Scientist, Probe Design

Posted 10 Days Ago
Be an Early Applicant
Newark, CA, USA
In-Office
89K-147K Annually
Senior level
Biotech
The Role
The Scientist, Probe Design will develop and optimize RNAscope probes, support customer needs, and collaborate with teams to ensure excellence in scientific consultation and product training.
Summary Generated by Built In

By joining Bio-Techne, you’ll join a company with a powerful and positive purpose of enabling cutting-edge research in Life Sciences and Clinical Diagnostics. Bio-Techne, and all of its brands, provides tools for researchers to further treat and prevent disease worldwide.

Pay Range:

$89,300.00 - $146,900.00

Advanced Cell Diagnostics, Inc. (ACD) is a leader in the field of molecular pathology and tissue-based diagnostics. Our core RNAscope® technology is the world’s first multiplex fluorescent and chromogenic in situ hybridization platform capable of detecting and quantifying RNA biomarkers in situ at single molecule sensitivity. RNAscope® is an ideal platform for developing the next generation of tissue-based companion diagnostics. We are committed to continued innovation to bridge the gap between basic research and clinical medicine to fulfill the promise of personalized medicine.
The Scientist, Probe Design is a key member of the R&D team. The Scientist will work within a highly dynamic group to develop and optimize new probe products based on our RNAscope® technology and work closely with our commercial team to identify and support customer needs.
Responsibilities

  • Design made-to-order RNAscope probes for target sequences using proprietary software
  • Answer technical inquiries related to design of target probes & submission of New Probe Requests (NPR)
  • Review NPR forms for accurate and efficient probe designs
  • Utilize Linux command-line tools for sequence alignments (BLAST/BLAT), probe selection, specificity
  • Provide probe product training and troubleshooting for Advanced Cell Diagnostics scientific probe product lines via phone and email
  • Act as primary contact for customers regarding technical issues, as well as providing scientific consultation for research use only inquiries
  • Collaborate with Commercial and Marketing teams to meet the needs of customers
  • Ensure customer service excellence and guaranteed response times by actively monitoring SalesForce queue, inbox, phone calls, and ensuring all issues are resolved in a timely and comprehensive manner
  • Contribute to ongoing new product development and introduction with R&D teams in a laboratory environment
  • Contribute to the ongoing development of the Probe Design team's knowledgebase
  • Present scientific and product updates to customers and internal teams

Qualifications
Education:

  • PhD with 4+ years of research experience in molecular biology, bioinformatics computational biology or a closely related field

Skills:

  • In-depth knowledge of genes and sequences, RNA biology
  • Familiarity with standard bioinformatics tools (Python, R, or equivalent), and a programming language (C/C++, Java)
  • Experience in commonly used biological databases and bioinformatics software tools
  • Ability to work within multi-disciplinary team of computational biologists, molecular biologists, imaging software scientists, biochemists and others
  • Post-graduate experience with experimental design, cell and molecular techniques
  • Must be very adept at diagnosing, troubleshooting and solving complex technical problems with a variety of biological assays
  • Highly self-directed, conscientious, articulate, and possesses excellent presentation and teaching skills

Experience:

  • 2yr+ of experience in Biotech/Biopharma R&D
  • 2yr+ of experience with Linux, Python, Perl or other programming languages
  • 2yr+ of experience with next-generation sequencing platforms or sequencing tools (genomic/epigenomic/transcriptomic)
  • Prior experience in probe design across multiple species
  • Experience in biological sequence analysis tasks such as database searches and multiple sequence alignment tools
  • Committed to total customer satisfaction with outstanding interpersonal skills and professionalism
  • Customer-facing experience with a strong scientific capacity

Working Conditions:

  • Ability to travel ~10% of time
  • Work is performed in office settings.
  • Regular use of computers.
  • Work may occasionally require extended hours to meet project deadlines.

Physical Requirements:

  • Prolonged periods of sitting or standing at a computer.

