Role Summary
This Research Associate (RA) will support the Analytical Development team of scientists to perform routine testing of samples and prepare for analytical assays designed for AAV-based gene therapy programs. This will include assisting with maintenance of cell cultures, performing proceduralized molecular assays (e.g., qPCR/ddPCR), and maintaining the laboratory space. This RA will also assist in supporting the daily operation and organization of the research laboratory. This role requires strong communication skills, the ability to multitask, and a willingness to adapt in a fast-paced environment.
Primary Responsibilities
- Understands and interprets research protocols and procedures
- Communicates questions, observations, and/or data findings with scientists to resolve challenges and gain scientific understanding
- Independently performs routine testing methodologies for AAV gene therapy vectors – including assays PCR-based assays and/or ELISA
- Identifies risks in assay performance, communicates them effectively, and supports mitigation efforts
- Maintains cell cultures and ensures reagents/supplies are ready-to-use
- Collaborates across teams to raise awareness and/or to collect, analyze, document and report data
- Performs routine laboratory activities such as material procurement, media and reagent preparation, and inventory organization
- Participates in regular team meetings (both in-person and virtually)
Required Skills and Qualifications
- BS in Chemistry, Biochemistry, Life Sciences, Pharmaceutical Sciences, Chemical Engineering, or a related field with 1 – 3 years of relevant, hands-on experience in academia and/or industry
- Hands-on experience with gene therapy products is highly desirable
- Working knowledge of analytical assay development, including molecular, immuno-, and cell-based assays (e.g., dPCR/ddPCR/qPCR, ELISA)
- Basic understanding of FDA regulations, cGxPs, and ICH guidelines is a plus
- Proficiency in using electronic laboratory notebooks (e.g., Benchling) for documentation, data analysis, and collaboration
- Strong organizational and problem-solving skills, with the ability to manage multiple tasks in a fast-paced environment
- A proactive, team-oriented attitude and excellent communication skills.
Skills Required
- Bachelor’s degree in Chemistry, Biochemistry, Life Sciences, Pharmaceutical Sciences, Chemical Engineering, or a related field
- 1–3 years of relevant hands-on experience in academia and/or industry
- Hands-on experience with gene therapy products
- Working knowledge of analytical assay development, including molecular, immunoassay, and cell-based assays such as dPCR, ddPCR, qPCR, and ELISA
- Basic understanding of FDA regulations, cGxPs, and ICH guidelines
- Proficiency with electronic laboratory notebooks such as Benchling for documentation, data analysis, and collaboration
- Strong organizational and problem-solving skills with the ability to manage multiple tasks
- Proactive, team-oriented attitude and excellent communication skills
What We Do
LEXEO Therapeutics is a New York City-based, clinical-stage gene therapy company focused on addressing some of the most devastating genetically defined cardiovascular and central nervous system diseases affecting both larger-rare and prevalent patient populations. LEXEO’s foundational science stems from partnerships and exclusive licenses with leading academic laboratories at Weill Cornell Medical College and the University of California, San Diego, two preeminent institutions on the cutting edge of gene therapy research. LEXEO is advancing a deep and diverse pipeline of AAV-based gene therapy candidates in rare cardiovascular diseases, APOE4-associated Alzheimer’s disease, and CLN2 Batten disease, and is led by pioneers and experts with decades of collective experience in genetic medicines, rare disease drug development, manufacturing and commercialization. For more information, please visit www.lexeotx.com.
