Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell, T-cell receptor (TCR-T), and natural killer (NK) cell-based immunotherapy. From our three R&D sites around the world, we apply these innovative technologies to pursue the discovery of safe, efficacious and cutting-edge therapeutics for patients worldwide.
Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson & Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel). Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma.
Legend Biotech is seeking a R&D Intern as part of the Research & Early Development team based in Philadelphia, PA.
Role Overview
The R&D Intern will support research activities focused on cellular therapy and CAR-T technology. This role involves analyzing cytotoxic potential of CAR-T cells and other immune cells, performing cytokine analysis, and correlating donor variability. The intern will also assist in evaluating T cells generated with in-vivo CAR platforms and contribute to data analysis and reporting.
Key Responsibilities
- Perform cytotoxicity assays and cytokine analysis using MSD assay.
- Analyze CAR-T cells, macrophages, and other immune cells for cytotoxic potential.
- Correlate cytotoxicity data across multiple donors.
- Support in-vivo CAR platform evaluations.
- Analyze experimental data and prepare reports for manager and team.
- Maintain accurate laboratory records and follow SOPs.
- College student (BS, MS, or PhD) in Life Science, Biomedical Science, Biotechnology, Cell Science, Biology, Virology, Molecular Biology, or STEM.
- Desired Academic Grade Level: Junior/Senior/ Graduate Student.
- Interest in cellular therapy and immunotherapy.
- Knowledge of CAR-T, virus design, or immune cell assays preferred.
- Ability to commit to lab bench work (70%) and desk work (30%).
- Strong communication and organization skills.
Skills You’ll Gain
- Hands-on experience in CAR-T cell culture and transduction.
- Exposure to in-vivo CAR platform development.
- Understanding of immunotherapy approaches and assay techniques.
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Benefits
Benefits include medical, dental, and vision insurance as well as a 401(k) retirement plan with a company match that vests fully on day one. We offer eight (8) weeks of paid parental leave after just three (3) months of employment, and a paid time off policy that includes vacation time, personal time, sick time, floating holidays, and eleven (11) company holidays. Additional benefits include flexible spending and health savings accounts, life and AD&D insurance, short- and long-term disability coverage, legal assistance, and supplemental plans such as pet, critical illness, accident, and hospital indemnity insurance. We also provide commuter benefits, family planning and care resources, well-being initiatives, and peer-to-peer recognition programs; demonstrating our ongoing commitment to building a culture where our people feel empowered, supported, and inspired to do their best work.
Please note: These benefits are offered exclusively to permanent full-time employees. Contract employees are not eligible for benefits through Legend Biotech.
EEO Statement
It is the policy of Legend Biotech to provide equal employment opportunities without regard to actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, related medical conditions and lactation), gender identity or gender expression (including transgender status), sexual orientation, marital status, military service and veteran status, disability, genetic information, or any other protected characteristic under applicable federal, state or local laws or ordinances.
Employment is at-will and may be terminated at any time with or without cause or notice by the employee or the company. Legend may adjust base salary or other discretionary compensation at any time based on individual, team, performance, or market conditions.
Top Skills
What We Do
Legend Biotech is a global, commercial-stage biotechnology company developing and manufacturing novel therapies. We explore and apply innovative technologies to deliver cutting-edge options for patients around the world.
Our corporate headquarters is located in Somerset, NJ, and our manufacturing footprint includes facilities in the United States, China and the Belgium.
