional teams and drive alignment
- Executive-level communication and presentation skills
- Strong scientific and business acumen
- High level of ownership, adaptability, and collaborative leadership style
- Ability to navigate ambiguity and prioritize effectively
LOCATION: Cambridge, MA
ABOUT FLAGSHIP PIONEERING
Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.
Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.
At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.
We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.
We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship.
Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.
#LI-TD1
The salary range for this role is $204,000 - $280,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Flagship Pioneering currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Flagship Pioneering's good faith estimate as of the date of publication and may be modified in the future.
Flagship Pioneering Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Flagship Pioneering and has not been reviewed or approved by Flagship Pioneering.
-
Fair & Transparent Compensation — Feedback suggests salary bands are visible for many Boston/Cambridge roles and pay is considered competitive for key scientific and leadership positions. Transparency in postings supports expectations that offers align with local biotech norms.
-
Healthcare Strength — Feedback suggests medical, dental, vision, disability, life insurance, HSA options, and mental-health coverage are comprehensive and well-regarded. Multiple items are employer-verified, reinforcing confidence in core health benefits.
-
Parental & Family Support — Feedback suggests maternity/paternity leave and family leave are offered at meaningful levels. These programs sit alongside paid holidays, sick days, and PTO to support family needs.
Flagship Pioneering Insights
Similar Jobs
What We Do
Flagship Pioneering conceives, creates, resources, and develops first-in-category life sciences companies to transform human health and sustainability. Since its launch in 2000, the firm has applied a unique, hypothesis-driven innovation process to originate and foster more than 100 scientific ventures, resulting in over $30 billion in aggregate value. To date, Flagship is backed by >$3 billion of aggregate capital commitments, of which over $1.5 billion has been deployed toward the founding and growth of its pioneering companies alongside >$10 billion of follow-on investments from other institutions. The current Flagship ecosystem includes Denali Therapeutics (NASDAQ: DNLI), Evelo Biosciences (NASDAQ: EVLO), Moderna Therapeutics (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), Seres Therapeutics (NASDAQ: MCRB), and Syros Pharmaceuticals (NASDAQ: SYRS).






