Principal Research Scientist I – Analytical Development – PDST – Late-Stage Process Analytics
About AbbVie
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.
Job DescriptionThe Principal Scientist I will be an integral part of the Process Analytics team in the Operations – Product Development Science and Technology – Biologics division. The role involves leading analytical activities within a high-throughput testing group supporting biologics products with a focus on advancing AbbVie’s late-stage clinical programs. This position calls for an individual with a strong technical analytical background, demonstrated leadership and organizational skills and the ability to effectively communicate and work cross-functionally.
Responsibilities:
- Lead analytical activities within a high-throughput testing group supporting biologics process development for late-stage programs.
- Serve as the subject matter expert for separation-based methods, including HPLC and capillary electrophoresis.
- Evaluate and select effective fit for purpose analytical technologies and methods to meet process development needs.
- Provide expertise and support for method development, execution, and troubleshooting. Provide direct technical guidance and oversight to scientists executing sample testing with hands on lab support when needed.
- Partner with process development SMEs for interpretation and understanding of analytical data.
- Oversee sample testing schedule and prioritization; drive timely delivery of high-quality testing results.
- Support implementation of automation and high-throughput experimentation workflows.
- Drive continuous improvement initiatives to enhance lab efficiency and capability.
- Mentor, train and supervise junior scientists.
- PhD in chemistry, biology, biochemistry, chemical engineering, or related technical discipline with 6+ years of relevant professional experience working in analytical development or process analytics; MS degree with minimum of 10+ years of relevant experience.
- Proven experience leading analytical development activities for biologics development, including mAbs, multi-specifics, antibody-drug conjugates, and fusion proteins.
- Hands on method development experience in protein and impurity analysis techniques such as HPLC, capillary electrophoresis, and other relevant methods for biologics required. Experience with mass spectrometry and ELISA is a plus.
- Previous experience with automation is a plus.
- Highly organized with ability to multitask and drive efficient workflows.
- Ability to think critically and demonstrate troubleshooting and problem-solving skills.
- Strong people leadership skills and demonstrated ability to foster an engaging, inclusive and collaborative team environment. Direct people management experience required.
- Excellent communication and interpersonal skills. Ability to work effectively across functions, anticipating and addressing overall program development needs.
- An independent, self-motivated, proactive individual who thrives in a fast-paced team environment.
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
- The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
- We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
- This job is eligible to participate in our long-term incentive programs.
Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html
US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:
https://www.abbvie.com/join-us/reasonable-accommodations.html
Skills Required
- PhD in chemistry, biology, biochemistry, chemical engineering, or a related technical discipline with 6 or more years of relevant analytical development or process analytics experience
- Alternatively, an MS degree with at least 10 years of relevant experience
- Experience leading analytical development activities for biologics, including monoclonal antibodies, multispecifics, antibody-drug conjugates, or fusion proteins
- Hands-on method development experience using HPLC, capillary electrophoresis, and other protein and impurity analysis techniques
- Direct people management experience
- Strong technical analytical background and demonstrated leadership, organizational, communication, troubleshooting, and problem-solving skills
- Experience with mass spectrometry and ELISA
- Previous experience with laboratory automation
AbbVie Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about AbbVie and has not been reviewed or approved by AbbVie.
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Retirement Support — Retirement programs are portrayed as a standout, with a dollar‑for‑dollar 401(k) match up to 6% and an additional annual company contribution based on age and service. Feedback suggests this materially boosts perceived total compensation for many U.S. employees.
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Parental & Family Support — Paid parental and caregiver leave are emphasized, including up to 12 weeks of fully paid parental leave for all parents and 4 weeks of paid caregiver leave in the U.S. Feedback suggests these policies are a meaningful differentiator for employees balancing family needs.
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Leave & Time Off Breadth — Time off is described as extensive, with tiered vacation that scales with tenure, 17 company holidays, and two paid volunteer days in the U.S. Feedback suggests the breadth of leave contributes notably to overall benefits satisfaction.
AbbVie Insights
What We Do
AbbVie is a global biopharmaceutical company focused on creating medicines and solutions that put impact first — for patients, communities, and our world. We aim to address complex health issues and enhance people's lives through our core therapeutic areas: immunology, oncology, neuroscience, eye care, aesthetics and other areas of unmet need.
