Position Objective: The Scientific Research Analyst will provide support services to satisfy the overall operational objectives of the National Institute of Environmental Health Sciences within the National Institutes of Health.
Duties and Responsibilities:
- Maintain and update computers associated with the X-ray facilities, and the individual workstations of NIEHS structural biologist 1
- Test, install, train, improve and design software related to crystallography, CryoEM, NMR andor graphical display of atomic structures 2
- Provide scientific support to structural biologist and other NIEHS scientists 3
- Work with and train users in methods and use of current software for crystal and CryoEM structure determination
- Work with staff on structure determination projects, particularly complex and difficult structure determinations
- Produce non-standard input files including but not limited to topology and parameter files for Phenix 4
- Work with staff on basic modeling of biochemical data on known atomic structures
- Write programs including but not limited to simple scripts, conversion programs, modification of software, and refinement programs
- Provide both technical recommendations on software usage and scientific advice about methods in x-ray structure determination including data processing, heavy-atom searching, phasing, model building, and refinement
- Produce publication quality, informative graphical representations of macromolecular structures, including use of available software, producing stereo pairs, and finding informative layouts for three-dimensional objects
- Work products and documents related to maintaining and updating computers associated with the X-ray facilities, and individual workstations of NIEHS staff involved in structural biology; testing, installing, training, improving and designing software related to crystallography, CryoEM, NMR and graphic display of atomic structures; providing support to staff.
- Work products and documents related to providing training and support in methods and use of software; working on structure determination projects; producing non-standard input files required for structural refinement; working on basic modeling of biochemical data on known atomic structures.
- Work products and documents related to writing programs, simple scripts, conversion
- programs, modification of software and refinement programs. Also provides written documentation for Materials and Methods of manuscripts prepared using output from assistance provided.
- Work products and documents related to providing technical recommendations about methods in X-ray structure determination, data processing, heavy-atom searching, phasing, model building and refinement; producing graphical representations. Also provides assistance to the structural biology community in refinement of CryoEM structures.
Basic Qualifications:
- PhD in Biochemistry, Chemistry, or Biophysics and six years of experience.
- Comprehensive knowledge of crystallography software programs
- Excellent skill in producing graphical representations of macromolecular structures for publication or presentations
Preferred Qualifications:
- Ability to communicate effectively, orally and in writing, with non-technical and technical staff
- Detail-oriented and possess strong organizational skills with the ability to prioritize multiple tasks and projects
*This job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required by this position.
To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
GAP Solutions provides reasonable accommodations to qualified individuals with disabilities. If you need an accommodation to apply for a job, email us at [email protected]. You will need to reference the requisition number of the position in which you are interested. Your message will be routed to the appropriate recruiter who will assist you. Please note, this email address is only to be used for those individuals who need an accommodation to apply for a job. Emails for any other reason or those that do not include a requisition number will not be returned.
Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, protected veteran status or other characteristics protected by law.
This position is contingent upon contract award.
Skills Required
- PhD in Biochemistry, Chemistry, or Biophysics
- Six years of experience
- Comprehensive knowledge of crystallography software programs
- Excellent skill producing graphical representations of macromolecular structures for publications or presentations
- Effective oral and written communication with technical and non-technical staff
- Detail-oriented with strong organizational skills and ability to prioritize multiple tasks and projects
What We Do
GAP Solutions, Inc. is a professional services and technology firm founded in 1999 and headquartered in Herndon, VA. It provides specialized workforce, health, and mission-focused solutions to the Department of Defense, intelligence community, and federal civilian agencies. The company's expertise spans emergency management, public health initiatives, national security, and information technology services, aiming to promote and protect the health and security of the nation.
