Research Associate, Downstream Processing

Posted 8 Days Ago
Be an Early Applicant
Utrecht, NLD
In-Office
Entry level
Biotech
The Role
The Research Associate will support downstream processing by executing purification strategies, monitoring performance, and collaborating with teams on various projects in a fast-paced setting.
Summary Generated by Built In

At Genmab, we are dedicated to building extra[not]ordinary® futures, together, by developing antibody products and groundbreaking, knock-your-socks-off KYSO antibody medicines® that change lives and the future of cancer treatment and serious diseases. We strive to create, champion and maintain a global workplace where individuals’ unique contributions are valued and drive innovative solutions to meet the needs of our patients, care partners, families and employees.

Our people are compassionate, candid, and purposeful, and our business is innovative and rooted in science. We believe that being proudly authentic and determined to be our best is essential to fulfilling our purpose. Yes, our work is incredibly serious and impactful, but we have big ambitions, bring a ton of care to pursuing them, and have a lot of fun while doing so.

Does this inspire you and feel like a fit? Then we would love to have you join us!

The Role

The DSP (Downstream Processing) team is part of Drug Substance Process Development and is responsible for supporting CMC (Chemistry, Manufacturing & Controls) development through all stages of clinical progress. For pre-clinical stage programs, the team focuses on process development aiming to define suitable purification strategies for both standard and highly engineered antibody formats. In later-stage clinical programs, the team leads DSP characterization efforts to establish robust and reliable operating ranges, primarily for chromatography and TFF (Tangential Flow Filtration) steps. In addition, the team is continuously exploring opportunities to improve existing processes and introduce innovative technologies in process development and characterization. This role has been created to provide flexible, hands-on support to the DSP team. You will contribute to a variety of ad hoc projects and support colleagues during periods of increased workload, offering broad exposure across different activities within DSP. Does this sound like an opportunity for you? We invite you to submit your CV and a letter of motivation so we can get to know you better!

This is a temporary 6-month entry level position to cover a colleague’s leave. While extension is not expected, it remains dependent on business needs.

Please note that, due to the temporary nature of this position, relocation support is not available. We therefore ask that applicants are already based in, or able to commute to, the Utrecht area in the Netherlands.

Responsibilities

  • Perform and document process screening and development for both standard and heavily engineered antibody products.  

  • Execute downstream processing steps, including chromatography and TFF.  

  • Monitor and document process performance, including basic biochemical analyses of antibody products (e.g., HP-SEC).  

  • Contribute to efficient technology transfer activities to CMOs.  

  • Collaborate closely with scientists and research associates across multiple project teams.  

  • Present results in a clear and structured manner and support report writing and presentations.  

  • Contribute to ongoing laboratory management and operational tasks in close collaboration with research associates and support functions. 

Requirements

You are a strong communicator who thrives in a fast-paced, international environment with shifting priorities and varying workloads. You are an adaptable team player, able to navigate different perspectives, build alignment, and contribute to clear decision-making. You bring a positive, proactive mindset and are motivated to apply your knowledge of protein purification and characterization techniques to strengthen the DSP team. You work with precision and accuracy in both experimental execution and documentation, and you take a solution-oriented approach when results do not meet expectations.

In addition, the following qualifications are preferred:

  • A completed HLO/BSc degree or equivalent level of experience.  

  • At least 1 year of experience in a relevant industry, with familiarity in working under quality standards.  

  • Experience with downstream processing, preferably for antibody products.  

  • Hands-on experience with preparative protein chromatography techniques (e.g., affinity, ion exchange) and TFF processes. Experience with analytical methods such as HPLC or ELISA is a plus.  

  • Familiarity with relevant software such as UNICORN.  

  • A strong focus on delivering high-quality results within a quality system environment.  

  • Ability to work under tight deadlines, manage multiple tasks in parallel, and adjust priorities as needed.  

  • Strong teamwork skills and the ability to collaborate effectively with internal and external stakeholders.  

  • Good communication skills in English, as it's Genmab's primary language

About You

  • You are genuinely passionate about our purpose

  • You bring precision and excellence to all that you do

  • You believe in our rooted-in-science approach to problem-solving

  • You are a generous collaborator who can work in teams with a broad spectrum of backgrounds

  • You take pride in enabling the best work of others on the team

  • You can grapple with the unknown and be innovative

  • You have experience working in a fast-growing, dynamic company (or a strong desire to)

  • You work hard and are not afraid to have a little fun while you do so!

Locations

Genmab maximizes the efficiency of an agile working environment, when possible, for the betterment of employee work-life balance. Our offices are crafted as open, community-based spaces that work to connect employees while being immersed in our powerful laboratories. Whether you’re in one of our office spaces or working remotely, we thrive on connecting with each other to innovate.

About Genmab

Genmab is an international biotechnology company with a core purpose to improve the lives of patients through innovative and differentiated antibody therapeutics. For 25 years, its hard-working, innovative and collaborative team has invented next-generation antibody technology platforms and harnessed translational, quantitative and data sciences, resulting in a proprietary pipeline including bispecific T-cell engagers, antibody-drug conjugates, next-generation immune checkpoint modulators and effector function-enhanced antibodies. By 2030, Genmab’s vision is to transform the lives of people with cancer and other serious diseases with Knock-Your-Socks-Off (KYSO®) antibody medicines.

Established in 1999, Genmab is headquartered in Copenhagen, Denmark with international presence across North America, Europe and Asia Pacific. For more information, please visit Genmab.com and follow us on LinkedIn and X.

Genmab is committed to protecting your personal data and privacy. Please see our privacy policy for handling your data in connection with your application on our website Job Applicant Privacy Notice (genmab.com).

Please note that if you are applying for a position in the Netherlands, Genmab’s policy for all permanently budgeted hires in NL is initially to offer a fixed-term employment contract for a year, if the employee performs well and if the business conditions do not change, renewal for an indefinite term may be considered after the contract.

Skills Required

  • A completed HLO/BSc degree or equivalent experience
  • At least 1 year of experience in a relevant industry
  • Experience with downstream processing for antibody products
  • Hands-on experience with preparative protein chromatography techniques
  • Familiarity with software such as UNICORN
  • Good communication skills in English
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The Company
HQ: Plainsboro, NJ
2,179 Employees
Year Founded: 1999

What We Do

We are an international biotech company committed to improving the lives of patients through innovative and differentiated antibody therapeutics. For more than 20 years, our passionate, innovative, and collaborative team has invented next-generation antibody technology platforms and leveraged translational research and data sciences, which has resulted in a proprietary pipeline including bispecific T-cell engagers, next-generation immune checkpoint modulators, effector function enhanced antibodies and antibody-drug conjugates. To help develop and deliver novel antibody therapies to patients, we have formed 20+ strategic partnerships with biotechnology and pharmaceutical companies. By 2030, our vision is to transform the lives of people with cancer and other serious diseases with Knock-Your-Socks-Off (KYSO) antibody medicines. We are united by our core values: a passion for innovation, determination, integrity, and working as one team and respecting each other. When you work at Genmab you'll be part of a warm, fun, dynamic community seeking out and embracing the opportunity to build new and bold futures within a rapidly growing biotech company. Genmab is a place where you can be authentically you; you are empowered to innovate, build solutions, and execute; feel cared for and supported. In its totality, this makes working at Genmab an extra[not]ordinary experience. Established in 1999, we are headquartered in Copenhagen, Denmark with locations in Utrecht, the Netherlands, Princeton, New Jersey, U.S., and Tokyo, Japan. For more information, please visit Genmab.com Disclaimer: http://bit.ly/GENDisclaimer

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