The Role
The Supply Chain Manager will oversee O2C processes, manage logistics and distribution, and enhance supply chain performance compliance with regulations.
Summary Generated by Built In
Company Overview
Rhythm is a global, commercial-stage biopharmaceutical company committed to transforming the lives of patients and their families living with rare neuroendocrine diseases. We develop medicines for previously untreatable or undertreated diseases and provide meaningful support for healthcare providers and patients and their families. We recognize the courage it takes for patients and their caregivers to begin their journey of advocacy to find the answers they need. Their courage inspires us to challenge convention, ask bold questions and seek answers for them. Every day, we strive for excellence through our willingness to adapt, learn, and our tenacity to overcome barriers, together.
Opportunity Overview
As a Supply Chain Manager, you will lead the day-to-day operations/transactions of the Global Supply Chain with the main focus on order-to-cash aspect. The scope of responsibilities includes management and oversight of third-party logistics, customer service and distribution, whilst operating in accordance with GMP/GDP guidelines. In this role, you will be an integral part of a dynamic Technical Operations team and collaborate closely with other departments as needed (Finance, Commercial, Legal, etc.). If you enjoy both visibility and accountability that come with joining a growing organization, you will thrive in this opportunity.
Responsibilities and Duties
Qualifications and Skills
More about Rhythm
We are a dynamic and growing global team spanning more than a dozen countries. At Rhythm we are dedicated to transforming the lives of patients living with rare neuroendocrine diseases by rapidly advancing care and precision medicines that address the root cause. Our team is passionate about expanding access to reach more patients and developing novel therapies for other rare neuroendocrine diseases, including congenital hyperinsulinism.
At Rhythm our core values are:
Rhythm is a global, commercial-stage biopharmaceutical company committed to transforming the lives of patients and their families living with rare neuroendocrine diseases. We develop medicines for previously untreatable or undertreated diseases and provide meaningful support for healthcare providers and patients and their families. We recognize the courage it takes for patients and their caregivers to begin their journey of advocacy to find the answers they need. Their courage inspires us to challenge convention, ask bold questions and seek answers for them. Every day, we strive for excellence through our willingness to adapt, learn, and our tenacity to overcome barriers, together.
Opportunity Overview
As a Supply Chain Manager, you will lead the day-to-day operations/transactions of the Global Supply Chain with the main focus on order-to-cash aspect. The scope of responsibilities includes management and oversight of third-party logistics, customer service and distribution, whilst operating in accordance with GMP/GDP guidelines. In this role, you will be an integral part of a dynamic Technical Operations team and collaborate closely with other departments as needed (Finance, Commercial, Legal, etc.). If you enjoy both visibility and accountability that come with joining a growing organization, you will thrive in this opportunity.
Responsibilities and Duties
- Own and lead the end-to-end Order to Cash (O2C) process for the Global Supply Chain, ensuring timely, accurate, and compliant execution from order receipt through invoicing, revenue recognition, cash collection, and reconciliation.
- Act as the primary Supply Chain interface to Finance, Global Affiliates, Commercial, and external partners, ensuring alignment on orders, invoicing, revenue recognition, dunning, and cash application topics.
- Ensure accurate, timely, and compliant invoicing and documentation, supporting correct revenue recognition and financial close activities in close collaboration with Finance.
- Drive active, accurate, and insightful supply chain reporting for internal stakeholders, including inventory, sales reconciliation, order fulfillment, billing status, cash collection, and KPI performance.
- Lead sales and inventory reconciliation activities, investigating variances, resolving root causes, and ensuring data integrity across ERP, 3PL, and financial systems.
- Manage and continuously improve 3PL performance, including order processing, distribution execution, inventory accuracy, invoice validation, and resolution of aged or disputed invoices.
- Identify, design, and implement system and process improvements across O2C, distribution, and reporting to enhance efficiency, visibility, scalability, and supply chain resilience.
- Execute and oversee ERP transactions (e.g., sales orders, transfer orders, invoicing, inventory movements, packaging lists), ensuring accuracy, compliance, and audit readiness.
- Ensure all operational activities are performed in compliance with GMP/GDP and SOX requirements, maintaining robust internal controls, documentation, and audit support.
- Proactively manage stakeholder communication, escalating risks, constraints, or financial impacts related to supply chain execution and O2C performance.
- Contribute to the development of standard operating procedures (SOPs), work instructions, and control documentation, supporting a scalable and compliant global supply chain organization.
Qualifications and Skills
- 5+ years of experience managing global pharmaceutical supply with relevant management experience
- Bachelor’s degree in supply chain management, procurement, engineering, operations, finance or business administration preferred, an advanced degree preferred
- Must be based in the Netherlands
- Strong analytical ability
- Flexibility to work in different time zones
- Proven ability to develop process driven solutions
- Ability to take a leadership role and drive quality progress
- Willingness and capability to handle multiple projects and responsibilities within the time constraints
- ERP experience – Dynamics 365, SAP or Oracle preferred
- Ability to successfully work both within a team and independently
- Excellent written and verbal communication skills
More about Rhythm
We are a dynamic and growing global team spanning more than a dozen countries. At Rhythm we are dedicated to transforming the lives of patients living with rare neuroendocrine diseases by rapidly advancing care and precision medicines that address the root cause. Our team is passionate about expanding access to reach more patients and developing novel therapies for other rare neuroendocrine diseases, including congenital hyperinsulinism.
At Rhythm our core values are:
- We are committed to advancing scientific understanding to improve patients’ lives
- We are inspired to tackle tough challenges and have the courage to ask bold questions
- We are eager to learn and adapt
- We believe collaboration and ownership are foundational for our success
- We value the unique contribution each individual brings to furthering our mission
Skills Required
- 5+ years of experience managing global pharmaceutical supply
- Bachelor's degree in supply chain management, procurement, engineering, operations, finance or business administration preferred
- ERP experience - Dynamics 365, SAP or Oracle
- Strong analytical ability
- Excellent written and verbal communication skills
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The Company
What We Do
Rhythm is a biopharmaceutical company aimed at developing and commercializing therapies for the treatment of rare genetic diseases of obesity. The company is leveraging the Rhythm Engine -- comprised of its TEMPO Registry, GO-ID genotyping study and Uncovering Rare Obesity program -- to improve the understanding, diagnosis and potentially the treatment of these disorders. For healthcare professionals, visit www.RareObesity.com for more information. For patients and caregivers, visit www.LEADforRareObesity.com for more information.
