[Pfizer] Senior Manager, AI Infrastructure and Operations

Sorry, this job was removed at 06:09 p.m. (UTC) on Wednesday, Mar 04, 2026
Be an Early Applicant
Tokyo, JPN
Hybrid
Artificial Intelligence • Healthtech • Machine Learning • Natural Language Processing • Biotech • Pharmaceutical
We’re in relentless pursuit of breakthroughs that change patients’ lives.
The Role
ROLE SUMMARY
The Sr. Manager/Staff Engineer, AI Infrastructure & MLOps Engineering is a senior technical leader responsible for architecting, building, and scaling Pfizer's AI infrastructure and developer platforms. This role leverages extensive experience in cloud engineering, DevOps, and MLOps to deliver robust, high-performance solutions supporting advanced AI/ML workloads in biotechnology, healthcare, and enterprise technology. The successful candidate will drive innovation in automation, reliability, and scalability, enabling scientists and engineers to rapidly develop, deploy, and monitor machine learning models in production environments.
ROLE RESPONSIBILITIES
Platform Architecture & Engineering
  • Design, implement, and own large-scale cloud-based HPC and MLOps platforms supporting AI model training, genomic sequencing, and precision medicine.
  • Architect multi-environment clusters (AWS, GCP, Azure), enabling GPU/FPGA workloads and advanced observability.
  • Lead the development of developer and cloud platforms, including internal engineering accelerators and reusable toolsets.

Platform Catalog & Developer Experience
  • Design, implement, and manage unified platform catalogs using Backstage, enhancing developer experience and application metadata management.
  • Develop custom plugins and APIs for Backstage to support internal engineering workflows and documentation.

Automation & DevOps Excellence
  • Build and maintain Python-based automation frameworks, CI/CD pipelines, and Infrastructure-as-Code (Terraform, Helm, Pulumi, AWS CDK).
  • Operationalize containerized solutions using Docker and Kubernetes, integrating MLflow, Kubeflow, and other orchestration platforms.
  • Implement robust automation for provisioning, configuring, and managing cloud resources across multiple environments.

MLOps & Reliability Engineering
  • Lead the implementation of Service Level Indicators (SLIs), Service Level Objectives (SLOs), and advanced observability (Prometheus, Grafana, PagerDuty).
  • Develop and maintain APIs and services for model management, feature stores, and inference pipelines.
  • Operationalize ML model serving at scale using frameworks such as TensorFlow Serving, TorchServe, KServe, and Seldon Core.
  • Ensure compliance with industry standards (e.g., HIPAA, FDA) for data protection and reliability.

Collaboration & Leadership
  • Mentor engineers and lead cross-functional teams to deliver integrated solutions.
  • Champion engineering excellence through design documentation, code reviews, and testing automation.
  • Present at industry summits, author technical proposals, and contribute to open-source projects (Kubernetes, Helm, Go, Envoy).

Continuous Improvement
  • Drive agile delivery, sprint planning, and performance optimization.
  • Lead incident response and disaster recovery initiatives for mission-critical platforms.
  • Foster a culture of shared ownership, transparency, and innovation

BASIC QUALIFICATIONS
  • 8+ years of hands-on software engineering experience in cloud infrastructure, DevOps, and MLOps.
  • Deep expertise in Python, Kubernetes, Terraform, Helm, and CI/CD pipeline development.
  • Proven experience architecting and operating containerized solutions on AWS, GCP, and Azure.
  • Strong knowledge of Infrastructure-as-Code, distributed systems, and production system reliability.
  • Bachelor's or Master's degree in Computer Science, Engineering, or related field.

PREFERRED QUALIFICATIONS
  • Expertise in AWS cloud services (EC2, S3, Lambda, EKS, SageMaker, API Gateway, CloudFormation, IAM, etc.).
  • Experience deploying and customizing Backstage as a unified catalog for teams, services, and technical documentation.
  • Experience building and deploying microservices and REST/gRPC APIs for AI model delivery.
  • Familiarity with MLflow, Kubeflow, and other MLOps orchestration platforms.
  • Proficiency with model serving frameworks (TensorFlow Serving, TorchServe, KServe, Seldon Core, BentoML, etc.).

Work Location Assignment: Tokyo HQ
Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.
Information & Business Tech

What the Team is Saying

Daniel
Anna
Esteban
Pfizer

Pfizer Compensation & Benefits Highlights

  • Healthcare Strength Multiple U.S. medical plan options include telehealth, comprehensive mental‑health support, fertility/family‑building benefits, transgender‑inclusive coverage, and certain Pfizer medications at no cost. A Wellbeing Wallet and wellness resources broaden the health and wellbeing offering.
  • Retirement Support A 401(k) with company matching is paired with an additional Pfizer Retirement Savings Contribution, alongside company‑paid life and disability insurance. One‑on‑one financial planning support is provided through Fidelity.
  • Leave & Time Off Breadth Paid time off spans vacation, holidays, and personal days, with additional caregiver and medical leave. U.S. parental leave commonly includes 12 weeks paid with options for additional unpaid bonding time and a return‑to‑work transition.

Pfizer Insights

Similar Jobs

Pfizer Logo Pfizer

Scientist

Artificial Intelligence • Healthtech • Machine Learning • Natural Language Processing • Biotech • Pharmaceutical
In-Office
Tokyo, JPN
121990 Employees

Pfizer Logo Pfizer

Scientist

Artificial Intelligence • Healthtech • Machine Learning • Natural Language Processing • Biotech • Pharmaceutical
In-Office
Tokyo, JPN
121990 Employees

Pfizer Logo Pfizer

[R&D] スタディマネジャー/Japan Study Manager

Artificial Intelligence • Healthtech • Machine Learning • Natural Language Processing • Biotech • Pharmaceutical
Hybrid
Tokyo, JPN
121990 Employees

Pfizer Logo Pfizer

[R&D] スタディマネジャー/Japan Study Manager

Artificial Intelligence • Healthtech • Machine Learning • Natural Language Processing • Biotech • Pharmaceutical
In-Office
Tokyo, JPN
121990 Employees
Get Personalized Job Insights.
Our AI-powered fit analysis compares your resume with a job listing so you know if your skills & experience align.

The Company
HQ: New York, NY
121,990 Employees
Year Founded: 1848

What We Do

Our purpose ensures that patients remain at the center of all we do. We live our purpose by sourcing the best science in the world; partnering with others in the healthcare system to improve access to our medicines; using digital technologies to enhance our drug discovery and development, as well as patient outcomes; and leading the conversation to advocate for pro-innovation/pro-patient policies.

Why Work With Us

We are the inventors, the problem solvers, the big thinkers — those who surmount any hurdle to deliver breakthrough medicines to the people who are counting on them the most.

Gallery

Gallery
Gallery
Gallery
Gallery
Gallery

Pfizer Offices

Hybrid Workspace

Employees engage in a combination of remote and on-site work.

Typical time on-site: 2.5 days a week
Company Office Image
HQHudson Yards
Provincia de Buenos Aires
Andover, MA
Athens, GR
Chennai, IN
Collegeville, PA
Durham, NC
Groton, CT
Madison, NJ
Madrid, ES
Mumbai, Maharashtra
Rochester, MI
San Diego, CA
Seattle, WA
Company Office Image
Tampa, FL
Center for Digital Innovation
Learn more

Sign up now Access later

Create Free Account

Please log in or sign up to report this job.

Create Free Account