Principal Associate Scientist, Analytical Operations

Company Overview:

Strand Therapeutics is a clinical stage biotechnology company utilizing synthetic biology to genetically program mRNA to deliver truly revolutionary immunotherapies to patients.

Building on the idea of creating smart therapies based on Boolean logic circuits, Strand was started by biological engineers working together at MIT who were seeking to apply the concept of the emerging field of mRNA therapeutics. Strand's technology is therapeutic-area and mRNA modality agnostic where therapeutic proteins are encoded onto modified, self-replicating, or circular mRNA backbones which in turn are programmed with cell-specific sensors and circuits.

Today, Strand has established three platforms with one clinical stage asset and several programs in preclinical development as well as early discovery. Our lead program, STX-001, is currently being evaluated in a phase 1 clinical trial for solid tumors. Our corporate headquarters is located in the Fenway district of Boston, Massachusetts.

Become the next standout single strand!

Job Summary:

Strand is looking for people who have the enthusiasm and motivation to be a highly contributing member of a small but extremely productive team. This opportunity will offer the employee the ability to work in a matrix-based environment and be a part of the future strategy of the company.

We are looking for a highly motivated and innovative candidate for the role of Principal Associate Scientist of Analytical Operations. This individual will lead day-to-day analytical operations as an analyst as well as a people manager within the analytical core. Reporting to the Senior Scientist of Analytical Development, the right candidate will be a strategic thinker that brings a leadership presence and enthusiasm for Strand along with a deep scientific knowledge.

Primary Responsibilities:

• Responsible for analyzing internally and externally submitted samples with various analytical methods (cell-based assays, ELISA’s, RT-PCR, LC-MS, etc.).
• Assist in optimization/troubleshooting of existing methods for use in current and future programs.
• Use various statistical tools to analyze and independently draw conclusions about data.
• Analytically support screening, optimization, and scale-up efforts in mRNA and LNP Process Development.

Qualifications:

• B.S. with at least 5-6+ years of relevant experience or M.S. with at least 4+ years of relevant experience with an educational focus in Chemical Engineering, Bioengineering or similar preferred.
• Working experience in analytical development operations pertaining to biologics required.
• Prior experience with LNPs with nucleic acid payloads highly preferred.
• Experience with analytical methods such as cell-based assays, ELISA’s, RT-PCR and/or LC-MS required.
• Prior experience with people management, mentorship and/or development highly preferred.
• Strong collaboration and inter-personal skills.
• Ability to multi-task and prioritize to meet important deadlines.

Strand offers a fast-paced, entrepreneurial, team-focused small company environment. We also offer a top-notch benefits package (health, dental, life, open PTO, onsite lunch catering, commuter support and more) and work/life flexibility and integration. Being part of the Strand team allows you to become part of a small team that supports professional development while working together to meet Strand’s goals. 

Strand Therapeutics is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law. Strand does not accept unsolicited resumes from any source other than directly from candidates.

Job Type: Full-time

Salary: commensurate with role and experience