Manager, Strategy & Business Operations

Sorry, this job was removed at 06:21 p.m. (CST) on Friday, May 15, 2026
San Mateo, CA, USA
Hybrid
Healthtech • Biotech
The Role
Who We Are & What We Do 
At Helix, our mission is simple: to help everyone improve their lives through their DNA.

Ready to make a real-world impact with your skills? At Helix, we're transforming healthcare by making genomics a standard of care. We partner with health systems and life science companies to accelerate the integration of genomic data into clinical practice. Join us in building a future where healthcare is personalized, proactive, and powered by genomics. 

What is special about this role:
The Strategy & Business Operations team is the swiss-army knife of Helix. We help define, scope, and operationalize critical initiatives across the business. As part of a small team that works closely with the leadership team, you will be at the center of the inner workings of how a company makes both strategic and operational decisions to help bring a shared vision to life. You will get your hands dirty across multiple functional areas – from Business Development and Finance, to Product and Science, and more. This is a great opportunity for a self-starter with a strong foundation in healthcare, is energized by the unknown, and thrives in a fast-paced environment.

As a Manager, Strategy & Business Operations you will:
  • Work closely with the leadership team to identify, develop, and implement high-priority, strategic initiatives
  • Provide strategic insight to complex, cross-functional efforts to ensure alignment with business priorities
  • Leverage data and business insights to pinpoint operational needs and recommend process improvements
  • Spearhead the development and execution against detailed project plans to support successful launches
  • Conduct market research to validate hypotheses and identify opportunities to accelerate growth
  • Support the evaluation of strategic opportunities (e.g. partnerships, acquisitions, etc.)
  • Contribute to the development of Board meeting materials and investor presentations
  • Act as a key resource in resolving critical and time-sensitive challenges facing the business

About you:
  • BA or BS degree
  • 4–6 years of experience in consulting, business operations, corporate strategy, or similar role at a high-growth startup; experience in health tech industry preferred
  • Proven track record of delivering results, even when outside past expertise
  • Strategic, structured problem-solver who can break down ambiguous asks into concrete plans
  • Ability to operate autonomously and influence stakeholders at all levels
  • Capable of owning the details, while still keeping the big picture in mind
  • Adaptable to shifting priorities, but can bring stability to a dynamic environment
  • Excellent interpersonal and communication skills, both written and verbal
  • Ability to tell a story focused on insights and data, not just a summary of data alone
  • Have a knack for learning new things fast
  • Highly proficient with G Suite (Sheets, Docs, Slides), macOS

Pluses:
  • Experience with Tableau, Thoughtspot, Hubspot
  • Experience working with health systems or payers

Expected Interview Process:
1) Recruiter Screen 2) Manager Screen 3) Virtual Onsite 4) Offer 

Expected Pay For This Role:
There are 3 distinct parts to your Helix offer: 1) Base Salary 2) Annual Bonus 3) Equity 
  • Expected Helix Base: $109,000 - $148,000
  • Expected Helix Discretionary Annual Bonus: 10% of your annual salary
  • Equity: We offer generous equity at Helix. If you receive a Helix offer your recruiter will book dedicated time with you to educate you on our equity model.

Aside from working alongside brilliant, dedicated, passionate, down-to-earth, curious, warm, and thoughtful people, we also provide great benefits:
  • Comprehensive Health Insurance with Date of Hire eligibility 
    • Above average employer paid premium coverage 
  • 12 weeks Helix Paid Parental Leave option 
  • 401(k) with employer matching of up to 3% and 100% Vesting on the Date of Hire
  • Comprehensive Well-Being Benefits 
  • Flexible PTO
  • Home office stipend 

Helix is proud to be an equal opportunity employer, and committed to providing employment opportunities regardless of race, religious creed, color, national origin, ancestry, physical disability, mental disability, medical condition, genetic information, marital status, sex, gender, gender identity, gender expression, pregnancy, childbirth and breastfeeding, age, sexual orientation, military or veteran status, or any other protected classification, in accordance with applicable federal, state, and local laws.

 #LI-Onsite

Helix Compensation & Benefits Highlights

The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Helix and has not been reviewed or approved by Helix.

  • Leave & Time Off Breadth Feedback suggests generous PTO, flexible time away, unlimited vacation, paid sick days, and paid parental leave support work–life balance. These policies are frequently highlighted alongside flexible scheduling.
  • Healthcare Strength Feedback suggests medical, dental, and vision coverage are complemented by a wellness program. Access to health-focused initiatives contributes to a comprehensive core benefits package.
  • Wellbeing & Lifestyle Benefits Feedback suggests commuter benefits, free daily meals, and onsite parking enhance day‑to‑day experience. Such perks, combined with flexible work arrangements, add lifestyle value beyond base pay.

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The Company
HQ: San Mateo, CA
200 Employees
Year Founded: 2015

What We Do

Helix is a rapidly growing startup focused on personal genomics. Helix has a simple but powerful mission: to empower every person to improve their life through DNA. We’re creating an ecosystem where people can explore diverse and uniquely personalized applications provided by high-quality partners.

Why Work With Us

We are collaborators—scientists, engineers, designers, marketers, and more—working across four offices to solve complex challenges locked within the human genome. We are biased toward action as we strive to uphold integrity in sequencing, science, and communication. At Helix, transparency, collaboration, and empowerment drive us in all that we do.

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