Principal Systems Engineer

Posted Yesterday
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Jacksonville, FL, USA
In-Office
134K-202K Annually
Senior level
Healthtech
The Role
The Principal Systems Engineer leads system development for ENT medical devices, translating clinical needs into requirements and ensuring integration across engineering disciplines. Responsibilities include system architecture, risk management, and cross-functional collaboration to deliver compliant medical systems.
Summary Generated by Built In
We anticipate the application window for this opening will close on - 28 May 2026


 

At Medtronic you can begin a life-long career of exploration and innovation, while helping champion healthcare access and equity for all. You’ll lead with purpose, breaking down barriers to innovation in a more connected, compassionate world.

A Day in the Life

         

         

Across our global Neuroscience organization, we advance care for some of medicine’s most complex neurological and spinal conditions. By combining innovative technology, data-driven insights, and deep clinical expertise, we partner with physicians and health systems to improve how patients are treated and supported throughout their care journey.

Our Ear, Nose & Throat (ENT) Operating Unit provides innovative technologies that support clinicians in treating sinus, otology, head and neck, skull base, airway, and related conditions. Our ENT technology includes powered instruments, image-guided surgical systems, and sinus implants that enhance precision, safety, and efficiency across both office and operating room settings—helping improve patient outcomes in a complex and evolving specialty.

Check us out on LinkedIn: Medtronic ENT

At Medtronic, we bring bold ideas forward with speed and decisiveness to put patients first in everything we do. We’re working onsite 4 days a week to drive performance, foster an environment of belonging, and collaborate to inspire as we engineer the extraordinary. 

The Principal Systems Engineer provides technical leadership for complex ENT system development programs. This role is responsible for defining system architecture, translating clinical and business needs into system requirements, and ensuring effective integration across hardware, software, firmware, and mechanical subsystems. The individual partners closely with cross‑functional teams including R&D, Quality, Regulatory, Clinical, and Operations to deliver safe, effective, and compliant medical device systems that support ENT surgical procedures.


Responsibilities may include the following and other duties may be assigned:

  • Lead system architecture development for ENT capital equipment and associated instruments or accessories. 

  • Translate user needs and clinical workflow requirements into system‑level functional and performance requirements. 

  • Apply critical thinking to solve systems integration problems and make recommendations 

  • Utilize architecture design tools to develop and document system-level interactions. 

  • Develop and maintain system requirements and ensure traceability through verification and validation. 

  • Coordinate cross‑disciplinary integration across hardware, embedded software, firmware, and mechanical subsystems. 

  • Lead system‑level risk management activities including hazard analysis and FMEA in accordance with ISO 14971. 

  • Drive system design trade‑offs and technical decision making across engineering teams. 

  • Provide system traceability reports as needed throughout the design development phases. 

  • Collaborate with Quality and Regulatory teams to ensure compliance with design control requirements and applicable standards. 

  • Provide technical mentorship and systems engineering guidance to engineers across development programs. 

Must Have: Minimum Requirements:

  • Bachelor’s degree in Engineering or related technical discipline. 

  • Minimum of 7 years of relevant engineering experience

  • Or advanced degree with 5 years of experience

  • Or PhD with 3 years relevant experience.

Nice to Have:

  •  Advanced degree in Systems Engineering, Biomedical Engineering, Electrical Engineering, or related field. 

  • Experience developing regulated medical devices. 

  • Experience with surgical systems, capital equipment, or ENT‑related technologies. 

  • Experience with requirements management and task tracking tools such as Polarion, Codebeamer, Jeera, or similar platforms. 

  • Familiarity with medical device standards and regulations such as FDA design controls, ISO 13485, and IEC 62304. 

  • Experience mentoring engineers or providing technical leadership across programs. 

  • Experience developing and managing system requirements for complex, multi‑disciplinary products. 

  • Experience leading system integration across hardware, software, and mechanical domains. 

  • Demonstrated ability to lead technical decision making within cross‑functional teams. 

For Baccalaureate degrees earned outside of the United States, a degree that satisfies the requirements of 8 C.F.R. § 214.2(h)(4)(iii)(A) is required.

Physical Job Requirements

The above statements are intended to describe the general nature and level of work being performed by employees assigned to this position, but they are not an exhaustive list of all the required responsibilities and skills of this position. 

The physical demands described within the Responsibilities section of this job description are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. For Office Roles: While performing the duties of this job, the employee is regularly required to be independently mobile. The employee is also required to interact with a computer, and communicate with peers and co-workers. Contact your manager or local HR to understand the Work Conditions and Physical requirements that may be specific to each role.

