Research Scientist II Mammalian Protein Expression

Job Description Summary

Biomedical Research (BR) is the global pharmaceutical research organization of Novartis. With approximately 5,400 scientists and physicians around the world, our research is focused on discovering innovative new drugs that will change the practice of medicine. We have an open and entrepreneurial culture, encouraging collaboration to make effective therapies.
The Biologics Research Center (BRC) is an integral part of Novartis Biomedical Research. Our mission at BRC is to create new modalities that tackle complex biology and enable the production of quality biotherapeutics, which translate innovative ideas of Biomedical Research investigators into medicines. To reach this goal, we rely on our scientists by nurturing an inspiring environment of intellectual curiosity and open collaboration with our partners.

 

Job Description

Joining the large-scale mammalian expression team at the Biologics Research Center provides an exciting opportunity to contribute to the global BR biologics pipeline. We offer a stimulating work environment, ample opportunities for growth and development, and the chance to make a significant impact on the future of medicine.

If you are a motivated and talented scientist with a passion for biomedical research, we invite you to apply and become a part of our dynamic team at Novartis.

Your job responsibilities will include, but are not limited to:

• Expanding and maintaining mammalian cells in suspension from small to large scale (up to 100L).
• Using stably transfected CHO cells for the expression of recombinant antibodies, antibody fragments and proteins with single-use systems.
• Generating hypotheses, designing and executing follow-up experiments, and troubleshooting issues with input from senior lab members or the manager.
• Conducting literature searches to develop and implement novel technology solutions.
• Actively participating in lab organization, including maintaining equipment and preparing sterile devices for production.
• Documenting results in detail, presenting research updates, and participating constructively in project teams and at lab meetings.

What you will bring to the role:

• At least 1 year of relevant work experience in industry with MSc University degree in a relevant life science discipline, or at least 3 years of relevant work experience in industry with either a completed Apprenticeship or BSc University degree in a relevant life science discipline
• Good theoretical and strong practical laboratory experience in mammalian cell technology (stable cell lines, Wave culture systems), cell biology and sterile technique
• High learning ability to acquire expertise in new technologies and technical equipment
• Proven experience in successfully prioritizing and keeping timelines
• Excellent organizational skills with the ability to run multiple projects in parallel
• Independent and accurate working style, results-driven and committed to quality
• Open and proactive communication, strong customer focus, ability to interact with various stakeholders
• Reliable and flexible team player, accustomed to sharing tasks and projects
• Fluency in English (oral/written); German advantageous

Desirable skills:

• Solid experience in one of the neighboring disciplines (Molecular Biology, Protein Purification)

 

Skills Desired