Process Technology & Innovation Lead DS Downstream

Posted Yesterday
Be an Early Applicant
6 Locations
Remote or Hybrid
177K-278K Annually
Expert/Leader
Healthtech • Software • Analytics • Biotech • Pharmaceutical • Manufacturing
Takeda exists to create better health for people, brighter future for the world.
The Role
Leads Takeda’s global Drug Substance Downstream process technology and innovation strategy. Oversees innovation portfolios spanning process technologies, automation, analytics, digital solutions, and AI; drives technology scouting, industrialization, scaling, GMP deployment, and lifecycle management. Establishes manufacturing technology blueprints, governs investment and deployment decisions, and delivers improvements in productivity, quality, sustainability, cost, and supply reliability. Builds cross-functional global partnerships, advises senior leadership, develops technical talent, and promotes innovation across the manufacturing network.
Summary Generated by Built In

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Job Description

About the role:

As the Process Technology & Innovation Lead – DS Downstream, you will define and drive the global technology and innovation strategy for Drug Substance Downstream manufacturing across Takeda's network. You will lead the development and deployment of advanced process technologies, automation, digital solutions and AI-enabled capabilities to strengthen manufacturing competitiveness, efficiency and resilience. Working closely with Pharmaceutical Sciences and global manufacturing teams, you will shape future manufacturing capabilities and deliver sustainable business value through innovation.

How you will contribute:

  • Define and execute the global process technology and innovation strategy for Drug Substance Downstream manufacturing, translating strategic priorities into a multi-year roadmap aligned with enterprise objectives, product pipeline requirements and future manufacturing needs.
  • Lead the innovation portfolio across process technologies, analytical capabilities, automation, digital solutions and AI applications, establishing priorities, investment recommendations, resource requirements and value realization plans.
  • Oversee the identification, evaluation, industrialization and scaling of transformative technologies, from technology scouting and proof-of-concept through pilot implementation, technology transfer, GMP deployment and lifecycle management.
  • Establish and govern the Downstream technology blueprint and future manufacturing architecture, defining process platforms, technical standards, digital capabilities and scalable deployment strategies across the global manufacturing network.
  • Drive measurable improvements in manufacturing robustness, productivity, cost efficiency, sustainability, quality performance and supply reliability through disciplined innovation deployment and performance monitoring.
  • Chair the Process Technology and Innovation Governance Board for the assigned modality, overseeing roadmap approvals, portfolio prioritization, technology investments, harmonization initiatives and deployment decisions.
  • Build and lead cross-functional innovation networks involving Manufacturing, Quality, Engineering, Digital, Supply Chain, Procurement and Pharmaceutical Sciences, while developing strategic partnerships with academia, suppliers, technology providers and industry organizations.
  • Serve as a strategic advisor to Global MSAT and GSQ leadership on emerging technologies, manufacturing capability risks, investment priorities and long-term transformation opportunities, ensuring alignment with regulatory requirements and enterprise strategy.
  • Foster a culture of innovation, experimentation and continuous improvement, developing organizational capabilities, promoting knowledge sharing and representing Takeda in external industry forums and strategic innovation partnerships.

What you bring to Takeda:

  • Advanced degree (Master's or PhD) in Chemical Engineering, Pharmaceutical Sciences, Biotechnology, Bioprocess Engineering or a related scientific or engineering discipline, or equivalent experience.
  • Typically 15+ years of experience in pharmaceutical or biopharmaceutical manufacturing, MSAT, technical operations, process development, engineering or technology leadership, ideally including Drug Substance Downstream processing and global strategic initiatives.
  • Demonstrated success in developing and implementing technology strategies, innovation portfolios and large-scale transformation programs within regulated pharmaceutical or biopharmaceutical manufacturing environments.
  • Proven ability to evaluate, industrialize and scale innovative process technologies, automation, digital solutions and AI-enabled capabilities, delivering measurable operational and business improvements.
  • Strong strategic and commercial acumen, with experience developing investment proposals, business cases, portfolio priorities and benefits realization frameworks.
  • Extensive experience operating in complex global matrix organizations, influencing senior stakeholders and driving cross-functional collaboration across geographies and business functions.
  • Strong people leadership and talent development capabilities, with experience building high-performing teams, developing technical expertise and fostering an innovation-driven culture.
  • Excellent communication, stakeholder management and strategic problem-solving skills, with the ability to translate complex technical concepts into clear business recommendations for executive leadership.
  • Recognized expertise in manufacturing technology and innovation, supported by engagement with industry networks, technical advisory groups, scientific forums or external partnerships, combined with fluency in English.

