Senior Director, Commercial Supply Chain

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers.  The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:

Revolution Medicines is seeking a motivated individual to manage supply chain activities for its upcoming global commercial product launches.  Scope of responsibilities include but are not limited to commercial packaging, serialization, artwork management, demand and supply planning, inventory management, and global logistics and distribution.  This is an individual contributor role with team lead responsibilities, reporting to the head of Commercial Supply Chain.

Responsibilities:

• Manage supply chain deliverables and timeline to ensure successful product launches.

• Lead secondary packaging and labeling activities, including but not limited to packaging design, components sourcing, serialization, and validation.

• Lead design, generation, approval, and implementation of new and revised artwork and printed packaging components, in collaboration with RevMed’s marketing, regulatory, and quality groups, commercial packaging site, and other external stakeholders.

• Lead serialization implementation for new product and regional launches and manage day-to-day exceptions.

• Create and manage master data in ERP system to enable adequate inventory tracking, jurisdiction control, and global distribution.

• Define transport lanes for end-to-end supply chain and design appropriate shipping solutions. Manage shipping validation to support global regulatory filings.

• Enable adequate storage and shipping controls to meet products’ cold chain requirements and manage day-to-day temperature excursions.

• Devise and execute mock launch plan.

• Devise and execute rapid launch plan post regulatory approval.

• Own and execute change records for all supply chain activities.

• Align commercial demand and supply on a monthly basis and manage inventory. Partner with Business Operations Lead and commercial packaging site to ensure planned production is met.

• Define product and/or regional specific supply chain risks and devise mitigation plans.

• Establish and maintain business processes (BPs) and standard operating procedures (SOPs) to enable commercial secondary packaging, labeling, and distribution.

• Support implementation and manage Enterprise Resource Planning (ERP) system, if required.

 Required Skills, Experience, and Education:

• Sc. or M.Sc. with 18+ years of experience in pharmaceutical supply chain.

• Experience in commercial product launch preparation and execution.

• Experience in commercial secondary packaging and labeling, serialization, and validation.

• Experience in contract packaging and 3PL distribution operation.

• Experience in developing, negotiating, and executing manufacturing and service agreements.

• Experience managing both strategic and tactical/operational projects.

• Working knowledge of Good Manufacturing Practices (GMP) and Good Distribution Practices (GDP).

• Working knowledge of end-to-end pharmaceutical supply chain and demand/supply planning.

• Working knowledge of small molecule drug development and commercialization.

• Working knowledge of pharmaceutical commercial manufacturing, regulatory, and quality assurance.

• Strong negotiation skills.

• Solid project management, facilitation, and problem-solving skills.

• Solid organizational and time management skills.

• Effective, open, and transparent communication skills (verbal and written).

• Capable of working on multiple projects/tasks and able to meet timelines.

• Self-starter with a high level of comfort with ambiguity and complexity and the ability to multi-task while consistently delivering quality results.

• A team-oriented, progressive thinker who enjoys participating in an innovative and creative work environment.

Preferred Skills:

• APICS certification.

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