Process Technology & Innovation Lead DS Upstream

Posted Yesterday
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4 Locations
Remote or Hybrid
177K-278K Annually
Expert/Leader
Healthtech • Software • Analytics • Biotech • Pharmaceutical • Manufacturing
Takeda exists to create better health for people, brighter future for the world.
The Role
Leads Takeda’s global Drug Substance Upstream process technology and innovation strategy. Owns technology roadmaps, innovation portfolios, manufacturing architecture, technology evaluation, industrialization, GMP deployment, and network-wide transformation. Partners with MSAT, Pharmaceutical Sciences, Manufacturing, Quality, Engineering, Digital, and Supply Chain teams to improve productivity, quality, sustainability, cost efficiency, and supply reliability. Builds external partnerships, advises senior leadership, and drives cross-functional innovation across a global biopharmaceutical manufacturing network.
Summary Generated by Built In

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Job Description

About the role:

As Process Technology & Innovation Lead DS Upstream, you will define and drive the global technology and innovation strategy for Drug Substance Upstream manufacturing across Takeda's network. You will lead the development and deployment of advanced process technologies, digital solutions and innovative manufacturing capabilities to strengthen operational performance, competitiveness and long-term sustainability. Working closely with Global MSAT, Pharmaceutical Sciences and cross-functional partners, you will shape the future of manufacturing through strategic investments, technology innovation and network-wide transformation.

How you will contribute:

  • Define and lead the global process technology and innovation strategy for DS Upstream, establishing a multi-year roadmap aligned with Takeda's manufacturing priorities, product pipeline and future network needs.
  • Own and govern the technology and innovation portfolio, prioritizing investments across process technologies, analytical capabilities, automation, digital solutions and AI-enabled manufacturing.
  • Drive the identification, evaluation and industrialization of innovative technologies, from initial scouting and proof-of-concept through pilot implementation, technology transfer and GMP deployment.
  • Establish and maintain the global technology blueprint and future-state manufacturing architecture, defining standards, best practices and scalable capabilities across the manufacturing network.
  • Deliver measurable business value through technology deployment, improving manufacturing robustness, productivity, cost efficiency, sustainability, quality and supply reliability.
  • Partner with Pharmaceutical Sciences, Manufacturing, Quality, Engineering, Digital and Supply Chain teams to ensure manufacturing readiness, successful technology adoption and alignment with regulatory requirements.
  • Lead innovation governance, including portfolio prioritization, investment recommendations, business case development, performance monitoring and value realization.
  • Build strategic partnerships with academia, technology providers, suppliers and industry organizations to accelerate innovation, access emerging capabilities and strengthen Takeda's competitive position.
  • Act as a strategic advisor to Global MSAT and senior leadership, fostering a culture of innovation, continuous improvement, knowledge sharing and cross-site collaboration.

What you bring to Takeda:

  • Advanced degree (Master's or PhD) in Chemical Engineering, Biotechnology, Pharmaceutical Sciences, Process Engineering or a related scientific or technical discipline, or equivalent experience.
  • Typically 15+ years of experience in pharmaceutical or biopharmaceutical manufacturing, MSAT, technical operations, process development, engineering or technology leadership.
  • Proven expertise in manufacturing process technologies, ideally within biologics Drug Substance Upstream operations, including technology transfer, process optimization and industrialization.
  • Demonstrated success in developing and executing global technology strategies, innovation portfolios and large-scale transformation initiatives within regulated GMP environments.
  • Strong understanding of emerging manufacturing technologies, automation, digital solutions, data analytics and AI applications, with experience translating innovation into measurable operational benefits.
  • Solid business acumen, including experience developing investment proposals, evaluating technical and financial feasibility, managing priorities and demonstrating value realization.
  • Excellent strategic thinking, problem-solving and stakeholder management skills, with the ability to influence senior leaders and communicate complex technical concepts effectively.
  • Proven ability to lead cross-functional teams, develop talent and drive collaboration across global, matrixed organizations and diverse cultural environments.
  • Strong external network and industry awareness, with experience building strategic partnerships and contributing to technical forums or professional organizations. Fluency in English is required.

