Job Description
Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine? Join us as a Scientist/Senior Scientist, Computational Chemistry in Cambridge, MA, US or Fujisawa, Kanagawa, Japan.
At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.
OBJECTIVES/PURPOSE
- Work as part of a multi-disciplinary team of medicinal chemists, structural biologists, data scientists and biologists and provide computational expertise to advance drug discovery projects.
- Contribute to drug discovery efforts across various modalities including small molecules, PROTACs, RNA inhibitors, peptides, and more.
- Implement and execute innovative computational methodologies and tools such as AI, free energy, and cheminformatics approaches to support drug discovery efforts.
ACCOUNTABILITIES
- Demonstrate an understanding of computational chemistry principles and their application within a multidisciplinary drug discovery environment.
- Independently design, develop and execute research assignments, contributing to multiple projects.
- Identify, develop, validate, and implement innovative computational approaches that enhance research productivity and success.
- Provide key technical knowledge and input to project teams to drive decision-making in drug discovery projects.
Requirements:
- PhD degree in Chemistry or equivalent
- Ideally 2+ years of experience in industry
- Experience with a variety of computational tools and methodology including large-scale virtual screening, ligandability analyses, homology modeling, quantum mechanics, pharmacophore elucidation, machine learning and more against common drug discovery targets (GPCRs, Kinases etc.).
- Comprehensive experience in data mining and data analysis.
- Familiarity with organic and synthetic chemistry concepts
- Provide project teams with computational strategies to inform, influence, and prioritize designs for potency/selectivity and improve ADME/Tox endpoints.
- Contribute to the development and deployment of design and/or AI platforms to impact drug discovery.
- Familiarity with standard computational chemistry software including Schrodinger Suites, KNIME, and more.
- Proficiency in scientific scripting and programming languages including python.
- Business level of Japanese and English language proficiency
Apply now and be part of our mission to deliver Better Health and a Brighter Future to people around the world.
Takeda Compensation and Benefits Summary:
- Allowances: Commutation, Housing, Overtime Work etc.
- Salary Increase: Annually, Bonus Payment: Twice a year
- Working Hours: Headquarters (Osaka/ Tokyo) 9:00-17:30, Production Sites (Osaka/ Yamaguchi) 8:00-16:45, (Narita) 8:30-17:15, Research Site (Kanagawa) 9:00-17:45
- Holidays: Saturdays, Sundays, National Holidays, May Day, Year-End Holidays etc. (approx. 123 days in a year)
- Paid Leaves: Annual Paid Leave, Special Paid Leave, Sick Leave, Family Support Leave, Maternity Leave, Childcare Leave, Family Nursing Leave.
- Flexible Work Styles: Flextime, Telework
- Benefits: Social Insurance, Retirement and Corporate Pension, Employee Stock Ownership Program, etc.
Important Notice concerning working conditions:
- It is possible the job scope may change at the company's discretion.
- It is possible the department and workplace may change at the company's discretion.
Locations
Fujisawa, Japan
Worker Type
Employee
Worker Sub-Type
Regular
Time Type
Full time
Top Skills
What the Team is Saying
What We Do
For over 240 years, Takeda’s propensity to evolve has driven the next generation of innovation, and as a future-focused organization, we’re continuing to drive forward with endurance in our steadfast pursuit to achieve the best outcomes for our patients in a rapidly changing world.
We have been preparing for this period of value creation by investing in data, digital and technology, and we’re proud of our employees and their commitment to turning groundbreaking ideas into life-changing impacts.
Since our founding in Japan, integrity and putting patients first have been at the heart of our identity, and we will emerge ready for our future as one of the most trusted and science-driven digital biopharmaceutical companies. Join a team where your innovation impacts lives.
Together, we’ll realize improved outcomes by improving data quality, enhancing launch execution and improving the patient journey. You’ll play a critical role in accelerating data collection and increasing accuracy across all parts of the business. Patients across the globe will benefit from access to treatments afforded by greater opportunities and efficiency in our research and development.
Why Work With Us
We connect to our history and Japanese heritage through everything we do to bring our purpose, values, vision, and imperatives to life. We are committed to bringing better health and a brighter future to patients. Being a part of Takeda means having the opportunity to be a part of something bigger than yourself.
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Hybrid Workspace
Employees engage in a combination of remote and on-site work.
Takeda's hybrid policy varies by role. Be sure to ask your recruiter about the requirements for the role that you are applying for.
