Scientist, Thymus-Based Therapeutics

California, US residents click here.

The Job Details are as follows:

Who We Are

We are the first publicly-traded biotech or pharmaceutical company to take the form of a public benefit corporation. Our public benefit purpose is to provide a brighter future for patients through the development of novel pharmaceutical therapies; and technologies that expand the availability of transplantable organs.

United Therapeutics (Nasdaq: UTHR) seeks to travel down the corridors of indifference to develop treatments for rare, deadly diseases. We were founded in 1996 by a family seeking a cure for their daughter’s pulmonary arterial hypertension (PAH). Today, we have six FDA-approved therapies that treat PAH, pulmonary hypertension associated with interstitial lung disease (PH-ILD) and neuroblastoma, a rare pediatric cancer. Our near-term pipeline seeks to develop additional therapies for PAH and pulmonary fibrosis (PF).

The cure for end-stage life-threatening diseases like PAH, PH-ILD, PF, and many others is an organ transplant, but only a small percentage of donated organs are available to address the vast need. For this reason, we are working to create manufactured organs to address the shortage of kidneys, hearts, lungs, and livers available for transplant. We believe an unlimited supply of tolerable, transplantable organs will eliminate the transplant waiting list and cure end-stage organ diseases for which transplant is not currently an option.

Who You Are

Do you want to be involved at the start of a brand-new program and contribute to scientific advancements? The Scientist, Thymus‑based Therapeutics (Preclinical & Translational Research) is responsible for performing preclinical and translational research, contributing to the establishment of a new research group and laboratory facility, and making direct contributions to the preclinical development pipeline through the advancement of in vitro and in vivo immunology platforms.

• Independently plan, execute, and analyze experiments in human thymus and T cell biology, including human primary cell culture, cell isolation assays, and in vitro T cell functional assays
• Perform multi-parameter flow cytometry and analysis
• Perform immunofluorescence tissue staining, imaging, and quantitative analysis
• Contribute to the planning, execution, and data analysis of humanized mouse models for preclinical evaluation
• Set up and help manage new lab spaces, including equipment organization, workflow development, and establishment of standard operating procedures
• Coordinate effectively with external vendors, animal care facilities, and Contract Research Organizations (CROs) to support in vivo studies and data generation
• Maintain detailed experimental records, analyze complex datasets, and present findings to the team
• Actively contribute to building a collaborative, high-performing research group in a dynamic startup culture

Minimum Requirements

• 2+ years of relevant postdoctoral or industry experience with a Doctor in Philosophy (PhD) in immunology, biomedical sciences, experimental medicine, or a closely related field
• Strong hands-on experience with human primary cell culture and sterile techniques
• Proficiency in flow cytometry (panel design, acquisition, and data analysis)
• Experience with cell isolation assays from human samples
• Hands-on experience with immunofluorescence tissue staining, imaging, and analysis
• Proven ability to work independently with minimal supervision, including designing, planning, executing, and troubleshooting experiments
• Excellent experimental planning and strong time management skills to deliver on project timelines
• Strong team player with excellent communication and collaboration skills
• Highly organized, detail-oriented, and proactive
• Learning and contributing to preclinical models and translational research
• Enthusiasm for working in a fast-paced, startup-like environment and helping establish a new research laboratory and team

Preferred Qualifications

• Experience planning and analyzing data from humanized mouse models
• Direct experience working with thymus and T cell platforms

Job Location

This role is located 100% onsite in Vancouver, British Columbia.

At United Therapeutics, our mission and vision are one. We use our enthusiasm, creativity, and persistence to innovate for the unmet medical needs of our patients and to benefit our other stakeholders. We are bold and unconventional. We have fun, we do good.

United Therapeutics is an equal opportunity employer committed to diversity and inclusion. We welcome and encourage applications from all qualified applicants.  Accommodations for persons with disabilities required during the recruitment process are available upon request.