Principal Developer - Next Generation Sequencing - Translational Research, Innovation & Test Development Office (TRITDO)
Division/Departmental test development/innovation platform leader who develops, innovates, evaluates, and implements novel/new tests, methodologies, technologies, or products for the laboratory under the intellectual and scientific guidance of laboratory directors and senior principal developer. Test development/innovation platform leader responsible for development/innovation support of multiple projects across the division/department. Responsible for improvement of existing methods or implementation of novel technology of proven validity. Test development/innovation platform leader on cross-departmental teams, including Bioinformatics and IT, to create final recommendations to the laboratory directors and supervisors in the evaluation of novel laboratory equipment, instrumentation, procedures, and computer software and hardware. Test development/innovation platform leader and mentor for test development /innovation staff.
**This position is not eligible for visa sponsorship. Also, Mayo Clinic DOES NOT participate in the F-1 STEM OPT extension program**
We require a two year commitment to this role
QualificationsBachelor's degree in clinical/medical laboratory science (CLS/MLS), medical technology (MT), chemistry, biological science from an accredited institution or bachelor’s degree from an accredited institution in addition to a certificate in MLS. Six years of relevant laboratory experience; or a Master's degree from an accredited institution in chemical, physical, biological, clinical laboratory science or medical technology and four years of relevant laboratory experience; or a Doctoral degree in chemistry or a biological science and two years of relevant laboratory experience. A HEW certificate may be substituted for the specified degree. Other clinical laboratory specialty certificates will be reviewed and approved on a case-by-case basis. Master's degree or Doctoral (PhD) degree from an accredited institution in chemical, physical, biological, clinical laboratory science or medical technology preferred. Test development/innovation leader for multiple complex cross-area projects.
Additional Qualifications
- Demonstrated ability to work independently with a high degree of initiative, organization, and efficiency while exercising sound judgment, decision-making, and project management skills.
- Excellent written and verbal communication skills, with the ability to effectively collaborate across multidisciplinary teams.
- Proven ability to interpret and apply scientific literature, reference materials, and existing methodologies to develop and implement innovative laboratory methods, processes, or products.
- Adaptable and flexible in managing multiple projects involving diverse technologies, platforms, and scientific disciplines.
- Strong analytical, problem-solving, and scientific expertise with comprehensive knowledge of laboratory procedures and best practices.
- Extensive experience with Next Generation Sequencing (NGS) technologies, including assay development, optimization, validation, and data interpretation.
License or Certification:
ASCP or other certification pertinent to the laboratory field may be required depending on the laboratory specialty and prevailing regulatory requirements. Employees obtaining CT certification(s) after January 1, 2004 will be required to demonstrate evidence of ongoing maintenance of certification. Employees obtaining SCT certification(s) after January 1, 2006 will be required to demonstrate evidence of ongoing maintenance of certification.
About UsMayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
- Medical: Multiple plan options.
- Dental: Delta Dental or reimbursement account for flexible coverage.
- Vision: Affordable plan with national network.
- Pre-Tax Savings: HSA and FSAs for eligible expenses.
- Retirement: Competitive retirement package to secure your future.
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law". Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.
Skills Required
- Bachelor's degree in clinical or medical laboratory science, medical technology, chemistry, biological science, or a related accredited degree plus MLS certificate
- Six years of relevant laboratory experience with a qualifying bachelor's degree
- Alternatively, a qualifying master's degree plus four years of relevant laboratory experience
- Alternatively, a qualifying doctoral degree in chemistry or biological science plus two years of relevant laboratory experience
- HEW certificate may substitute for the specified degree
- Experience leading multiple complex cross-area test development or innovation projects
- Strong written and verbal communication skills and multidisciplinary collaboration ability
- Ability to interpret scientific literature and develop or implement innovative laboratory methods, processes, or products
- Strong analytical, problem-solving, scientific, project management, and decision-making skills
- Extensive experience with Next Generation Sequencing technologies, including assay development, optimization, validation, and data interpretation
- Master's or doctoral degree in chemical, physical, biological, clinical laboratory science, or medical technology
- ASCP or other pertinent laboratory certification, depending on specialty and regulatory requirements
Mayo Clinic Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Mayo Clinic and has not been reviewed or approved by Mayo Clinic.
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Retirement Support — A no-cost pension plus an employer-matched 403(b)/401(k) is positioned as a standout differentiator, offering strong long-term financial security. Feedback suggests this retirement combination elevates overall total rewards even when base pay is moderate.
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Healthcare Strength — Expanded medical networks, enhanced fertility coverage, and employer absorption of a plan year’s premium increases point to robust healthcare offerings. Feedback suggests annual updates maintain breadth and competitiveness of coverage.
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Parental & Family Support — Adoption assistance, dependent scholarships, child and elder-care resources, and EAP services provide meaningful family-oriented support. Feedback suggests these programs add tangible value beyond salary alone.
Mayo Clinic Insights
What We Do
Mayo Clinic is the first and largest integrated, not-for-profit medical group practice in the world. Doctors from every medical specialty work together to care for patients, joined by common systems and a philosophy of "the needs of the patient come first." More than 3,800 physicians and scientists and 50,900 allied health staff work at Mayo Clinic, which has sites in Rochester, Minn., Jacksonville, Fla., and Scottsdale/Phoenix, Ariz. Mayo Clinic also serves over 70 communities through Mayo Clinic Health System with locations in MN, IA, and WI. Collectively, these locations care for more than 1 million people each year.