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. 

For Location:

Lexington, MA

U.S. Base Salary Range:

$177,000.00 - $278,080.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. 


For information about our benefits, please click here.


EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

LocationsLexington, MABEL - Lessines, CHE - Glattpark (Opfikon) - Zurich HQ, JPN - Yamaguchi - Hikari Plant, USA - MA - Cambridge, Vienna, Austria

Worker TypeEmployee

Worker Sub-TypeRegular

Time TypeFull time

Job Exempt

Yes

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Skills Required

  • Master’s degree or PhD in Chemical Engineering, Pharmaceutical Sciences, Biotechnology, Bioprocess Engineering, or a related scientific or engineering discipline, or equivalent experience
  • Typically 15+ years of experience in pharmaceutical or biopharmaceutical manufacturing, MSAT, technical operations, process development, engineering, or technology leadership
  • Experience in Drug Substance Downstream processing and global strategic initiatives
  • Success developing and implementing technology strategies, innovation portfolios, and large-scale transformation programs in regulated pharmaceutical or biopharmaceutical manufacturing environments
  • Experience evaluating, industrializing, and scaling innovative process technologies, automation, digital solutions, and AI-enabled capabilities
  • Experience developing investment proposals, business cases, portfolio priorities, and benefits realization frameworks
  • Extensive experience in complex global matrix organizations with senior stakeholder influence and cross-functional collaboration
  • People leadership and talent development experience, including building high-performing teams and fostering innovation cultures
  • Excellent communication, stakeholder management, and strategic problem-solving skills
  • Ability to translate complex technical concepts into clear business recommendations for executive leadership
  • Recognized expertise in manufacturing technology and innovation, supported by industry networks, technical advisory groups, scientific forums, or external partnerships
  • Fluency in English

Takeda Compensation & Benefits Highlights

The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Takeda and has not been reviewed or approved by Takeda.

  • Retirement Support — Employer-funded retirement is described as notably strong, combining a dollar-for-dollar 401(k) match with an additional company contribution that scales with age and service. Access to an employee stock purchase plan further supports long-term wealth building.
  • Parental & Family Support — Paid bonding leave for all parents, substantial adoption/surrogacy reimbursement, and robust caregiver resources (backup care and Maven family-forming support) are emphasized as core strengths. These offerings create a comprehensive safety net for a range of family situations.
  • Healthcare Strength — Multiple medical plan options (nationwide PPO/HSA and regional HMOs), employer HSA funding, and integrated mental-health and well-being programs signal depth in coverage. Preventive care is covered in-network, and plan choices by state expand access.

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The Company
HQ: Cambridge, MA
50,000 Employees
Year Founded: 1781

What We Do

For over 240 years, Takeda’s propensity to evolve has driven the next generation of innovation, and as a future-focused organization, we’re continuing to drive forward with endurance in our steadfast pursuit to achieve the best outcomes for our patients in a rapidly changing world.  We have been preparing for this period of value creation by investing in data, digital and technology, and we’re proud of our employees and their commitment to turning groundbreaking ideas into life-changing impacts.   Since our founding in Japan, integrity and putting patients first have been at the heart of our identity, and we will emerge ready for our future as one of the most trusted and science-driven digital biopharmaceutical companies. Join a team where your innovation impacts lives.   Together, we’ll realize improved outcomes by improving data quality, enhancing launch execution and improving the patient journey. You’ll play a critical role in accelerating data collection and increasing accuracy across all parts of the business. Patients across the globe will benefit from access to treatments afforded by greater opportunities and efficiency in our research and development.  

Why Work With Us

We connect to our history and Japanese heritage through everything we do to bring our purpose, values, vision, and imperatives to life. We are committed to bringing better health and a brighter future to patients. Being a part of Takeda means having the opportunity to be a part of something bigger than yourself.

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