Research Associate, Process Development

Reposted 2 Days Ago
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Boulder, CO, USA
In-Office
76K-119K Annually
Mid level
Biotech
The Role
The Research Associate leads oligonucleotide project development including synthesis and purification, ensuring compliance with SOPs and cGMP, while documenting results and supporting technology transfers.
Summary Generated by Built In
Job Description

The Research Associate, Process Development candidate will be responsible for process chemistry and development activities that delivers milligram to gram quantities of active pharmaceutical ingredients (API) for oligonucleotide therapeutics. This includes assisting in developing synthetic routes, methods, and techniques in preparing, separating, purifying, analyzing, quantifying, and resolving oligonucleotide process components and objectives.

Essential duties and responsibilities include but are not limited to:

  • Studying and implementing oligonucleotide project objectives and targets related to engineering and chemical requirements to better understand requirements. Additionally, they will be encouraged to study emerging trends in oligonucleotide analytical methods and synthesis development, review professional and technical publications, establish personal networks, and benchmark state-of-the-art practices.
  • Execute process development experiments and activities. Documents analyses by completing experiment notebooks and records; implementing process chemistry applications and analyzing results of new oligonucleotide synthesis and purification methods and processes. This includes preparing process descriptions and writing technical reports to support internal technology transfer into manufacturing and preparation of client CMC submissions.
  • Applies laboratory experience in chemistry and separations to issues of process optimization, scale-up and laboratory process transfer to mid and kilo scale GMP manufacturing while adhering to standard operating procedures (SOP's) and current good manufacturing practices to maintain compliance integrity (cGMP).
  • Executes Design of Experiments (DOE) and Proven Acceptable Range (PAR) experiments to support design space understanding and process validation as they relate to oligonucleotide synthesis, process chromatography, and other purification and isolation techniques.  
Qualifications
  • Bachelors, Masters, or University Degree in chemistry, chemical engineering, or science. Equivalent or a combination of education and 2+ years' experience in a pharmaceutical environment.
  • Ability to work both independently and in a team setting on a variety of projects and use individual discretion to meet required time-sensitive objectives for assigned projects.
  • Excellent math, documentation, communication and operational troubleshooting skills. General proficiency with tools, systems, and procedures required to accomplish the job.
  • Proven knowledge of oligonucleotide synthesis, purification, ultrafiltration, conjugation, and lyophilization is advantageous.
  • Knowledge of and skill in using computer software and hardware applications, including Microsoft products and the Internet.

Additional Details

This job has a full time weekly schedule. Applications for this job will be accepted until at least June 29, 2026 or until the job is no longer posted.

The full-time equivalent pay range for this position is $76,080.00 - $118,875.00/yr plus eligibility for bonus, stock and benefits. Our pay ranges are determined by role, level, and location. Within the range, individual pay is determined by work location and additional factors, including job-related skills, experience, and relevant education or training. During the hiring process, a recruiter can share more about the specific pay range for a preferred location. Pay and benefit information by country are available at: https://careers.agilent.com/locations

Agilent Technologies, Inc. is an Equal Employment Opportunity and merit-based employer that values individuals of all backgrounds at all levels. All individuals, regardless of personal characteristics, are encouraged to apply. All qualified applicants will receive consideration for employment without regard to sex, pregnancy, race, religion or religious creed, color, gender, gender identity, gender expression, national origin, ancestry, physical or mental disability, medical condition, genetic information, marital status, registered domestic partner status, age, sexual orientation, military or veteran status, protected veteran status, or any other basis protected by federal, state, local law, ordinance, or regulation and will not be discriminated against on these bases. Agilent Technologies, Inc., is committed to creating and maintaining an inclusive in the workplace where everyone is welcome, and strives to support candidates with disabilities. If you have a disability and need assistance with any part of the application or interview process or have questions about workplace accessibility, please email [email protected] or contact +1-262-754-5030. For more information about equal employment opportunity protections, please visit www.agilent.com/en/accessibility.Travel Required: NoShift: DayDuration: No End DateJob Function: R&D

Skills Required

  • Bachelor's or Master's Degree in chemistry, chemical engineering, science or equivalent
  • 4+ years relevant experience in a pharmaceutical environment
  • Previous knowledge of oligonucleotide synthesis and purification
  • Excellent math, documentation, and communication skills

Agilent Technologies Compensation & Benefits Highlights

The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Agilent Technologies and has not been reviewed or approved by Agilent Technologies.

  • Retirement Support The core U.S. package highlights a generous 401(k) match as a strength. Retirement programs are positioned as competitive within the company’s total rewards.
  • Equity Value & Accessibility An Employee Stock Purchase Plan at a discount provides accessible equity and augments total compensation. Ownership opportunities are presented as a notable advantage alongside retirement benefits.
  • Leave & Time Off Breadth Flexible Time Off, company holidays, a personal holiday, and paid volunteer time create a broad leave offering. Time off can accrue into multiple weeks in the first year, supporting flexibility.

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The Company
HQ: Santa Clara, CA
17,369 Employees
Year Founded: 1999

What We Do

Analytical scientists and clinical researchers worldwide rely on Agilent to help fulfill their most complex laboratory demands. Our instruments, software, services and consumables address the full range of scientific and laboratory management needs—so our customers can do what they do best: improve the world around us. Whether a laboratory is engaged in environmental testing, academic research, medical diagnostics, pharmaceuticals, petrochemicals or food testing, Agilent provides laboratory solutions to meet their full spectrum of needs. We work closely with customers to help address global trends that impact human health and the environment, and to anticipate future scientific needs. Our solutions improve the efficiency of the entire laboratory, from sample prep to data interpretation and management. Customers trust Agilent for solutions that enable insights...for a better world.

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