Research Engineer II, Fluidic Systems, Research & Early Development

Posted Yesterday
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Santa Clara, CA, USA
In-Office
69K-129K Annually
Mid level
Healthtech • Biotech • Pharmaceutical
The Role
Develop chemical formulations, assays, and processes for next-generation DNA sequencing instruments and prototypes. Operate and characterize custom systems, analytical instruments, chemicals, mixtures, and surfaces. Plan experiments, collect and analyze data, document findings, prepare reports, and communicate results. Collaborate with scientists and engineers to optimize system performance and advance sequencing technology.
Summary Generated by Built In

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections,  where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

Roche is working to make next-generation sequencing simple and accessible enough for routine use. By accelerating clinical research, streamlining workflows, and expanding assay menus, we are broadening access to genomic data and lowering barriers to adoption. From robust sample isolation and preparation tools to novel sequencing technology and advanced bioinformatics, we are developing differentiated, highly integrated end-to-end solutions for next-generation sequencing, resulting in a sample in, result out workflow.

Our Systems Technology Group, a part of Roche Sequencing Solutions, is focused on creating and advancing technologies to significantly enhance DNA sequencing workflows. We are seeking an enthusiastic, team-oriented Research Engineer II to join the effort. As a Research Engineer II, you will tackle a variety of tasks and projects that will help us advance our technology and hardware related to our next-generation DNA sequencing systems.

Your efforts will cover many aspects related to the chemical engineering and process development for instrument prototypes.

Your Role and Responsibilities:

  • Developing orthogonal assays to measure system performance.

  • Operating various and developing processes for various instruments including custom systems such as breadboards and prototypes.

  • Testing, characterizing and optimizing chemical formulations for use in DNA sequencing workflows.

  • Collecting data, documenting observations and helping to analyze, interpret and present results

  • Utilizing various types of analytical instrumentation to characterize chemicals, chemical mixtures, and surfaces related to prototype instruments. 

  • Generating experimental plans, generating reports and communicating results to a broader audience.

  • Collaborating with other scientists and engineers

A cover letter is required for this application. Please outline your relevant experience and explain why you are interested in this role and our company.

Who You Are:
(Required)

  • You have a degree in Chemical Engineering, Chemistry, Biochemistry, Molecular Biology, Biomedical Engineering, Bioengineering, or a closely related discipline

  • You have relevant research and early development experience in the life science industry: 1-5 years for a Bachelor's, 0-4 years for a Master's

Core Technical Experience: 
 

  • You have experience with molecular biology workflows, including experience working with DNA and proteins.

  • You have experience developing assays for fluorescence microscopy and Qubit or other fluorescence spectrometers.

  • You have experience with common molecular biology tools and process, such as PCR and gel electrophoresis.

  • You have a solid understanding of chemistry and physics fundamentals, including chemistry and laboratory best practices. 

  • You have a meticulous mindset.

  • You have a positive, friendly, proactive attitude and a passion for science and technology.

  • You have a desire to learn and be challenged.
     

Preferred Qualifications:
 

  • You have an advanced degree

  • You have at least 1+ years of industry experience.

  • You have experience with DNA sequencing workflows.

  • You have experience with surface chemistry.

  • You have strong interpersonal and communication skills, with the ability to explain technical concepts to non-experts and thrive in ambiguous environments.

  • You have excellent organizational skills and the ability to prioritize and manage multiple projects efficiently.

  • You exhibit a high degree of ingenuity, resourcefulness, and scientific curiosity applied to solving integration challenges and optimizing system performance in an R&D environment.

  • You have demonstrated a strong desire to learn, be challenged, and proactively challenge the status quo.

This position is based onsite in Santa Clara, CA. This is not a hybrid position.

Relocation benefits are not available for this job position. 

The expected salary range for this position based on the primary location Santa Clara, CA is $69,400 - $129,000.  Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law.  A discretionary annual bonus may be available based on individual and Company performance. 

This position also qualifies for the benefits detailed at the link provided below. 

Benefits


 

 

Who we are

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.


Let’s build a healthier future, together.

Roche is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

Skills Required

  • Bachelor's degree in Chemical Engineering, Chemistry, Biochemistry, Molecular Biology, Biomedical Engineering, Bioengineering, or a closely related discipline
  • Relevant research and early development experience in the life sciences industry: 1-5 years with a bachelor's degree or 0-4 years with a master's degree
  • Experience with molecular biology workflows, including DNA and proteins
  • Experience developing assays for fluorescence microscopy and Qubit or other fluorescence spectrometers
  • Experience with PCR and gel electrophoresis
  • Understanding of chemistry and physics fundamentals and laboratory best practices
  • Meticulous mindset
  • Positive, friendly, proactive attitude and passion for science and technology
  • Desire to learn and be challenged
  • Advanced degree
  • At least one year of industry experience
  • Experience with DNA sequencing workflows
  • Experience with surface chemistry
  • Strong interpersonal and communication skills
  • Ability to explain technical concepts to non-experts and work effectively in ambiguous environments
  • Excellent organizational skills and ability to manage multiple projects
  • Ingenuity, resourcefulness, and scientific curiosity in solving integration challenges and optimizing system performance
  • Cover letter outlining relevant experience and interest in the role and company

Roche Compensation & Benefits Highlights

The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Roche and has not been reviewed or approved by Roche.

  • Retirement Support U.S. materials describe a 401(k) with both matching and an additional company contribution, supported by formal plan documents and true‑up features. This structure is positioned as a standout element of the total package, particularly at Genentech.
  • Leave & Time Off Breadth Time‑off provisions include substantial vacation, a year‑end shutdown, and a paid six‑week sabbatical after six years. These elements indicate a recharge‑oriented approach within the U.S. offering.
  • Healthcare Strength Company materials emphasize comprehensive medical, dental, vision, and mental‑health resources alongside well‑being programs. Benefits pages consistently highlight breadth across core health coverage elements.

Roche Insights

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The Company
Provincia de Buenos Aires
93,797 Employees
Year Founded: 1896

What We Do

Roche is a global pioneer in pharmaceuticals and diagnostics focused on advancing science to improve people’s lives. The combined strengths of pharmaceuticals and diagnostics under one roof have made Roche the leader in personalised healthcare – a strategy that aims to fit the right treatment to each patient in the best way possible. Roche is the world’s largest biotech company, with truly differentiated medicines in oncology, immunology, infectious diseases, ophthalmology and diseases of the central nervous system. Roche is also the world leader in in vitro diagnostics and tissue-based cancer diagnostics, and a frontrunner in diabetes management. Founded in 1896, Roche continues to search for better ways to prevent, diagnose and treat diseases and make a sustainable contribution to society. The company also aims to improve patient access to medical innovations by working with all relevant stakeholders. Thirty medicines developed by Roche are included in the World Health Organization Model Lists of Essential Medicines, among them life-saving antibiotics, antimalarials and cancer medicines. Roche has been recognised as the Group Leader in sustainability within the Pharmaceuticals, Biotechnology & Life Sciences Industry ten years in a row by the Dow Jones Sustainability Indices (DJSI).

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