Scale Biosciences, Inc. (“ScaleBio”) is an early-stage life sciences technology and tools company developing advanced single-cell solutions based upon the Company's highly parallelized way to barcode cells which allows for exponential scalability. Our mission is to democratize scalable, easy-to-adopt, extensible, cost-effective single-cell applications across a broad range of systems and sample types within the Life Sciences community.
At ScaleBio we have a shared mission built upon a demonstrated technology with long term investment commitments. We are seeking team members that have a passion for developing technologies that benefit the broader researcher community in the discovery of human biology. Such individuals should also have a strong interest in single-cell sequencing as a disruptive and enabling technology.
We are seeking an enthusiastic Principal Scientist, Technology Transfer with a passion for innovation, operations, and for the production of tools that benefit the life science community. The successful candidate will lead Continuous Process Improvement (CPI) initiatives to turn great ideas into reality to realize product, process and cost gains through cross-functional partnerships with operations, R&D, finance, field support, and quality. In this role they will evaluate process, products, and materials and implement improvements across the organization to facilitate production of high-quality single cell RNA, methylation, and multi-omics products and enable customer-centered product design and workflows.
They will be self-motivated, enthusiastic, have a proven track record of CPI, and will bring knowledge of lean six sigma operational excellence and enthusiasm to the organization to support and maintain scalable systems and process for product quality and traceability.
Job duties will include but not limited to:
- Leading the effort to transfer workflows, materials, protocols, quality testing from R&D to the manufacturing team.
- Independent design and execution of experiments to address product stability, scalability, and alternative materials for kit production and services.
- Partner with development team to set incoming material acceptance criteria, in process QC, and final product quality specifications.
- Lead projects as the technical expert or SME and report out data.
- Supporting root cause analysis and production incidents with Scale’s QMS to deliver improvements.
- Support assay development to assure best customer facing workflows and processes are developed for customer success.
- Supporting product quality and investigations for CAPAs, NCRs and implementing corrective action.
- Lead and support product lifecycle management.
- Communicate effectively with peers / management and report initiatives to corporate goals.
- Ability to cross-functionally work within and across the organization effectively as a team player.
- Lead operational excellence initiatives in MFG and R&D.
What You'll Bring to the Team:
- An advanced degree in biology, chemistry, biochemistry, or a related field with 7+ years of biotechnology/pharmaceutical experience in Tech transfer or CPI.
- Strong background in molecular biology techniques, including DNA/RNA purification and quantification, PCR/qPCR, Cell biology, enzymatic assays, and Next Generation Sequencing (NGS) techniques, RNA based sequencing assays, methylation based assays, single cell or targeted enrichment assays.
- Single cell workflows and knowledge a bonus.
- A can-do attitude and creative problem solving skills.
- Management/supervisory experience and working with cross functional teams.
- Knowledge of traditional operational excellence processes: Lean 6 sigma, Kaizen, Gemba, visualizations, 5S, KanBan, standard work models etc.
- Ability to excel in a fast-paced, ambiguous, and changing landscape.
- Strong attention to detail.
- Strong proactive ability to anticipate problems and mitigate risk.
Physical Activities:
- Working in controlled laboratory environment.
- Must be able to stand for long periods of time while performing duties.
- Must be able to work safely with chemicals and hazardous materials.
- Must be able to lift up to 20 lbs.
Below is the salary range for this full-time position. The actual base pay will depend on several factors unique to each candidate, including one’s skills, qualifications, and experience.
Base Salary Range – $155,000 - $175,000 USD
ScaleBio provides competitive compensation, health and dental benefits, 401K retirement saving plan, state of the art laboratory facilities, and an exciting and innovative culture with the opportunity to enable a novel single cell technology. To learn more please visit our website www.scale.bio. ScaleBio is an equal opportunity employer committed to hiring a diverse and inclusive workforce.
Any and all communications regarding job openings will be communicated by a [email protected] email address
Top Skills
What We Do
Single cell sequencing solutions company, leveraging patented split-pool barcoding and combinatorial indexing technology, that provides library preparation products that enable unprecedented sample indexing and cell throughput across broad range of genomic, transcriptomic, epigenomic, proteomic and multi-omics applications.
