Scientist I (Biologics Drug Product Development)

Posted 8 Days Ago
Be an Early Applicant
Irvine, CA, USA
In-Office
112K-143K Annually
Senior level
Healthtech • Pharmaceutical
The Role
Support formulation and drug product process development for protein biologics (neurotoxins) across sterile liquids, lyophilized, and pre-filled dosage forms; manufacture formulation batches, conduct clinical in-use studies, generate and present formulation data, and prepare technical reports following GMP/GLP.
Summary Generated by Built In
Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.

Job Description

Key Responsibilities

  • Support formulation development of protein biologics from early development (pre-clinical/First-In-Human candidates) through commercialization, with a specific focus on neurotoxins for therapeutics & aesthetic use.  
  • Execute formulation composition & drug product process development studies for sterile liquids, lyophilized, & pre-filled dosage forms.
  • Manufacture drug product formulation batches for evaluating formulation stability & /or to support animal studies.
  • Conduct clinical in-use studies to guide dose solution administration.
  • Generate high-quality data based on sound scientific principles & prepare formulation data summaries, technical reports, & scientific presentations.

Qualifications

Education & Experience

Must have BS in pharmacy, chemical or biomedical engineering, chemistry, or biology & 5 years of experience as a scientist working in  biologics &/or drug product development. Of experience required, must have 5 years: (i) performing CMC development in drug &/or protein formulation, drug delivery, or analytical functions; (ii) planning & implementing manufacturing process development for biologics &/or various drug products; (iii) applying analytical tools & techniques used for drug &/or protein characterization &  stability including: HPLC, spectroscopy, HIAC, MFI, DLS, ELISA, & Karl Fisher; (iv) executing &  troubleshoot experiments through rational & critical thinking; (v) developing drug product manufacture processes & lyophilization cycles; (vi) executing & interpreting experiments for  formulation & process development; (vii) applying GMP/ GLP principles to all aspects of work;  & (viii) working with internal & external cross functional teams.  

Alternatively, would accept MS in pharmacy, chemical or biomedical engineering, chemistry, or biology & 6 months of experience as a scientist working in biologics &/or  drug product development. Of experience required, must have 6 months in each of (i), (iii), (iv), (vi), (vii) & (viii).  For points (ii) & (v), would accept graduate level coursework (theoretical understanding) as an alternative.

Work experience may be gained concurrently. Employer will accept combination of education, training & work experience.

Additional Information

Salary Range: $112,098.26 - $142,500.00 per year.

Apply online at https://careers.abbvie.com/en or send resume to [email protected]. Refer to Req ID: REF49788R

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We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.   This job is eligible to participate in our short-term and long-term incentive programs.

AbbVie is committed to operating with integrity, driving innovation, transforming lives, serving our community, and embracing diversity and inclusion. It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled. 

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

Skills Required

  • BS in pharmacy, chemical or biomedical engineering, chemistry, or biology with 5 years experience in biologics and/or drug product development
  • MS in pharmacy, chemical or biomedical engineering, chemistry, or biology with 6 months experience in biologics and/or drug product development (alternative to BS+5yrs)
  • Experience performing CMC development in drug and/or protein formulation, drug delivery, or analytical functions
  • Experience planning and implementing manufacturing process development for biologics and/or drug products (or graduate coursework for MS alternative)
  • Experience applying analytical tools and techniques for protein characterization and stability including HPLC, spectroscopy, HIAC, MFI, DLS, ELISA, and Karl Fisher
  • Ability to execute and troubleshoot experiments using rational and critical thinking
  • Experience developing drug product manufacture processes and lyophilization cycles (or graduate coursework for MS alternative)
  • Experience executing and interpreting experiments for formulation and process development
  • Knowledge and application of GMP and GLP principles to all aspects of work
  • Experience working with internal and external cross-functional teams

AbbVie Compensation & Benefits Highlights

The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about AbbVie and has not been reviewed or approved by AbbVie.

  • Retirement Support 401(k) contributions include a dollar-for-dollar match up to 6% plus an additional annual company contribution tied to age and service. Company-paid life insurance and other financial protections further strengthen long-term security.
  • Parental & Family Support Paid leave programs include up to 12 weeks at 100% for parental leave and separate paid caregiver leave, with eligibility after six months where noted. Adoption and surrogacy reimbursements and family-building resources add further support.
  • Healthcare Strength Health coverage begins on day one with medical, dental, vision, mental health, and prescription benefits, and preventive care covered at 100%. Options such as HSAs/FSAs and coverage for spouses/domestic partners and children up to age 26 broaden accessibility.

AbbVie Insights

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The Company
HQ: Chicago, IL
50,000 Employees
Year Founded: 2013

What We Do

AbbVie is a global biopharmaceutical company focused on creating medicines and solutions that put impact first — for patients, communities, and our world. We aim to address complex health issues and enhance people's lives through our core therapeutic areas: immunology, oncology, neuroscience, eye care, aesthetics and other areas of unmet need.

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