At Weave, our mission is to evolve how therapeutic knowledge is captured, transformed, and communicated throughout drug development. We do this by equipping human experts with AI instruments to enable drugs to be brought to patients as rapidly, safely, and inexpensively as possible.
The Weave Platform streamlines regulatory workflows from start to finish by intelligently, creatively, and effectively infusing every step with AI. Together with our customers, Weave is designing and building the AI workbench for the entire therapeutic lifecycle.
We’re looking for a Senior Backend Engineer, reporting directly to the Backend Engineering Manager, that can navigate between data, AI, and backend systems. Stability, performance, and reliability of the AI system are the core responsibilities. You will be asked to develop novel solutions to customer problems, characterize the results, and deliver the solutions into production. You’ll be successful in this role if you can go from idea, to experiment, to testing, to production without getting lost or stuck at one of the steps. We care more about solving problems than using the latest buzz. We prefer simple, well-tested, stable solutions that are dependable, yet impressive.
What You'll Own- Understanding customer problems and translating that into simple solutions
- Working with Product and Design to quickly find solutions
- Writing performant, simple code. We run Django + Python + Postgres + Redis.
- Managing ongoing conceptual and technical complexity while delivering value on Product projects
- Integrating and optimizing LLM APIs (OpenAI, Anthropic) for document processing and AI features
What You’ll Bring
- 5+ years of Django in production with strong fundamentals in database optimization, caching, and system design
- Hands-on LLM experience — you've integrated OpenAI/Anthropic APIs directly, understand prompt engineering, and can debug model behavior
- SAAS product experience on highly scalable products
- Strong knowledge and experience with AWS deployment practices and concepts
- Product-focused mindset — you balance speed and quality, make pragmatic trade-offs, and ship solutions that solve customer problems
- Production ownership — comfortable with on-call, debugging live issues, and taking responsibility for the systems you build
- Low ego, high output — collaborative, adaptable, and focused on team success over individual heroics
- Bonus: Early-stage startup experience, regulated domain experience (healthcare/pharma), or real-time collaborative systems
🎯 The opportunity to work at a modern, cutting-edge healthcare technology company devoted to meaningful positive impact on human life. Collaboration, velocity, and customer obsession are our baseline, demonstrations of craftsmanship and ROI are celebrated.
🏆 Competitive salary ($175,000 - $225,000) and equity packages.
🧬 Comprehensive health, dental and vision insurance
🏝️ Take care of you and yours: generous PTO, parental leave, OneMedical, TalkSpace, Teladoc.
🚀 Career development opportunities within a company entering a growth phase.
🌎 Hybrid in San Francisco with in-office days Tues/Wed/Thurs and flexibility to work remote Mon/Fri.
Equal Opportunity Employer: We are committed to creating a diverse environment and are proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status.
This organization participates in e-Verify:
Notice of E-Verify Participation
Notice of Right to Work
Skills Required
- 5+ years of Django in production with strong fundamentals in database optimization, caching, and system design.
- Hands-on LLM experience integrating OpenAI/Anthropic APIs, prompt engineering, and debugging model behavior.
- Production experience with Python, Postgres, and Redis.
- Experience building highly scalable SaaS products.
- Strong knowledge and experience with AWS deployment practices and concepts.
- Production ownership experience — comfortable with on-call, debugging live issues, and taking system responsibility.
- Product-focused mindset: balance speed and quality and ship pragmatic solutions.
- Low ego, collaborative team orientation.
- Early-stage startup experience.
- Regulated domain experience (healthcare/pharma).
- Experience building real-time collaborative systems.
Weave Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Weave and has not been reviewed or approved by Weave.
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Healthcare Strength — Benefits include comprehensive medical, dental, and vision coverage, mental-health support, and 24/7 virtual care through services such as One Medical, Talkspace, and Teladoc. Wellness programs, FSAs, and mentions of gym reimbursement further reinforce a strong health focus.
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Leave & Time Off Breadth — Time off spans generous PTO, paid holidays and sick days, bereavement leave, flexible time off, and instances of company-wide winter closure. Family medical leave is also highlighted as part of the time-off mix.
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Parental & Family Support — Support includes paid parental leave and family medical leave, with some references to fertility benefits. These offerings signal family-friendly policies uncommon in many early-stage startups.
Weave Insights
What We Do
At Weave, we are building the backbone for modern drug development. Drug development teams deserve tools that match the pace and complexity of their science, and our AI-native platform is designed to support them at every step. We focus on regulatory workflows, helping biotech and pharma organizations bring clarity and speed to documentation so that therapies can move forward without unnecessary delays. We partner with scientists, clinicians, and regulatory professionals who are dedicated to advancing new medicines. By improving the processes behind regulatory documentation, we help reduce bottlenecks and free up teams to focus on what matters most: discovery, innovation, and patient impact. Our approach is human driven and technology powered. We believe that the right combination of expertise and innovation can transform how life sciences organizations operate, making the development of therapies more efficient and collaborative. Weave is a small but mighty team of scientists, engineers, and industry experts united by a mission to help life changing medicines reach patients faster. Our collective experience in biotechnology, software, and regulation allows us to understand the challenges of drug development and create solutions that have a real and lasting impact. We are committed to working side by side with our partners to move science forward and to build the foundation that drug development teams need today and tomorrow.
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