Senior AI/ML Architect - AI Program

Posted Yesterday
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Rochester, MN, USA
In-Office
Senior level
Healthtech
The Role
Lead architectural design and delivery of scalable AI solutions for healthcare, focusing on foundation models, multimodal and vision-language systems, data architecture, model interpretability, deployment, and cross-functional integration. Provide technical leadership, mentorship, and consultative services across teams to ensure compliant, secure, and production-ready AI systems that improve patient outcomes.
Summary Generated by Built In

Senior AI/ML Architects at Mayo Clinic serve at the leading edge of data, systems, and computer sciences, embodying the convergence of technological expertise and visionary innovation. In our dynamic and collaborative environment, Senior AI/ML Architects are pivotal in transforming healthcare, advancing patient care through cutting-edge AI solutions. By joining our team, you will navigate the complexities of AI technologies, multimodal AI architectures, data architecture, and system integration, crafting scalable, impactful AI models and infrastructures that drive forward medical breakthroughs and improve patient outcomes. This includes guiding architectural decisions related to foundation models, vision-language systems, representation learning, model interpretability, and the integration of diverse healthcare data modalities.

As part of our dedicated team, you will work alongside world-class professionals, leveraging state-of-the-art resources to solve real-world challenges. Our commitment to excellence and innovation provides an unparalleled platform for professional growth and the opportunity to make significant contributions to the field of healthcare. If you are passionate about harnessing the power of AI to make a difference, we invite you to explore our AI/ML Architect job family, which includes AI/ML Architect, Senior AI/ML Architect, and Principal AI/ML Architect positions. Each role offers a unique opportunity to influence the future of healthcare technology and improve lives on a global scale.

Other Responsibilities May Include:
•   Providing strategic direction and technical leadership for complex AI Engineering initiatives.
•   Designing and implementing enterprise-wide AI models and solutions that address complex healthcare challenges, improving patient care and outcomes. This includes evaluating and guiding the use of foundation models, multimodal learning approaches, vision encoders, and AI architectures that leverage clinical text, medical imaging, genomic, and other healthcare data sources.
•   Collaborating with cross-functional teams, including data scientists, engineers, and healthcare professionals, to seamlessly integrate AI technologies into our systems.
•   Evaluating and recommending new technologies to enable continuous innovation across Mayo Clinic, including advances in multimodal AI, vision-language models, foundation models, representation learning, model interpretability, and emerging AI architectures relevant to healthcare.
•   Contributing to the development of scalable and efficient data architectures, ensuring the integrity and accessibility of healthcare data.
•   Participating in the entire lifecycle of AI solution development, from concept to deployment, including problem identification, system architecture design, implementation, and evaluation. Providing architectural guidance on model selection, multimodal fusion strategies, evaluation methodologies, explainability, scalability, and deployment considerations.
•   Leading the collaboration with cross-functional teams, including clinicians, translation engineers, software engineers, and product managers, to gather requirements, assess feasibility, define the scope, requirements, and deliverables of AI projects.
•   Providing consultative services to departments and divisions, offering insights and strategies to address complex business problems.
•   Evaluating and guiding architectural decisions for advanced AI systems, including multimodal foundation models, vision-language architectures, representation learning approaches, embedding strategies, and early-, mid-, and late-fusion methodologies for heterogeneous healthcare data.
•   Providing mentorship, guidance, and technical leadership to junior architects and engineers within the AI enablement team. May have supervisory responsibilities.

This is a full-time remote position within the United States. 

Mayo Clinic will not sponsor or transfer visas for this position including F1 OPT STEM.


Qualifications

Required Qualifications:
•   A master’s degree engineering, computer science, health science, or a related field with 10 years of experience, or a bachelor’s degree with 12 years of experience.
•   At least 10 years of experience applying AI and machine learning in production healthcare environments or similar highly regulated or technology focused industries, showing an acute understanding of healthcare technology.
•   Demonstrated leadership in managing large projects involving complex architectures, with a proven ability to navigate intricate project requirements and deliver successful outcomes.
•   Proficiency in fostering collaboration across diverse teams and effectively communicating complex technical concepts to non-technical stakeholders.
•   Proficiency in multiple programming languages, such as Python, Java, C++, JavaScript, etc.
•   Considerable experience with AI/ML frameworks (e.g., TensorFlow, PyTorch).
•   Experience using large language models as part of a solution.
•   Deep understanding of cloud computing platforms (GCP, AWS, Azure).
•   Rich understanding of data structures, algorithms, and Good Machine Learning Practices (GMLP)
•   A commitment to mentoring and training less-experienced team members, coupled with strong interpersonal, communication, and time management skills.
•   Demonstrated risk assessment and management capability, establishing robust testing strategies for technology solutions.
•   Deep understanding of data use and data security in healthcare.
•   Acute awareness of best practices in the data engineering, data science, AI Engineering, and  MLOps communities.
Preferred qualifications:
•   A PhD or other doctorate degree is preferred. 
•   Advanced AI, machine learning, and data analytics knowledge applicable to solution architecture and development, including multimodal AI, computer vision, foundation models, representation learning, and model evaluation methodologies.
•   Demonstrated experience developing and deploying machine learning systems in the cloud (e.g., Google Cloud, AWS, Microsoft Azure).
•   In-depth knowledge of healthcare domain, including clinical workflows, electronic health records (EHR), medical terminologies, regulatory requirements (e.g., HIPAA, GDPR), and industry standards (e.g., HL7, DICOM).
•   Understanding of regulatory standards and compliance frameworks, with the ability to effectively adapt these to different project environments.
•   Excellent communication, collaboration, and stakeholder management skills, with the ability to effectively engage with diverse stakeholders and translate complex technical concepts and results to non-technical audiences.
 

