SAP Senior Manager (Manufacturing, Quality & Procurement)

What if the work you did every day could impact the lives of people you know? Or all of humanity?

At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.

Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible.

We are seeking an experienced SAP Senior Manager to lead Manufacturing, Quality, and Procurement capabilities, driving transformation and operational excellence through SAP S/4HANA and related solutions (PP, QM, MM, EAM, and EHS).

This role focuses on executing digital transformation, process standardization, and enabling scalable operations across manufacturing and supply chain execution. The ideal candidate combines strong business acumen with deep SAP expertise and proven team leadership experience.

Responsibilities will include

• Lead IT delivery for Manufacturing, Quality, Procurement, EAM, and EHS, ensuring alignment with business priorities and program objectives.
• Execute ERP                 transformation initiatives, process improvements, and standardization across Manufacturing, Quality, Procurement, EAM, and EHS domains.
• Collaborate with cross-functional stakeholders (Commercial, GPOs, Finance, Supply Chain, IT, and Operations) to deliver integrated end-to-end solutions.
• Oversee design, configuration, and optimization of SAP S/4HANA solutions (PP, QM, MM, EAM, EHS) in alignment with enterprise architecture.
• Lead and mentor a team of SAP analysts, functional leads, and solution architects (team size ~10+).
• Build high-performing teams and drive effective cross-functional execution.
• Manage master data governance for PP, QM, MM, EAM, and EHS.
• Ensure seamless integration across Manufacturing, Quality, EAM, EHS, Warehouse, and Transportation processes.
• Manage AMS vendors, ensuring service delivery, SLA adherence, and continuous service improvement.
• Monitor KPIs and drive continuous improvement initiative

Preferred Background, Skills, and Experience

• 12–15+ years of SAP experience across Manufacturing, Quality, Procurement, EAM, and EHS, with 4–6 years in a leadership role.
• Strong hands-on experience in SAP S/4HANA implementations or transformation programs (PP, QM, MM, EAM, EHS).
• Experience in global delivery models supporting manufacturing and supply chain operations.
• Exposure to supplier management and compliance frameworks (e.g., SOX).
• Ability to translate business requirements into scalable SAP solutions within defined architecture.
• Proven leadership, stakeholder management, and team development capabilities.
• Strong analytical, problem-solving, and communication skills.

We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information. Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws. Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process, please contact [email protected]. To learn more, visit: https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf. The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants. This role is not eligible for visa sponsorship.