At Weave, our mission is to evolve how therapeutic knowledge is captured, transformed, and communicated throughout drug development. We do this by equipping human experts with AI instruments to enable drugs to be brought to patients as rapidly, safely, and inexpensively as possible.
The Weave Platform streamlines regulatory workflows from start to finish by intelligently, creatively, and effectively infusing every step with AI. Together with our customers, Weave is designing and building the AI workbench for the entire therapeutic lifecycle.
We’re seeking a hands-on Senior AI Engineer who can bridge the gap between data and biomedical expertise while delivering robust backend code. Reporting to the Head of Applied AI, your primary focus will be building the LLM-facing components of our backend service, while ensuring the AI models consistently produce accurate, grounded, useful, and reliable outputs under real-world load.
The ideal candidate thrives in the full development cycle: taking concepts from initial conception through rigorous experimentation and testing, all the way to production deployment. You won't get lost in low-ROI side quests, but instead will maintain velocity with unwavering focus on the core value of your tasks.
We value pragmatic problem-solving over flashy technology and buzz words, robustly tested solutions over demoware. We're building solutions that actually work—simple, thoroughly tested, and rock-solid reliable. If you believe the best technology is the one that consistently delivers results, you'll fit right in.
What You'll Own- Writing production-ready backend code for LLM-facing components of our backend service
- Building automated evaluation systems for LLM-dependent code, including regression datasets, quality metrics, failure taxonomies, and release gates
- Designing and validating LLM-based solutions (prompts, context-construction pipelines, tool-calling workflows, structured outputs, and retrieval systems) and proving their effectiveness with real data and meaningful metrics
- Measuring and improving LLM solutions quality, grounding, consistency, latency, token usage, and cost
- Direct experience building, shipping and operating meaningful LLM-powered products or workflows in production
- Scientific or quantitative background in machine learning, statistics, computer science, biology, chemistry, or a related field; experience in biotech, pharmaceuticals, or another life-sciences setting is preferred
- Humble, hungry, and smart attitude
- Ability to move quickly while maintaining a high bar for correctness and reliability
- Clear technical judgment: able to explain trade-offs, prioritize high-value work, and stop low-ROI experimentation
- Bonus:
- History of working at early-stage, product-based startups (<100 people)
- Experience developing software in regulated or high-accountability environments
🎯 The opportunity to work at a modern, cutting-edge healthcare technology company devoted to meaningful positive impact on human life. Collaboration, velocity, and customer obsession are our baseline, demonstrations of craftsmanship and ROI are celebrated.
🏆 Competitive salary ($175,000 - $215,000) and equity packages.
🧬 Comprehensive health, dental and vision insurance
🏝️ Take care of you and yours: generous PTO, parental leave, OneMedical, TalkSpace, Teladoc.
🚀 Career development opportunities within a company entering a growth phase.
🌎 Hybrid in San Francisco with in-office days Tues/Wed/Thurs and flexibility to work remote Mon/Fri.
Equal Opportunity Employer: We are committed to creating a diverse environment and are proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status.
This organization participates in e-Verify:
Notice of E-Verify Participation
Notice of Right to Work
Skills Required
- Direct experience building, shipping, and operating LLM-powered products or workflows in production.
- Scientific or quantitative background in machine learning, statistics, computer science, biology, chemistry, or a related field.
- Experience writing production-ready backend code for LLM-facing components or backend services.
- Experience designing and validating LLM-based solutions: prompts, context-construction pipelines, tool-calling workflows, structured outputs, and retrieval systems.
- Experience building automated evaluation systems for LLM-dependent code, including regression datasets, quality metrics, failure taxonomies, and release gates.
- Ability to move quickly while maintaining a high bar for correctness, reliability, and technical judgment.
- Clear technical judgment and the ability to prioritize high-value work and stop low-ROI experimentation.
- Experience in biotech, pharmaceuticals, or another life-sciences setting.
- History of working at early-stage, product-based startups or experience developing software in regulated/high-accountability environments.
Weave Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Weave and has not been reviewed or approved by Weave.
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Healthcare Strength — Benefits include comprehensive medical, dental, and vision coverage, mental-health support, and 24/7 virtual care through services such as One Medical, Talkspace, and Teladoc. Wellness programs, FSAs, and mentions of gym reimbursement further reinforce a strong health focus.
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Leave & Time Off Breadth — Time off spans generous PTO, paid holidays and sick days, bereavement leave, flexible time off, and instances of company-wide winter closure. Family medical leave is also highlighted as part of the time-off mix.
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Parental & Family Support — Support includes paid parental leave and family medical leave, with some references to fertility benefits. These offerings signal family-friendly policies uncommon in many early-stage startups.
Weave Insights
What We Do
At Weave, we are building the backbone for modern drug development. Drug development teams deserve tools that match the pace and complexity of their science, and our AI-native platform is designed to support them at every step. We focus on regulatory workflows, helping biotech and pharma organizations bring clarity and speed to documentation so that therapies can move forward without unnecessary delays. We partner with scientists, clinicians, and regulatory professionals who are dedicated to advancing new medicines. By improving the processes behind regulatory documentation, we help reduce bottlenecks and free up teams to focus on what matters most: discovery, innovation, and patient impact. Our approach is human driven and technology powered. We believe that the right combination of expertise and innovation can transform how life sciences organizations operate, making the development of therapies more efficient and collaborative. Weave is a small but mighty team of scientists, engineers, and industry experts united by a mission to help life changing medicines reach patients faster. Our collective experience in biotechnology, software, and regulation allows us to understand the challenges of drug development and create solutions that have a real and lasting impact. We are committed to working side by side with our partners to move science forward and to build the foundation that drug development teams need today and tomorrow.
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