U.S. Work Authorization & Sponsorship

At Medtronic, we are committed to fostering an environment where employees can thrive and make a meaningful impact. In alignment with our enterprise-wide workforce planning approach, U.S. work authorization sponsorship (H-1B, TN, J, etc.) is offered exclusively for Principal-level roles and above, where specialized expertise aligns with long-term business needs. Roles below the Principal level require candidates to possess unrestricted U.S. work authorization at the time of hire and for the duration of employment.

Join us in our mission to alleviate pain, restore health, and extend life—where your unique background and perspective are valued.

Benefits & Compensation
 

Medtronic offers a competitive Salary and flexible Benefits Package
A commitment to our employees lives at the core of our values. We recognize their contributions. They share in the success they help to create.  We offer a wide range of benefits, resources, and competitive compensation plans designed to support you at every career and life stage.
 

Salary ranges for U.S (excl. PR) locations (USD):$134,400.00 - $201,600.00


This position is eligible for a short-term incentive called the Medtronic Incentive Plan (MIP).

The base salary range is applicable across the United States, excluding Puerto Rico and specific locations in California. The offered rate complies with federal and local regulations and may vary based on factors such as experience, certification/education, market conditions, and location. Compensation and benefits information pertains solely to candidates hired within the United States (local market compensation and benefits will apply for others).

The following benefits and additional compensation are available to those regular employees who work 20+ hours per week: Health, Dental and vision insurance, Health Savings Account, Healthcare Flexible Spending Account, Life insurance, Long-term disability leave, Dependent daycare spending account, Tuition assistance/reimbursement, and Simple Steps (global well-being program).

 

The following benefits and additional compensation are available to all regular employees: Incentive plans, 401(k) plan plus employer contribution and match, Short-term disability, Paid time off, Paid holidays, Employee Stock Purchase Plan, Employee Assistance Program, Non-qualified Retirement Plan Supplement (subject to IRS earning minimums), and Capital Accumulation Plan (available to Vice Presidents and above, or subject to IRS earning minimums).

 

Regular employees are those who are not temporary, such as interns.  Temporary employees are eligible for paid sick time, as required under applicable state law, and the Employee Stock Purchase Plan. Please note some of the above benefits may not apply to workers in Puerto Rico.

 

Further details are available at the link below:

Medtronic benefits and compensation plans

About Medtronic

We lead global healthcare technology and boldly attack the most challenging health problems facing humanity by searching out and finding solutions.
Our Mission — to alleviate pain, restore health, and extend life — unites a global team of 95,000+ passionate people. 
We are engineers at heart— putting ambitious ideas to work to generate real solutions for real people. From the R&D lab, to the factory floor, to the conference room, every one of us experiments, creates, builds, improves and solves. We have the talent, diverse perspectives, and guts to engineer the extraordinary.

Learn more about our business, mission, and our commitment to diversity here.

It is the policy of Medtronic to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state or local law. In addition, Medtronic will provide reasonable accommodations for qualified individuals with disabilities.

If you are applying to perform work for Medtronic, Inc. (“Medtronic”) in any position which will involve performing at least two (2) hours of work on average each week within the unincorporated areas of Los Angeles County, you can find here a list of all material job duties of the specific job position which Medtronic reasonably believes that criminal history may have a direct, adverse and negative relationship potentially resulting in the withdrawal of a conditional offer of employment. Medtronic will consider for employment qualified job applicants with arrest or conviction records in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.

Skills Required

  • Bachelor's degree in Engineering or related technical discipline.
  • 7 years of relevant engineering experience OR advanced degree with 5 years OR PhD with 3 years

Medtronic Compensation & Benefits Highlights

The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Medtronic and has not been reviewed or approved by Medtronic.

  • Parental & Family Support Paid leave for birthing and non-birthing parents is positioned as notably generous, with additional Family Care Leave available for a range of caregiving needs. Fertility, adoption, donor, and surrogacy support adds depth for different paths to family-building.
  • Retirement Support A 401(k) match and an employee stock purchase plan are presented as meaningful long-term savings tools. Scholarship and tuition programs further reinforce financial security beyond salary.
  • Healthcare Strength Medical, dental, and vision coverage is consistently described as a strong part of the total rewards package. Mental health resources, critical illness coverage, and wellness supports broaden the overall health offering.

Medtronic Insights

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The Company
HQ: Minneapolis, MN
80,303 Employees
Year Founded: 1949

What We Do

Medtronic is a global healthcare solutions company operating in approximately 160 countries. We are committed to improving lives through our medical technologies, services, and solutions. Since our beginning, 60 years ago, our Mission has remained the same: to alleviate pain, restore health, and extend life for people around the world. The Mission is our ethical framework and inspirational goal guiding our day-to-day work. It reminds us that our efforts are transforming millions of lives each year. To meet the needs of patients and healthcare professionals around the globe, we operate from more than 370 locations in approximately 160 countries.

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