Senior Associate Scientist, Neuroscience Translational Discovery

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

The Neuroscience TRC is committed to the development of transformational therapeutics for patients with neurodegenerative, neuropsychiatric and neuromuscular diseases. A network of external partnerships paired with internal discovery of small molecules, biologics and genetic medicines supports our ambition to become leaders in neuroscience. Internal research focuses on causal human biology linking the immune system, protein clearance and synaptic mechanisms with nervous system disorders, applying human cells, AI, ML and high-throughput biology to identify and validate novel mechanisms.

Areas of interest include, but are not limited to, the identification of disease modifying and symptomatic therapies for neurodegenerative, neuropsychiatric, neuroinflammatory and neuromuscular diseases; approaches to modulate protein clearance and reduce or eliminate toxic protein production; emerging technologies (RNA, DNA targeting) that when matched to underlying causal human biology may deliver a precision medicine portfolio with a high probability of translational success. We emphasize identification of neuroimaging and fluid biomarkers to track disease progression, target engagement and therapeutic response in our discovery and clinical programs.

Position Summary:

The Neuroscience Thematic Research Center (Neuro TRC) leverages external collaborations and internal research to establish a diverse portfolio targeting unmet needs in neurodegenerative, neuropsychiatric, neuroinflammatory and neuromuscular, diseases.   The Senior Associate Scientist, Translational Discovery, in collaboration with other members of the Neuro TRC, undertakes design and delivery of translational data packages that enable rapid progression of drug candidates towards clinical proof-of-concept. This position is based in Cambridge, MA, and is primarily a laboratory-based role.

Position Responsibilities:

In the role as a Senior Associate Scientist within the Translational Discovery group, the ideal candidate will:

• Work closely with the team to develop target engagement and biomarker assays for assets in early development.

• Drive biomarker assay qualification with CROs.

• In collaboration with Global Biospecimen Inventory Management, manage TRC specimens for target engagement and biomarker development

• Prepare data packages to support target engagement and biomarker data inclusion for phase 1 studies.

• Work closely, in collaboration with in-house science teams, on study designs, data analyses, interpretation that support high priority neuro projects/programs.

• Draft and review internal project reports as needed; present scientific data at internal and external conferences.

Experience =

Basic Qualifications:

• Bachelor’s Degree

  • 4+ years of academic and / or industry experience

Or

• Master’s Degree

  • 2+ years of academic and / or industry experience

Preferred Qualifications:

• Hands on experience in immunoassay and molecular assays (ELISA, Meso-scale discovery, SIMOA, qPCR, dd-PCR, RNAseq, etc.).

• Experience in managing biorepositories

• Proven track record in designing, troubleshooting, analyzing and interpreting data from translational and experimental medicine type studies.

• Experience transferring assay to contract research organizations for analysis in multi-site clinical trials.

• Deep understanding of unmet need and clinical outcome measures used in studies focused on neurodegenerative disorders

• Excellent oral and written communication skills

• Ability to work both independently and as a well-integrated member of multidisciplinary drug development teams

#LI-Onsite

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [email protected]. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

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