ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.
As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.
Senior Clinical Trial Manager
We are currently seeking a Senior Clinical Trial Manager to join our diverse and dynamic team at ICON. In this critical leadership role, you will oversee the operational delivery of clinical trials from study start-up through closeout, ensuring quality, compliance, and execution against study timelines and objectives.
As the clinical operations lead, you will work cross-functionally with sponsors, investigators, vendors, and internal stakeholders to drive successful study outcomes while identifying and mitigating risks throughout the trial lifecycle.
What you will be doing
- Lead the operational delivery of assigned clinical trials, ensuring milestones, timelines, budget expectations, and quality standards are achieved.
- Drive study start-up activities, site activation, enrollment strategies, and study execution through database lock.
- Provide oversight of study progress, monitoring activities, clinical metrics, and site performance.
- Develop and implement effective study oversight plans, monitoring strategies, and risk mitigation approaches.
- Identify operational challenges and proactively implement solutions to ensure successful study delivery.
- Build and maintain strong relationships with sponsors, investigators, vendors, and cross-functional stakeholders.
- Review study performance metrics and provide regular status updates and reporting.
- Support, mentor, and collaborate with Clinical Research Associates (CRAs) and other study team members.
- Ensure all clinical trial activities comply with protocol requirements, ICH-GCP guidelines, and applicable regulatory requirements.
Your Profile
- Bachelor's degree in Life Sciences, Health Sciences, Nursing, Pharmacy, or another relevant scientific discipline, or an equivalent combination of education and experience.
- Significant Clinical Trial Management experience within a CRO (preferred), pharmaceutical, or biotechnology environment.
- Demonstrated ability to successfully lead and deliver clinical studies from start-up through closeout.
- Strong understanding of clinical trial operations, ICH-GCP, and applicable regulatory requirements.
- Experience managing study timelines, budgets, vendors, and cross-functional stakeholders.
- Proven ability to identify risks, solve complex operational challenges, and drive study execution.
- Prior monitoring experience preferred.
- Experience managing global and/or complex clinical trials preferred.
- Ability to travel up to 20%.
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Employment with ICON is contingent upon having the legal right to work in the country where the role is based.
Rewards & Benefits
ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.
Benefits may include:
- Competitive base salary and performance related incentives
- Health and wellbeing programmes including medical, dental, and vision coverage where applicable
- Retirement and pension plans
- Life assurance and disability coverage
- Employee assistance programmes and wellbeing resources
- Learning and development opportunities through structured training and career pathways
Benefits may vary depending on role and location.
Visit our careers site to read more about the benefits ICON offers.
Inclusion and Accessibility
ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.
If you require reasonable accommodations during the recruitment process, please let us know or submit a request here.
Are you a current ICON Employee? Please click here to apply
Skills Required
- Bachelor's degree in Life Sciences, Health Sciences, Nursing, Pharmacy, or another relevant scientific discipline, or equivalent education and experience
- Significant clinical trial management experience in a CRO, pharmaceutical, or biotechnology environment
- Experience leading and delivering clinical studies from start-up through closeout
- Strong understanding of clinical trial operations, ICH-GCP, and applicable regulatory requirements
- Experience managing study timelines, budgets, vendors, and cross-functional stakeholders
- Ability to identify risks, solve complex operational challenges, and drive study execution
- Prior clinical trial monitoring experience
- Experience managing global and/or complex clinical trials
ICON plc Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about ICON plc and has not been reviewed or approved by ICON plc.
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Healthcare Strength — Benefits are described as comprehensive, with medical coverage and wellness initiatives highlighted. Larger sites are also associated with added wellness supports such as onsite fitness options and access to an employee assistance program.
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Leave & Time Off Breadth — Time-off and flexibility provisions are positioned as a meaningful part of the total package, including vacation/annual leave and flexible work scheduling. Flexibility is sometimes cited as helping offset long hours in certain roles.
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Retirement Support — Retirement and savings support is presented as a core component of the benefits package, including offerings such as pension arrangements in some locations and a U.S. 401(k) plan with company match. Financial planning resources are also emphasized as part of broader security benefits.
ICON plc Insights
What We Do
Since our foundation in Dublin, Ireland in 1990, our mission has been to help our clients to accelerate the development of drugs and devices that save lives and improve quality of life. We do this by delivering best in class information, solutions and performance, with an unyielding focus on quality at all times. We offer a full range of consulting, development and commercialisation services from a global network of offices in 53 countries. We focus our innovation on the factors that are critical to our clients – reducing time to market, reducing cost, and increasing quality – and our global team of experts has extensive experience in a broad range of therapeutic areas.