Why Join Bio-Techne:

  • We offer competitive insurance benefits starting on day one: medical, dental, vision, life, short-term disability, long-term disability, pet, and legal and ID shield.
  • We invest in our employees’ financial futures through 401k plans, an employee stock purchase plan (ESPP), Health Saving Account (HSA), Flexible Spending Account (FSA), and Dependent Care FSA.
  • We empower our employees develop their careers through mentorship, promotional opportunities, training and development, tuition reimbursement, internship programs, and more.
  • We offer employee resource groups, volunteer paid time off, employee events, and charity drives to build a culture of caring and belonging. 
  • We offer an accrued leave policy with paid holidays, paid time off, and paid parental leave.
  • We foster a culture of empowerment and innovation, where employees feel valued and encouraged to bring their new ideas to the table.

Bio-Techne is an E-Verify Employer in the United States.

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.

To protect the interests of all, Bio-Techne will not accept unsolicited resumes from any source other than a candidate application. Any unsolicited resumes sent to Bio-Techne will be considered Bio-Techne property.

Skills Required

  • PhD with 4+ years of research experience in molecular biology, bioinformatics, computational biology, or a closely related field
  • In-depth knowledge of genes and sequences, RNA biology
  • Familiarity with standard bioinformatics tools (Python, R, or equivalent)
  • Experience in commonly used biological databases and bioinformatics software
  • Ability to work within a multidisciplinary team
  • 2+ years of experience in Biotech/Biopharma R&D
  • 2+ years of experience with Linux, Python, Perl or other programming languages
  • 2+ years of experience with next-generation sequencing platforms
  • Prior experience in probe design across multiple species
  • Experience in biological sequence analysis tasks

Bio-Techne Compensation & Benefits Highlights

The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Bio-Techne and has not been reviewed or approved by Bio-Techne.

  • Healthcare Strength Medical and dental coverage are often regarded as strong, with core health benefits broadly available across U.S. roles. Day-one eligibility and comprehensive options are described as a relative bright spot even when pay sentiment is mixed.
  • Leave & Time Off Breadth PTO, paid holidays, paid parental leave, and volunteer time are emphasized alongside flexible scheduling. Work-life balance elements are seen as strengths relative to base-pay concerns.
  • Strong & Reliable Incentives Quarterly or semi-annual bonuses and eligibility for annual cash incentives add meaningful upside for many salaried roles. Structured plans such as a Management Incentive Plan reinforce predictability of variable pay.

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The Company
HQ: Minneapolis, MN
2,512 Employees
Year Founded: 1981

What We Do

Bio-Techne Corporation (NASDAQ: TECH) is a leading developer and manufacturer of high-quality purified proteins and reagent solutions - notably cytokines and growth factors, antibodies, immunoassays, biologically active small molecule compounds, tissue culture reagents, and cell and gene therapy workflow solutions including T-Cell activation technologies. Bio-Techne’s portfolio also includes protein analysis solutions, sold under the ProteinSimple brand name, that offer researchers efficient and streamlined options for automated Western blot and multiplexed ELISA workflow. These reagent and protein analysis solutions are sold to biomedical researchers, as well as clinical research laboratories, and constitute the Protein Sciences Segment. Bio-Techne also develops and manufactures diagnostic products including FDA-regulated controls, calibrators, blood gas and clinical chemistry controls, and other reagents for OEM and clinical customers. Bio-Techne’s genomic tools include advanced tissue-based in situ hybridization assays (ISH) for research and clinical use, sold under the ACD brand, as well as a portfolio of clinical molecular diagnostic oncology assays including the ExoDx®Prostate (IntelliScore) test (EPI) for prostate cancer diagnosis. These diagnostic and genomic products comprise Bio-Techne’s Diagnostics and Genomics Segment. Bio-Techne products are integral components of scientific investigations into biological processes and molecular diagnostics, revealing the nature, diagnosis, etiology and progression of specific diseases. They aid in drug discovery efforts and provide the means for accurate clinical tests and diagnoses. With thousands of products in its portfolio, Bio-Techne generated approximately $714 million in net sales in fiscal 2019 and has over 2,200 employees worldwide.

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