Principal Research Associate, Analytical Development

Reposted 10 Days Ago
Be an Early Applicant
2 Locations
In-Office
90K-144K Annually
Mid level
Healthtech • Biotech
The Role
Coordinate characterization and comparability studies, execute testing, analyze data, draft protocols, communicate findings, and write SOPs. Requires biophysical characterization experience.
Summary Generated by Built In

The Role:
Reporting to the Head of the Product Characterization group, the individual in this role will coordinates characterization and comparability studies to support advancement of Moderna’s pipeline, including commercial products. The incumbent should be familiar and have hands-on experience with most of the routine biochemical and biophysical characterization techniques used for RNA structural characterization, including mass spectrometry, spectroscopy, calorimetry, liquid chromatography, ELISA, light scattering and next generation sequencing.  Demonstrated writing skills are required for protocol drafting and report compilation. Polished communication skills are essential considering that the incumbent will regularly interact with other RAs and Scientists within the Analytical Development, Analytical Technical Operations and Process Development teams. The individual will present scientific findings/results internally or externally. The individual will also evaluate new technologies, optimize methods and write methods SOPs.

Here’s What You’ll Do:

  • Draft testing protocols and compile characterization reports in support of regulatory filings

  • Coordinate sample generation and sample submissions for partner groups

  • Execute testing for various characterization assays including calorimetry, spectroscopy, light scattering and next generation sequencing

  • Perform data analysis and data trending utilizing good documentation practices

  • Record and communicate findings, present results at internal or cross-functional meetings

  • Write/Revise SOPs related to job function

  • Collaborate with other members within the with R&D departments throughout the company

  • Perform general laboratory support activities including equipment maintenance and housekeeping

  • Be accountable for project success and results delivery

Here’s What You’ll Bring to the Table:

  • BS with at least 4 years of industry experience, or MS with at least 2 years of industry experience (Biophysics, Chromatography, Biochemistry, Molecular Biology, or related science),

  • Experience in performing biophysical characterization with focus on mRNA structural characterization

  • Experience with spectroscopy and calorimetry

  • Excellent writing and documentation skills

  • Excellent interpersonal and collaborative skills

  • Ability to work independently and effectively in a highly dynamic environment

  • This position is site-based, requiring you to be at Moderna’s site full-time. This position is not eligible for remote work.

  • At Moderna, we are focused on delivering on our mission by enabling talent to thrive. For this role, we are currently unable to offer immigration sponsorship. Candidates must already hold work authorization in US and be able to maintain that status without the need for future sponsorship.

Pay & Benefits

At Moderna, we believe that when you feel your best, you can do your best work.  That’s why our US benefits and global well-being resources are designed to support you—at work, at home, and everywhere in between.

  • Best-in-class healthcare coverage, plus voluntary benefit programs to support your unique needs

  • A holistic approach to well-being, with access to fitness, mindfulness, and mental health support

  • Family planning benefits, including fertility, adoption, and surrogacy support

  • Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown

  • Savings and investment opportunities to help you plan for the future

  • Location-specific perks and extras

The salary range for this role is $89,900.00 - $143,800.00. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An individual’s position within the salary range will be based on several factors including, but not limited to, specific competencies, relevant education, qualifications, certifications, experience, skills, performance, and business or organizational needs.

The successful candidate may be eligible for an annual discretionary bonus, other incentive compensation, or equity award, subject to company plan eligibility criteria and individual performance.

About Moderna

Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.  

By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities. 

We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. 

If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities. 

Our Working Model 

As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact. 

Moderna is a smoke-free, alcohol-free, and drug-free work environment. 

Equal Opportunities

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law.  Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!

Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements. 

Accommodations

We’re focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best. 

Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at [email protected]. 

Export Control Notice

This position may involve access to technology or data that is subject to U.S. export control laws, including the Export Administration Regulations (EAR). As such, employment is contingent upon the applicant’s ability to access export-controlled information in accordance with U.S. law. Due to the nature of the work and regulatory requirements, only individuals who qualify as U.S. persons (citizens, permanent residents, asylees, or refugees) are eligible for this position. For this role Moderna is unable to sponsor non-U.S. persons to apply for an export control license.

#LI-CK1

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Top Skills

Calorimetry
Elisa
Light Scattering
Liquid Chromatography
Mass Spectrometry
Next Generation Sequencing
Spectroscopy
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The Company
Cambridge, Massachusetts
6,848 Employees
Year Founded: 2010

What We Do

At Moderna, we believe messenger RNA, or mRNA, is the “software of life.”

Every cell in the body uses mRNA to provide real-time instructions to make the proteins necessary to drive all aspects of biology, including in human health and disease.

Given its essential role, we believe mRNA could be used to create a new category of medicines with significant potential to improve the lives of patients.

We are pioneering a new class of medicines made of messenger RNA, or mRNA. The potential implications of using mRNA as a drug are significant and far-reaching and could meaningfully improve how medicines are discovered, developed and manufactured.

To learn more, visit www.modernatx.com.

This Moderna page is not the appropriate place to report adverse events (side-effects) for any products. If you are or someone you know is experiencing a side effect, please reach out to your healthcare professional. Moderna is continuously monitoring the safety of its products. We encourage you to report any side effects directly to us at 1‑866‑MODERNA (1‑866‑663‑3762).

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