About Us
Why Mayo Clinic

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.

Benefits Highlights
  • Medical: Multiple plan options.
  • Dental: Delta Dental or reimbursement account for flexible coverage.
  • Vision: Affordable plan with national network.
  • Pre-Tax Savings: HSA and FSAs for eligible expenses.
  • Retirement: Competitive retirement package to secure your future.
About the Team
Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is. 

Equal Opportunity

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law".  Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.

Skills Required

  • Master's degree in engineering, computer science, health science, or related with 10 years experience, or bachelor's degree with 12 years experience
  • At least 10 years applying AI/ML in production healthcare or similarly regulated/technology-focused industries
  • Demonstrated leadership managing large projects involving complex architectures
  • Proficiency communicating complex technical concepts and collaborating across diverse teams
  • Proficiency in multiple programming languages (e.g., Python, Java, C++, JavaScript)
  • Considerable experience with AI/ML frameworks (e.g., TensorFlow, PyTorch)
  • Experience using large language models as part of a solution
  • Deep understanding of cloud computing platforms (GCP, AWS, Azure)
  • Strong knowledge of data structures, algorithms, and Good Machine Learning Practices (GMLP)
  • Commitment to mentoring and training less-experienced team members
  • Demonstrated risk assessment and management capability and establishing testing strategies
  • Deep understanding of data use and data security in healthcare
  • Awareness of best practices in data engineering, data science, AI engineering, and MLOps
  • May have supervisory responsibilities and provide technical leadership to junior staff
  • Experience evaluating and guiding use of foundation models, vision-language systems, representation learning, multimodal fusion strategies
  • In-depth knowledge of healthcare domain standards and formats (HL7, DICOM, EHR) and regulatory considerations
  • PhD or other doctorate degree
  • Advanced AI, ML, and data analytics knowledge, including multimodal AI, computer vision, foundation models, representation learning, and model evaluation methodologies
  • Demonstrated experience developing and deploying ML systems in the cloud (Google Cloud, AWS, Microsoft Azure)
  • Understanding of regulatory standards and compliance frameworks (e.g., HIPAA, GDPR) and ability to adapt to project environments
  • Excellent stakeholder management and ability to translate technical concepts to non-technical audiences

Mayo Clinic Compensation & Benefits Highlights

The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Mayo Clinic and has not been reviewed or approved by Mayo Clinic.

  • Retirement Support A no-cost pension plus an employer-matched 403(b)/401(k) is positioned as a standout differentiator, offering strong long-term financial security. Feedback suggests this retirement combination elevates overall total rewards even when base pay is moderate.
  • Healthcare Strength Expanded medical networks, enhanced fertility coverage, and employer absorption of a plan year’s premium increases point to robust healthcare offerings. Feedback suggests annual updates maintain breadth and competitiveness of coverage.
  • Parental & Family Support Adoption assistance, dependent scholarships, child and elder-care resources, and EAP services provide meaningful family-oriented support. Feedback suggests these programs add tangible value beyond salary alone.

Mayo Clinic Insights

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The Company
HQ: Rochester, MN
54,000 Employees

What We Do

Mayo Clinic is the first and largest integrated, not-for-profit medical group practice in the world. Doctors from every medical specialty work together to care for patients, joined by common systems and a philosophy of "the needs of the patient come first."​ More than 3,800 physicians and scientists and 50,900 allied health staff work at Mayo Clinic, which has sites in Rochester, Minn., Jacksonville, Fla., and Scottsdale/Phoenix, Ariz. Mayo Clinic also serves over 70 communities through Mayo Clinic Health System with locations in MN, IA, and WI. Collectively, these locations care for more than 1 million people each year.

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