InterSystems is a global leader in healthcare data management and interoperability, providing mission-critical technology that powers hospitals, health systems, and national infrastructures worldwide. Our products underpin trusted healthcare and financial systems where performance, availability, and security are non-negotiable.
As a Senior Program Manager, you lead large-scale, complex, cross-functional initiatives across product, engineering, cloud, and AI. You operate across organizational boundaries, translating objectives aligned to corporate strategy into coordinated, measurable outcomes. You support and operationalize the security strategy across the portfolio, ensuring effective execution through structured programs.
Security and performance are horizontal capabilities across our stack. You partner with product, engineering, and architecture to maintain consistent execution across the portfolio.
Key Characteristics
- Thrives in high ambiguity, competing priorities
- Owns outcomes at a program level
- Connects strategy to execution (systems thinker)
- Influences without authority
- Execution-focused; manages complexity
- Communicates clearly across technical and business audiences
Key Responsibilities
- Program Strategy, Execution & Delivery
- Execute against existing program direction and strategic priorities, incorporating security and performance, and influencing future prioritization and execution
- Translate program strategy into execution plans across multiple teams and projects
- Lead concurrent projects to deliver program objectives
- Coordinate execution with program managers across cloud, database, interoperability, HealthShare, and AI-enabled systems
- Align scope, priorities, and dependencies to enable delivery
- Cross-Functional Leadership & Stakeholder Management
- Orchestrate work across product, engineering, architecture, compliance, and operations
- Serve as integration point for dependencies, timelines, and deliverables
- Manage senior stakeholders, including executive engagement
- Communicate progress, risks, and decisions to support leadership action
- Run structured updates and program reviews to maintain alignment
- Program Performance, Health & Continuous Improvement
- Monitor program performance and health against established KPIs, objectives, and milestones; contribute to KPI refinement
- Manage risks, issues, and dependencies; escalate when needed
- Maintain clear program visibility and enforce accountability
- Improve execution, coordination, and operational effectiveness
Qualifications
- Bachelor’s degree in Computer Science, Business, Engineering, or related field; advanced degree preferred
- 10+ years leading large-scale, complex, cross-functional programs
- Strong fundamentals in planning, scheduling, dependency and risk management
- Experience managing performance to KPIs and driving accountability
- Experience in cloud, healthcare, or enterprise technology environments preferred
- Proven ability to influence senior stakeholders without direct authority
- Strong communication and leadership skills
- PMP or equivalent certification a plus
We are an equal-opportunity employer and do not discriminate because of race, color, religion, sex, national origin, ancestry, marital status, veteran status, age, disability, sexual orientation or gender identity or expression or any other legally protected category. InterSystems is an E-Verify Employer in the United States.
InterSystems is providing a current good faith estimate of the anticipated base salary range for this position depending on a variety of factors including experience, education, skills, and performance.
Other compensation may include a discretionary annual variable target incentive.
The company also provides generous employee benefits including:
- Medical, vision, and dental insurance
- Short-term and long-term disability, and life insurance
- 401(k) Profit Sharing Contribution
- Paid Time Off and Holidays
- Parental Leave
- Tuition reimbursement
About InterSystems
InterSystems, a creative data technology provider, delivers a unified foundation for next-generation applications for healthcare, finance, manufacturing, and supply chain customers in more than 80 countries. Our data platforms solve interoperability, speed, and scalability problems for large organizations around the globe to unlock the power of data and allow people to perceive data in imaginative ways. Established in 1978, InterSystems is committed to excellence through its 24×7 support for customers and partners around the world. Privately held and headquartered in Boston, Massachusetts, InterSystems has 38 offices in 28 countries worldwide. For more information, please visit InterSystems.com.
Skills Required
- Bachelor's degree in Computer Science, Engineering, Cybersecurity, or related field
- Advanced degrees or certifications in product management or information security (e.g., CISSP, CISM, CCSK)
- 5+ years of experience in security engineering, product management, or related technical disciplines
- Strong understanding of database security, key management, encryption standards, and secure API design
- Familiarity with KMIP, OAuth, OIDC, and other interoperability protocols
- Experience integrating or governing AI/ML systems and MCP-based interfaces
- Understanding of cloud service models and cloud-native security controls
- Excellent communication and collaboration skills
- Demonstrated ability to deliver complex initiatives from concept to release
What the Team is Saying
InterSystems Compensation & Benefits Highlights
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Leave & Time Off Breadth — InterSystems states U.S. employees receive a minimum of 23 PTO days per year, plus paid holidays and sick time. Time‑off tiers by tenure are noted, yet the stated floor is generous.
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Healthcare Strength — The company lists comprehensive medical, dental, vision, FSAs/HSAs, mental‑health support, wellness programs, and some onsite fitness offerings. This breadth is emphasized across official materials and benefit summaries.
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Retirement Support — A 401(k) with employer contributions and a profit‑sharing component is offered, along with access to free financial advisors and planning tools for U.S. employees. This structure is positioned as competitive with common match programs.
InterSystems Insights
What We Do
InterSystems builds the software that makes complex systems work—reliably, securely, and at scale. For more than 45 years, we’ve been the information engine behind some of the world’s most mission-critical applications in healthcare, government, and business. Our data management, integration, and analytics technologies help organizations connect disparate systems, turn data into insight, and deliver better outcomes. From enabling interoperable healthcare and advancing clinical care, to powering national infrastructure and large-scale enterprise systems, our technology is used every day by millions of people in more than 80 countries. What sets InterSystems apart is not just what we build, but how we build it. We focus on long-term innovation, deep engineering excellence, and solving hard problems that truly matter. Our teams work closely with customers to tackle real-world challenges—often behind the scenes, but always at the heart of what keeps essential systems running. If you’re motivated by meaningful work, technical depth, and the opportunity to have a global impact, you’ll find it here.
Why Work With Us
Because we are a profitable, privately-held software company, we place our clients first in everything we do. You’ll work on meaningful, complex problems alongside deeply curious experts in a culture that values learning, ownership, and long-term growth—without the pressure of quarterly Wall Street demands.
Gallery
InterSystems Teams
InterSystems Offices
OnSite Workspace
InterSystems prioritizes in-person collaboration with majority on-site presence and some work from home flexibility that varies by region and office location.
