GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured.

Supply Chain Manager (Supply Planning) at GRAIL

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GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is headquartered in Menlo Park, CA with locations in Washington, D.C., North Carolina, and the United Kingdom. GRAIL, LLC is a wholly-owned subsidiary of Illumina, Inc. (NASDAQ:ILMN). For more information, please visit

The Supply Planning Manager will ensure materials required to detect cancer are available at the right time, place, and cost. The Supply Planning Manager performs all aspects of supply planning through execution, including both internal manufactured and externally procured material. This individual will be responsible for developing production/supply plans that consider forecasts, availability of material and manufacturing capacity. The candidate is responsible for identifying and maintaining the appropriate planning parameters in ERP systems to optimize material supply plans. The individual will also be required to provide materials to manufacturing areas based on planned production schedules. Under the direction of the Sr. Director, Supply Chain, this role will develop supply strategies to enable successful product development and commercialization at GRAIL.

You will:

  • Use solid understanding of supply chain fundamentals to forecast and manage inventory levels.
  • Continuously improve and support the GRAIL material forecast and planning model.
  • Provide proactive scheduling signals and daily technical support for the Reagent Manufacturing team.
  • Drive planning process and tools with suppliers and contract manufacturers to manage capacity availability, supply visibility, lead time and exceptions.
  • Provide clear order signals to enable purchase order placement. Ensure right product, right quantity on time and meeting specifications.
  • Partner with Procurement team to perform supply risk assessments, and implement inventory strategies to mitigate impact.
  • Develop material allocation process and rules to manage supply constraints or shortages.
  • Troubleshoot transactional records to resolve inventory discrepancies.
  • Partner with Finance team to maintain the materials and consumables budget.
  • Manage long and short-term excess and obsolescence plan for materials.
  • Develop and maintain Key Performance Indicators for Supply Planning.
  • Support development of Enterprise Resource Planning (ERP) tool to more effectively forecast, complete purchases, and track supply chain health.
  • Identify improvement opportunities in the material planning process, marshal resources, and drive projects to completion.
  • Manage planning parameters and master data to optimally reflect supply chain capabilities.
  • Participate in weekly S&OP process.
  • Monitor weekly/monthly production plan attainments to ensure continuous product supply to prevent supply interruption to the internal and external customer.
  • Proactively communicate product availability updates to all levels of the Supply Chain and other Lab Operations teams including potential inventory risks.
  • Support analysis and scenario planning exercises to identify potential gaps and opportunities to improve supply plans, and internal delivery mechanisms.

Your background and qualifications will include:

  • B.S required, advanced degree or certification (CSCP, CPIM, CPSM) desirable.
  • 10+ years working experience in supply chain or manufacturing function.
  • 5+ years of production planning, materials planning, and/or related experience.
  • Life Sciences background preferred
  • Demonstrated ability to work in a complex, fast-paced, changing environment.
  • Proficiency in spreadsheet model building and troubleshooting.
  • Analytical and planning skills associated with optimizing a production schedule.
  • Knowledge of commonly used concepts, practices, and procedures within cGMP reagent manufacturing.
  • Demonstrated understanding of inventory control and electronic MRP systems and intermediate proficiency using Excel and other Microsoft applications.
  • In‐depth knowledge of ERP or MRP software preferred, NetSuite experience is a plus.
  • Ability to interact well with internal and external partners and/or customers.
  • Ability to communicate clearly and effectively and have excellent attention to detail, interpersonal, and multitasking skills.
  • Excellent teamwork, communication, and collaboration skills as evidenced by ability to build rapport and credibility quickly.
  • Demonstrated ability to develop ad-hoc tools/processes as needed in a start-up environment.
  • Excellent attention to detail, but with a keen awareness of the big picture.
  • Proven experience in life sciences industry desirable, but not required.
  • Knowledge of cGMP/FDA regulated industry is preferred.

