Master Thesis AI Based Prediction for Anatomical Motion Modelling on Unity

Posted 3 Days Ago
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Stockholm, SWE
In-Office
Entry level
Healthtech • Biotech
The Role
Master’s thesis investigating AI-based prediction of anatomical motion on the Elekta Unity MR-Linac platform. The student will curate motion datasets, benchmark the existing prediction algorithm, develop and train an AI model for clinically relevant prediction horizons, and compare performance using quantitative metrics. Deliverables include a curated dataset, prototype software, reproducible pipelines, documentation, a written report, and presentation.
Summary Generated by Built In
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We don’t just build technology. We build hope for everyone dealing with Cancer.

Elekta is shaping the standard of care, together with healthcare providers, by developing precision radiation medicine that brings advanced radiotherapy into routine clinical practice. Our solutions support consistent, efficient and personalized care, addressing evolving patient needs. Through adaptive radiotherapy, precision treatment delivery and integrated workflows, Elekta supports care teams across a range of clinical settings. Each year more than 2 million patients are treated using Elekta solutions across over 130 countries. Elekta is headquartered in Stockholm, Sweden, with over 4,000 employees and offices in more than 40 countries. The company is listed on Nasdaq Stockholm. For more information, visit elekta.com.

Introduction 

Radiotherapy targets and surrounding anatomy can move during treatment. The Elekta Unity combines an MR scanner with a linear accelerator, enabling anatomy to be visualised during radiation delivery and allowing treatment adaptation based on real-time information. However, there are inherent latencies associated with image acquisition, image processing, data transfer, and motion estimation. To compensate for these latencies, future anatomical motion must be predicted. This project will investigate whether an AI-based approach can improve prediction accuracy at extended prediction horizons. 


Background 

Radiotherapy treatments are designed with millimeter precision to ensure that high doses of radiation can be delivered to the target while sparing surrounding healthy tissues and critical anatomical structures. However, both the target and surrounding anatomy may move during treatment due to physiological processes such as respiration, peristalsis, and organ drift. The Elekta Unity can visualise and respond to this motion in real time, improving dosimetric accuracy and therefore improving patient outcomes. 


The current Automatic Position Management (APM) framework acquires an orthogonal pair of 2D cine images at a rate of 5 Hz. Each image is compared with a reference image using rigid registration to estimate target motion. A prediction engine then extrapolates the observed motion to estimate the target position once all processing steps have been completed. 


In the future, longer prediction horizons may be required to support more advanced image acquisition strategies, target-tracking approaches, or dose-based interventions. To enable these developments, a prediction algorithm must maintain accuracy while predicting further into the future. AI methods such as recurrent neural networks have shown promise for time-series prediction tasks both within and beyond radiation oncology and will therefore form the primary focus of this investigation. 


Problem Statement 

 

The project will investigate the suitability of AI approaches for motion prediction on the Unity platform through the following objectives: 

  • Curate a dataset of target centroid motion from a range of anatomies influenced by respiratory motion using a combination of publicly available datasets and historical MR-Linac treatment data. 
  • Establish a benchmark by evaluating the curated dataset using the currently implemented prediction algorithm. 
  • Choose a suitable AI model to predict centroid motion at clinically relevant prediction horizons. Adapt the model and train on the data collected. 
  • Compare the performance of the proposed approach against the existing prediction algorithm using appropriate quantitative metrics. 

 

Output 

 

  • An assessment of the potential benefits of incorporating AI-based motion prediction within the APM framework 
  • A curated motion dataset that can support future research and development activities. 
  • Prototype software, reproducible processing pipelines, and documentation. 
  • A written report and final presentation 

Who are we looking for? 

We are looking for a master’s student in medical physics, computer science, applied mathematics, engineering physics, or a related scientific discipline.  

 

Required profile:  

  • Programming experience and the ability to work independently on an exploratory research problem.  
  • A strong scientific or engineering background, including confidence with quantitative analysis.  

Desirable experience:  

  • Experience in medical image processing, ideally in Python 
  • Experience with AI / deep learning methods 
  • Familiarity with radiotherapy, especially the MR-Linac 

Practicalities 

Location: Elekta office, Stockholm 

Supervisor: Ned Goodwin 

Start date: Flexible 

Skills Required

  • Currently pursuing a master's degree in medical physics, computer science, applied mathematics, engineering physics, or a related scientific discipline
  • Programming experience
  • Ability to work independently on an exploratory research problem
  • Strong scientific or engineering background
  • Confidence with quantitative analysis
  • Experience with medical image processing, ideally in Python
  • Experience with AI or deep learning methods
  • Familiarity with radiotherapy, especially MR-Linac systems

Elekta Compensation & Benefits Highlights

The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Elekta and has not been reviewed or approved by Elekta.

  • Retirement Support — A 401(k) with employer match is a prominent benefit, with vesting noted as part of the plan.
  • Leave & Time Off Breadth — PTO and paid holidays are included, with PTO accruing from the start and rollover allowed within limits.
  • Healthcare Strength — Medical, dental, vision, life and disability coverage are included, complemented by an Employee Assistance Program.

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The Company
HQ: Stockholm
4,700 Employees
Year Founded: 1972

What We Do

At Elekta, our outcome-driven and cost-efficient solutions provide lasting clinical difference and are developed through sustainable environmental, social and governance practices. We’ve been working openly and proactively with clinicians and our partners for almost half a century to advance precision radiation therapy and meet continuously evolving patient needs—no matter where they are in the world. To us, it's personal, and our global team of 4,700 employees combine passion, science, and imagination to profoundly change cancer care. We don’t just build technology, we build hope. Elekta is headquartered in Stockholm, Sweden, with offices in 120 countries and listed on Nasdaq Stockholm.

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