Job Description
General Summary:
The Senior Director, Clinical Pharmacology will serve as a Disease Area leader for Clinical Pharmacology. The Senior Director, Clinical Pharmacology will also manage the scientific functions and coordinate the activities of the Clinical Pharmacology function in collaboration with the other Disease Area leaders. The role’s responsibilities will include maintaining organizational processes across the group, influencing clinical program strategy, and integrating activities with other departments across the Global Research and Development organization, to help shape innovative and integrated clinical development plans. As a Disease Area leader, the Senior Director, Clinical Pharmacology will also direct Clinical Pharmacology efforts for small molecule and novel modality programs, such as gene editing, gene therapy, and cell therapy, in the Disease Area.
Key Duties and Responsibilities:
- Defines the scientific direction and directs the execution of clinical pharmacology plans for Disease Area programs
- Provides strategic operational leadership to the Clinical Pharmacology function in collaboration with the other Disease Area Leaders
- Manages a group of Clinical Pharmacologists at Director-level and below to set strategy, develop and execute Clinical Pharmacology plans and studies for Disease Area programs
- Directs Clinical Pharmacology efforts for small molecule and novel modality programs, such as gene editing, gene therapy, and cell therapy, in the Disease Area.
- As a people manager within the organization, may have financial accountabilities and human resource responsibilities for assigned staff.
Knowledge and Skills:
- Experience designing clinical pharmacology and pharmacometrics components of filing packages and associated clinical studies
- Experience with regulatory agency interactions including written responses and IND packages
- Experience with End of Phase 2 and NDA/MAA regulatory
- Support of drug development programs in all Phases including life-cycle management
- Experience leading cross-functional teams
- Superior communication skills
- Ability to solve complex problems while working in a matrix environment
- Academic or clinical postdoctoral training with significant publication history
Education and Experience:
- Ph.D. or Pharm D (or equivalent degree) in pharmacokinetics, pharmacometrics, clinical pharmacology or translational development and 15+ years of relevant post-doctoral employment experience, or
- Masters Degree (or equivalent degree) in pharmacokinetics, pharmacometrics, clinical pharmacology or translational development and 20+ years of relevant employment experience, or
- Typically requires 5 years of supervisory/management experience
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Pay Range:
$232,000 - $348,000Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation:
Hybrid-Eligible Or On-Site EligibleFlex Eligibility Status:
In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.
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Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [email protected]
Skills Required
- Ph.D. or Pharm D in pharmacokinetics, pharmacometrics, clinical pharmacology or translational development and 15+ years of relevant experience
- Masters Degree in pharmacokinetics, pharmacometrics, clinical pharmacology or translational development and 20+ years of relevant experience
- 5 years of supervisory/management experience
Vertex Pharmaceuticals Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Vertex Pharmaceuticals and has not been reviewed or approved by Vertex Pharmaceuticals.
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Parental & Family Support — Policies provide 12 weeks of 100% paid bonding leave for all U.S. parents with additional fully paid time for birth parents. Family-forming supports include adoption and surrogacy assistance, fertility options like IVF and egg cryopreservation, breast‑milk shipping, subsidized childcare, backup care, and a DCFSA match.
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Leave & Time Off Breadth — Time off includes roughly four weeks of vacation, 13 holidays, sick time, and two companywide shutdowns (summer and year‑end). Some roles also include flexible or unlimited time off and paid volunteer time.
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Retirement Support — Programs include a 401(k) plan with employer contributions and an employee stock purchase plan. Filings describe employer contributions occurring in company stock, supporting long‑term ownership.
Vertex Pharmaceuticals Insights
What We Do
Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious and life-threatening diseases. We discovered and developed the first medicines to treat the underlying cause of cystic fibrosis (CF), a rare, life-threatening genetic disease. In addition to clinical development programs in CF, Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases. Founded in 1989 in Cambridge, Massachusetts, our corporate headquarters is now located in Boston’s Innovation District, and our international headquarters is in London, United Kingdom. We currently employ approximately 3,500 people in the United States, Europe, Canada, Australia and Latin America with nearly two-thirds of our staff dedicated to research and development. Vertex is consistently recognized as one of the industry’s top places to work by Science Magazine, The Boston Globe, Boston Business Journal and the San Diego Business Journal. Our research and medicines have also received esteemed recognitions, including the Robert J. Beall Therapeutics Development Award, the French Prix Galien and the British Pharmacological Society awards.
