Scientist 1

Join Seqirus, a global leader in influenza prevention and pandemic preparedness. Powered by science and driven by purpose, our teams work together to develop innovative solutions that help protect millions of people worldwide. If you're looking to make a meaningful impact in healthcare while advancing your career, Seqirus offers the opportunity to do both.

Could you be our next Scientist I? The job is located at our Holly Springs Site. This is a full-time role onsite. You will report to the Director, Technical Development.

Job Purpose

This role will provide support for Upstream development activities projects of varying size to support cell culture and influenza candidate process improvement activities.

Major Accountabilities

Process and Product Development:

• Partner with diverse team members from various functions to contribute to the overarching TD team goals of influenza vaccine development.

• Responsible for developing and maintaining mammalian cell culture seed train (shake flasks, bioreactors, etc.) including aseptic handling of cell cultures in support of ongoing vaccine virus improvement projects.        

• Responsible for aseptically executing experiments related to virology and mammalian cell culture including virus culture sampling, sample processing, testing and analysis with standard virology/cell culture techniques and assays.

• Collaboratively design small scale experiments to characterize and define optimized growth and infection conditions for influenza vaccine process.

• Routinely design and execute small scale bioreactor (ambr15 and ambr250) experiments using DOE principals and statistical analysis for influenza vaccine process.

• May support/participate in pilot scale studies.

• Troubleshooting of instrument malfunction and identifying possible route causes for study excursions/failures.  

2.    Additional responsibilities:

• Responsible for summarizing and analyzing data and presenting study results.

• Maintain proper laboratory documentation including work instructions, lab notebooks, logbooks, appropriate electronic documentation, and lab reports. 

• Communicate (present, write-up in technical documents, etc.) results to colleagues, project teams, and management.

• When appropriate, follow all applicable SOPs and GMP requirements in support of lab activities.

Minimum Qualifications:

• Bachelor’s or postgraduate degree in Virology, Molecular Biology or related field.

• 3+ years of experience in R&D/Development setting.      

• Experience with handling and cultivation of mammalian cell culture

• Experience with small scale bioreactors and automated liquid handling systems.

• Knowledge of operation of cell culture laboratory equipment and instruments (bioreactors, bioanalyzers, cell counters, centrifuges, etc.)

• Knowledge of statistical techniques such as Design of Experiments (DOE) is desired.

• Ability to work with cross functional teams.

CSL Seqirus is part of CSL. As one of the largest influenza vaccine providers in the world, CSL Seqirus is a major contributor to the prevention of influenza globally and a transcontinental partner in pandemic preparedness. With state-of-the-art production facilities in the U.S., the U.K. and Australia, CSL Seqirus utilizes egg, cell and adjuvant technologies to offer a broad portfolio of differentiated influenza vaccines in more than 20 countries around the world.

To learn more about CSL, CSL Behring, CSL Seqirus and CSL Vifor visit https://www.csl.com/ and CSL Plasma at https://www.cslplasma.com/.

Our Benefits

For more information on CSL benefits visit How CSL Supports Your Well-being | CSL.

You Belong at CSL

At CSL, Inclusion and Belonging is at the core of our mission and who we are. It fuels our innovation day in and day out. By celebrating our differences and creating a culture of curiosity and empathy, we are able to better understand and connect with our patients and donors, foster strong relationships with our stakeholders, and sustain a diverse workforce that will move our company and industry into the future.

 To learn more about inclusion and belonging visit https://www.csl.com/careers/inclusion-and-belonging

Equal Opportunity Employer

CSL is an Equal Opportunity Employer. If you are an individual with a disability and need a reasonable accommodation for any part of the application process, please visit https://www.csl.com/accessibility-statement.

Watch our ‘On the Front Line’ video to learn more about CSL Seqirus