POSITION SUMMARY
We are seeking a highly motivated individual to join the Analytical Development team as a Research Associate II / Senior Research Associate. This position is an excellent opportunity to help develop new gene editing and xenotransplantation products in an exciting and dynamic environment focused on cutting-edge molecular and cellular engineering technology.
In this role, you will be part of a small team responsible for developing and qualifying methods to assess transgene expression and function in genetically modified porcine cells. This role will involve significant cell culture work, including the isolation, growth and maintenance of primary cells, such as endothelial cells from various porcine organs, and characterizing these cells using techniques such as flow cytometry, ELISA, and PCR. To be successful in this role, you will leverage previous experience with immunological and genomic assays. This role is a full-time lab-based position in which being proactive, determined, responsible, coachable, and collaborative will help you thrive.
PRIMARY RESPONSIBILITIES
- Independently plan development, optimization, troubleshooting, and execution of robust and reproducible analytical assays to characterize genetically edited porcine animals
- Utilize various techniques to test the primary cells and/or factors they produce through routine analytical testing (including flow cytometry, ELISA, conventional and real-time PCR, etc)
- Proactively monitor, track, and bridge critical reagent inventory (e.g., cell lines, assay standards, antibodies) to maintain continuous laboratory workflow without supply gaps or delays
- Independently identify assay anomalies or failures, conduct root-cause analyses, and propose paths forward to drive group goals to timely completion
- Optimize laboratory time and material resources through disciplined sample batching and full-plate assay executions
- Partner closely with QC to lead and support internal technology transfers of analytical methods, ensuring seamless assay transitions, robustness and cross-functional alignment
- Communicate and present scientific findings at group and company meetings
- Consistently document experimental procedures and data in ELNs within standard departmental turnaround timelines
- Contribute to multiple research projects as they arise in our fast-paced, start-up environment
- Build our laboratory efforts by maintaining and adding to a productive and fun environment
QUALIFICATIONS
- B.Sc with at least 4 years of industry experience in cell biology, immunology, biomedical engineering or related discipline
- Prior experience in development, troubleshooting and routine execution of assays to characterize and measure transgene expression and potency, using a variety of methodologies, particularly flow cytometry and ELISA
- Proficiency in growing and maintaining mammalian primary cells/cell lines in culture and aseptic cell culture techniques
- Expertise in general cellular and molecular biology techniques, including ELISA, flow cytometry (FACS), and potency assays
- Demonstrated ability to self-manage daily schedules, independently prioritize tasks across multiple concurrent projects, and adapt efficiently in a fast-paced environment
- Proven track record of optimizing lab efficiency, including sample batching, material resource management, and proactive inventory tracking systems.
- Strong interpersonal skills and ability to work in teams
Skills Required
- B.Sc with at least 4 years of industry experience in cell biology, immunology, biomedical engineering or related discipline.
- Experience developing, troubleshooting, and routinely executing assays to characterize and measure transgene expression and potency, particularly using flow cytometry and ELISA.
- Proficiency in growing and maintaining mammalian primary cells/cell lines and aseptic cell culture techniques.
- Expertise in cellular and molecular biology techniques including ELISA, flow cytometry (FACS), conventional and real-time PCR, and potency assays.
- Demonstrated ability to self-manage daily schedules, prioritize across multiple concurrent projects, and adapt in a fast-paced environment.
- Proven track record of optimizing lab efficiency, including sample batching, material resource management, and proactive inventory tracking.
- Experience documenting experimental procedures and data in electronic lab notebooks (ELNs) within departmental timelines.
- Strong interpersonal skills and ability to work collaboratively in teams.
What We Do
eGenesis is revolutionizing the field of transplantation with an unparalleled, multiplexed gene editing platform for the development of human-compatible organs, tissues and cells. Harnessing the latest gene-editing techniques, eGenesis has the capability to solve the global organ crisis by providing an alternative to allotransplantation. eGenesis is uniquely positioned to reinvigorate the field of xenotransplantation by addressing both the key virology and immunology hurdles that have impeded its advancement to date and provide commercially-viable products to save and enhance the lives of patients in need.
