Scientist, Downstream Process Development

Advancing medicine to save lives. Together. 

Thanks to many decades of experience and our passion for what we do, we make an essential contribution to the global availability of biopharmaceuticals, especially for patients with rare and serious diseases.  

Rentschler Biopharma SE is a leading contract development and manufacturing organization (CDMO) focused exclusively on client projects. We offer customized full-service solutions for bioprocess development and the production of complex biopharmaceuticals. As a German family-owned company with an international footprint and global reach, we combine experts, expertise and years of experience to develop best-in-class solutions – together with our clients.

Rentschler Biopharma has approximately 1,400 employees and is headquartered in Laupheim, Germany, with a site in Milford, MA, USA. In 2024, we joined the United Nations Global Compact, underlining our commitment to sustainability.  

As an independent family-owned company, we live by the motto: Many hands, many minds - ONE TEAM! Open, respectful cooperation characterizes our working environment, where quality awareness, diligence and responsibility are our top priorities. With all the diversity of our talents in the Rentschler team, we pursue one vision together: advancing medicine to save lives. 

Duties and Responsibilities

• Assist in the development of scale-able and robust downstream processes including process characterization, and/or technology transfer leading to clinical and commercial GMP manufacturing for multiple client projects meeting the project deliverables
• Help design experiments related to development, optimization, scale-up of all steps in a monoclonal antibody and bispecific antibody purification process and viral clearance study, execute studies together with junior members
• Identify, evaluate, and implement new and existing technologies to improve process efficiency, control, and understanding
• Ability to work in a team environment
• Apply DOE and other advanced statistical techniques to design experiments related to process characterization
• Author high-quality documents, including technical reports, SOPs, and experimental protocols

Qualifications

• Bachelor’s degree in STEM with:
  • 3+ years of hands-on experience
  • Masters degree with 1+ year of hands-on experience
• Solid theoretical knowledge and hands-on experience in protein purification and analytical characterization
• Hands-on experience in protein purification and analytical characterization
• Hands-on experience with purification unit operations including filtration, different mode chromatography, UF/DF, AKTA, UNICORN, centrifugation
• Advanced ability with Microsoft Office (Word, Excel, and PowerPoint)
• Ability to support MFG floor activities when needed
• Ability to adapt to change priorities of the business

 Working Conditions   

• Laboratory environment working with chemical reagents and analytical equipment
• Personal Protective Equipment must be worn as required
• Normal office working conditions: computer, phone, files, fax, copier
• Will interact with other people
• Pace may be fast and job completion demands may be high

Physical Requirements

• Frequent lifting up to 10 lbs
• Frequent standing/walking to work in lab environment for extended periods
• Frequent sitting for extended periods to use computer