GRAIL is an Equal Employment Office and Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status. We will reasonably accommodate all individuals with disabilities so that they can participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Following extensive monitoring, research, consideration of business implications, and advice from internal and external experts, GRAIL has made the decision to require all U.S. employees receive the COVID-19 vaccines as a condition of employment. “Full vaccination” is defined as two weeks after both doses of a two-dose vaccine or two weeks since a single-dose vaccine has been administered. Anyone unable to be vaccinated, either because of a sincerely held religious belief or a medical condition or disability that prevents them from being vaccinated, can request a reasonable accommodation.

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Technology we use

  • Engineering
  • Sales & Marketing
    • C++Languages
    • GolangLanguages
    • JavascriptLanguages
    • PythonLanguages
    • RLanguages
    • SqlLanguages
    • ReactLibraries
    • AWSLibraries
    • S3Libraries
    • EC2Libraries
    • GitLibraries
    • KubernetesFrameworks
    • DockerFrameworks
    • ProtobufFrameworks
    • BazelFrameworks
    • PhabricatorFrameworks
    • MongoDBDatabases
    • MySQLDatabases
    • RedisDatabases
    • SQLiteDatabases
    • SalesforceCRM

What are GRAIL Perks + Benefits

GRAIL Benefits Overview

We’re committed to creating the best experience for everyone at GRAIL, ensuring that each member of our team has comprehensive benefits and resources to thrive at all stages of life, both at work and at home.

Friends outside of work
Eat lunch together
Intracompany committees
Daily sync
Open door policy
Team owned deliverables
Team based strategic planning
Group brainstorming sessions
Open office floor plan
Dedicated Diversity/Inclusion Staff
Unconscious bias training
Diversity manifesto
Mean gender pay gap below 10%
Diversity Employee Resource Groups
Hiring Practices that Promote Diversity
Health Insurance & Wellness Benefits
Flexible Spending Account (FSA)
Disability Insurance
Dental Benefits
Vision Benefits
Health Insurance Benefits
Life Insurance
Wellness Programs
Onsite Gym
Team workouts
Retirement & Stock Options Benefits
Company Equity
Performance Bonus
Child Care & Parental Leave Benefits
Child Care Benefits
Generous Parental Leave
Flexible Work Schedule
Remote Work Program
Family Medical Leave
Company sponsored family events
Vacation & Time Off Benefits
Unlimited Vacation Policy
Paid Holidays
Paid Sick Days
Perks & Discounts
Casual Dress
Commuter Benefits
Free Daily Meals
Game Room
Happy Hours
Professional Development Benefits
Job Training & Conferences
Diversity Program
Cross functional training encouraged
Promote from within
Mentorship program
Online course subscriptions available

An Insider's view of GRAIL

How does your team reward individual success?

People grow their skills both by learning how to rapidly build scalable software systems, but also by partnering with scientists and other domain experts to better understand, model, and envision the systems we will need. We enable and empower our engineers to lead this process and grow with our systems as they make the future of GRAIL a reality.

Tristan Matthews

Senior Director, Software Engineering

What projects are you most excited about?

GRAIL has a unique opportunity to scale our operations to add value with our early detection test. Our automation team works on the full spectrum of projects from low-level instrument investigations to overall architectures of processing facilities. I'm excited by projects that push the boundaries of lab automation, and that's what GRAIL is doing.

David Jenions

Principal Automation Engineer

What does career growth look like on your team?

Our mission, to detect cancer early, is truly seeking a needle in many haystacks. Our lab has a very complex and sophisticated assay to execute. We leverage cross-training and mentorship programs where new teammates learn the ropes from senior staff. My team sets people up for success by turning tasks into learning opportunities.

Maryam Hosseini

Director, Laboratory Operations

How do your team's ideas influence the company's direction?

The biological problem we're trying to solve is a complex machine learning problem with human lives at stake. From a software engineering point of view, taking massive data, organizing it, building tools to mine it, and deliver results in a scalable, secure, and clinically compliant manner are areas of innovation. This, for me, is my dream job!

Satnam Alag

SVP, Software Engineering

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