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. 

For Location:

Lexington, MA

U.S. Base Salary Range:

$177,000.00 - $278,080.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. 


For information about our benefits, please click here.


EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

LocationsLexington, MACambridge, MA, CHE - Glattpark (Opfikon) - Zurich HQ, JPN - Yamaguchi - Hikari Plant

Worker TypeEmployee

Worker Sub-TypeRegular

Time TypeFull time

Job Exempt

Yes

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Skills Required

  • Master’s degree or PhD in Chemical Engineering, Biotechnology, Pharmaceutical Sciences, Process Engineering, or a related scientific or technical discipline, or equivalent experience
  • Typically 15 or more years of experience in pharmaceutical or biopharmaceutical manufacturing, MSAT, technical operations, process development, engineering, or technology leadership
  • Expertise in manufacturing process technologies, including technology transfer, process optimization, and industrialization
  • Experience with biologics Drug Substance Upstream operations
  • Success developing and executing global technology strategies, innovation portfolios, and large-scale transformation initiatives in regulated GMP environments
  • Understanding of emerging manufacturing technologies, automation, digital solutions, data analytics, and AI applications
  • Experience translating innovation into measurable operational benefits
  • Business acumen, including investment proposals, technical and financial feasibility evaluation, prioritization, and value realization
  • Strong strategic thinking, problem-solving, stakeholder management, and communication skills
  • Ability to lead cross-functional teams, develop talent, and drive collaboration in global matrixed organizations
  • Strong external network and industry awareness, including strategic partnerships or participation in technical forums and professional organizations
  • Fluency in English

Takeda Compensation & Benefits Highlights

The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Takeda and has not been reviewed or approved by Takeda.

  • Retirement Support — Employer-funded retirement is described as notably strong, combining a dollar-for-dollar 401(k) match with an additional company contribution that scales with age and service. Access to an employee stock purchase plan further supports long-term wealth building.
  • Parental & Family Support — Paid bonding leave for all parents, substantial adoption/surrogacy reimbursement, and robust caregiver resources (backup care and Maven family-forming support) are emphasized as core strengths. These offerings create a comprehensive safety net for a range of family situations.
  • Healthcare Strength — Multiple medical plan options (nationwide PPO/HSA and regional HMOs), employer HSA funding, and integrated mental-health and well-being programs signal depth in coverage. Preventive care is covered in-network, and plan choices by state expand access.

Takeda Insights

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The Company
HQ: Cambridge, MA
50,000 Employees
Year Founded: 1781

What We Do

For over 240 years, Takeda’s propensity to evolve has driven the next generation of innovation, and as a future-focused organization, we’re continuing to drive forward with endurance in our steadfast pursuit to achieve the best outcomes for our patients in a rapidly changing world.  We have been preparing for this period of value creation by investing in data, digital and technology, and we’re proud of our employees and their commitment to turning groundbreaking ideas into life-changing impacts.   Since our founding in Japan, integrity and putting patients first have been at the heart of our identity, and we will emerge ready for our future as one of the most trusted and science-driven digital biopharmaceutical companies. Join a team where your innovation impacts lives.   Together, we’ll realize improved outcomes by improving data quality, enhancing launch execution and improving the patient journey. You’ll play a critical role in accelerating data collection and increasing accuracy across all parts of the business. Patients across the globe will benefit from access to treatments afforded by greater opportunities and efficiency in our research and development.  

Why Work With Us

We connect to our history and Japanese heritage through everything we do to bring our purpose, values, vision, and imperatives to life. We are committed to bringing better health and a brighter future to patients. Being a part of Takeda means having the opportunity to be a part of something bigger than yourself.

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