Scientist/Sr. Scientist, Mechanistic Pharmacology

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Boston, MA, USA
In-Office
Biotech
The Role

About Superluminal Medicines:

Superluminal Medicines is a generative biology and chemistry company revolutionizing the speed and accuracy of how small molecule medicines are created. The Company’s platform aims to create candidate-ready compounds with unprecedented speed using a combination of deep biology, computational and medicinal chemistry, machine learning, and proprietary big data infrastructure. We are expanding the team of talented scientists who seek to build the future of small molecule drug discovery with creativity and innovation.

About the role: 

Superluminal Medicines is seeking a highly motivated and collaborative Scientist / Sr Scientist with experience in drug discovery and GPCR pharmacology to join their growing and dynamic Biology team and foster the discovery of new medicines. The company is a target and biology-first drug discovery organization that applies artificial intelligence and machine learning (AI/ML) methods to common drug development bottlenecks, while paying close attention to the seamless integration of biology, chemistry, and computation. This is a unique opportunity to build and grow a fruitful career with the company, apply your biology expertise to solve real world problems, advance the state of the practice of drug discovery and development, address unmet healthcare needs, and help patients worldwide.
Key responsibilities: 

  • Provide robust biology support for Superluminal Medicines’s research programs.
  • Think critically through target biology and formulate experimental plans to guide project trajectory.
  • Strategize and conduct cell biology experiments to support program enablement, drug discovery workflows, and mechanism of action evaluations.
  • Demonstrate a high level of initiative and discipline to execute experiments following established procedures and make suggestions to improve experimental design.
  • Interpret and effectively communicate results to interdisciplinary teams composed of chemists, computational biologists, and machine learning scientists in an environment that highly values scientific integrity and quality. 
  • Advance external collaborations and outsourced studies.
  • Prepare technical reports to support regulatory submissions.
  • Ensure compliance with company established practices and procedures, including those related to laboratory notebooks, computer files, quality and regulatory guidelines, and safety.

Qualifications & Skills

  • Ph.D. in Biochemistry, Biology, Pharmacology, or a related discipline with 1-5 years of experience supporting drug discovery programs.
  • Competency as the biology lead of an agile team that supports fast implementation and rapid decision making while maintaining a high level of coordination between internal and external parties.
  • Theoretical understanding of GPCRs, small molecule pharmacology, cellular signaling pathways, and lead discovery and optimization practices.
  • Technical proficiency in cellular assays and the ability to provide high quality in vitro results.
  • Ability to strategize and implement cellular mechanism of action investigations to build an understanding of the molecular pharmacology for key chemical equity.
  • Outstanding laboratory techniques to support cell culture and cell-based assays.
  • Enthusiasm in mastering the use of complex laboratory instrumentation and related software related to compound handling, cell-based assays, and database archiving.
  • Commitment to fostering collaborations across interdisciplinary teams and managing external partners.

Equal Opportunity Statement:

Superluminal Medicines is an Equal Opportunity Employer committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status.

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The Company
HQ: Boston, Massachusetts
24 Employees

What We Do

Superluminal Medicines is a Boston-based generative biology and chemistry company developing a differentiated pipeline and revolutionizing the speed and accuracy of how medicine is created. Our platform creates candidate-ready compounds with unprecedented speed using a comprehensive combination of deep biology and chemistry expertise, machine learning, and proprietary big data infrastructure. The predict-design-test architecture accurately models protein shapes and designs highly selective compounds to target the precise structural change for therapeutic effect. Our discovery engine is powered by an industry-leading, pharmacokinetic and toxicology in silico prediction capability. With a lead program candidate expected in the near term, our proprietary pipeline validates our platform with initial programs focused on high-value GPCR targets. We’re pleased to be backed by a strong network of investors including RA Capital Management, Insight Partners, NVentures, Catalio Capital Management, Eli Lilly and Company, Gaingels, and Cooley LLP.

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