The Role
Build and maintain high-performance TypeScript backend services and event-driven infrastructure. Design scalable APIs, integrate PostgreSQL/MySQL, AWS SQS, and Centrifugo, ensure reliability, security, and observability, optimize production systems, modernize legacy code, and own end-to-end feature delivery with strong testing, debugging, and performance tuning.
Summary Generated by Built In
Sequencing is building the interface between humanity and its DNA.
Using clinical-grade whole genome sequencing, AI, and a rapidly expanding ecosystem of genomic applications, we help people better understand themselves, their health, and their future through their DNA.
The human genome is one of the most valuable and underutilized resources in the world. Our mission is to transform the human genome into a lifelong source of personalized guidance and build the trusted home for every genome on Earth.
As the world’s largest direct-to-consumer whole genome sequencing platform, Sequencing is helping define the future of AI-powered personalized health.
We’re a profitable, venture-backed, fully remote company building category-defining products that help people better understand themselves through their DNA.
As a Senior Backend TypeScript Engineer you build and maintain the high performance backend services that power our core personalized health experiences. You work side by side with other senior engineers to build and grow scalable infrastructure APIs and event driven services. When you do this well people get fast reliable personalized health insights from their genome instead of slow or broken experiences.
The Impact
- Design build and maintain performant backend services in TypeScript that power our core personalized experiences.
- Build and grow scalable infrastructure APIs and event driven services that deliver data driven features to users.
- Support and optimize production ready backend systems so they stay fast and dependable under load.
- Integrate and manage services such as PostgreSQL MySQL AWS SQS and Centrifugo in the backend.
- Make systems reliable secure and observable so people can trust their DNA data is safe.
- Own and drive end to end feature development with a strong eye on user experience.
- Write clean reliable code with performance and maintainability in mind from the start.
- Champion clean code technical excellence and continuous improvement across the team.
- Debug test and performance tune across services to catch problems before users feel them.
- Maintain modernize and migrate legacy code so older systems keep up with new demand.
- Take ownership of complex problems and drive them to a clear working solution.
Dominant and Expressed Traits
- 5+ years of backend development experience.
- Expert with TypeScript and comfortable owning production backend services.
- Experience with functional programming.
- Deep hands on experience with PostgreSQL MySQL and service based architectures.
- Strong debugging testing and performance tuning skills.
- Able to work independently while collaborating closely with key teammates.
- Customer driven with a passion for building systems that deliver exceptional experiences.
- Nice to have familiarity with genomics health data or personalization systems startup or fast paced environments or Rust.
Skills Required
- 5+ years of backend development experience
- Expert with TypeScript and production backend services
- Experience with functional programming
- Deep hands-on experience with PostgreSQL and MySQL
- Experience with service-based / event-driven architectures
- Strong debugging, testing, and performance tuning skills
- Ability to work independently and collaborate closely with teammates
- Familiarity with genomics, health data, personalization systems, startup/fast-paced environments, or Rust
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The Company
What We Do
Sequencing.com is a genomics platform that provides clinical-grade whole genome sequencing, at-home DNA kits, and free lifetime DNA data storage. The company offers an app/report marketplace, AI-enabled interpretation, and personalized health, wellness, and ancestry reports produced from WGS data, with emphasis on privacy and ongoing updates to drive actionable insights for prevention and personalized care.








