Lead IT Engineer, End User Computing & Lab IT

What if the work you did every day could impact the lives of people you know? Or all of humanity?

At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.

Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible.

Location

San Diego, CA. 100% onsite.

Must currently reside in the San Diego metropolitan area or be able to commute independently. No relocation assistance is available for this role.

Position Summary

The Lead IT Engineer for End User Computing & Lab IT will server a critical role within our global organization.  This position is based in our San Diego office and reports directly to the Senior IT Manager of End User Computing & Lab IT.

In this role, you will be responsible for a broad range of IT functions, including system design, analysis, evaluation, testing, debugging, and the implementation of repairs, upgrades and modification.  You will also diagnose and resolve technical issues to maintain optimal system performance. Additionally, you will oversee enterprise infrastructure platforms to identify performance concerns and ensure system integrity. Your responsibilities will include leading the planning and execution of business challenges analyses, leveraging automated system solutions to drive operational efficiency.

You will provide advanced engineering support and administration for managed endpoint platforms and services, including Intune, SCCM, and Jamf. This role also includes supporting endpoint provisioning and lifecycle management across manufacturing and lab environments.  The ideal candidate will have hands-on experience in designing, developing and maintaining automated deployment pipelines that ensure consistent configuration, security compliance and operational efficiency across diverse enterprise and specialized IT settings.

This position plays a vital role within the Global IT End User Computing team, contributing to the shared responsibility for maintaining system availability and ensuring optimal performance across enterprise environments – including support for manufacturing and Lab IT operations. 

Key Responsibilities

Automation and Scripting

• Develop and maintain PowerShell scripts to automate endpoint provisioning, system configurations, and routine tasks.
• Design and build deployment pipelines for efficient and scalable endpoint management.

Endpoint Management and Configuration

• Configure and manage Intune features such as Configuration Profiles, Compliance Policies, and BitLocker encryption.
• Deploy and manage applications across Windows, macOS, iOS, and Android platforms.
• Coordinate and execute the installation of client and department specific applications and systems.
• Create, manage, and maintain software deployment packages and operating systems.

Troubleshooting and Technical Expertise

• Diagnose and resolve complex end-user endpoint issues within an enterprise environment, especially after initial triage by other teams.
• Work on complex assignments requiring in-depth evaluation of diverse technical factors and procedures.

Project and Operational Management

• Manage projects with accountability for timelines, milestones, resources, budgets and documentation.
• Thrive in a fast-paced environment, demonstrating agility and adaptability to shifting business and functional demands.
• Participate in a follow-the-sun on-call rotation to support global operations.

Collaboration, Leadership and Mentorship

• Partner with IT and business project teams, including GIS End User Services, and Information Security.
• Improve internal and external working relationships and establish networks with key contacts beyond immediate areas of expertise.
• Train and mentor

Security and Compliance

• Collaborate on global security initiatives with cross-functional teams.
• Demonstrate a comprehensive understanding of endpoint security across laptops, desktops and mobile devices.

Reporting and Integration

• Experience in Service Now and its integration points for asset tracking, incident management and workflow automation.
• Enhance reporting capabilities to support compliance, performance monitoring and operational insights.

Requirements

• Proven experience managing SCCM and Microsoft Intune for endpoint provisioning, compliance and application deployment.
• Advanced proficiency in Active Directory and Azure, including OS provisioning, software packaging, image management, GPOs and configuration profiles.
• Strong experience with Windows Server administration and support.
• Extensive knowledge of developing and managing desktop operating systems (Windows and macOS).
• Proficiency in scripting languages such as PowerShell or Bash for automation and system configuration.
• Working knowledge of Jamf for Apple device management.
• Familiarity with AWS Workspaces, Microsoft Azure Services, Virtual Apps and Desktops.
• Understanding of AWS infrastructure and services for cloud native endpoint environments.
• Articulate and persuasive oral and written communications skills.
• Ability to work independently with minimal supervision while collaborating efficiently across teams.
• Experience working with Service Now and its integration points for asset tracking and incident management
• Exceptional analytical, strategic thinking and problem-solving abilities with strong focus on customer service.
• Capable of identifying and executing process improvement initiatives.
• Demonstrated ability to thrive in a fast-paced, agile environment, adapting quickly to changing business and functional demands.

Qualifications

• Microsoft SCCM and Intune subject matter experts.
• Bachelor’s degree in these related fields with 10+ years of experience in enterprise environments (Preferred)
• Strong understanding in automation design, process engineering, or solution architecture.
• Experience with endpoint management tools (e.g. workflow automation, scripting).
• Familiarity with enterprise architecture.
• Typically requires a minimum of 8 years of related experience with a Bachelor’s degree; or 6 years and a Master’s degree; or a PhD with 3 years experience; or equivalent experience.
• Preferred Certifications: Microsoft, AWS, Jamf, Service Now accreditation, ITIL Foundation

Work Authorization

Candidates must be authorized to work in the U.S. without sponsorship. This role does not offer visa sponsorship (H-1B, L-1, OPT/CPT) now or in the future. Refugee or asylee candidates with valid EAD/AP are welcome to apply.

#LI-ONSITE

The estimated base salary range for the Lead IT Engineer, End User Computing & Lab IT role based in the United States of America is: $118,200 - $177,200. Should the level or location of the role change during the hiring process, the applicable base pay range may be updated accordingly. Compensation decisions are dependent on several factors including, but not limited to, an individual’s qualifications, location where the role is to be performed, internal equity, and alignment with market data. Additionally, all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a wide range of benefits as innovative as our work, including access to genomics sequencing, family planning, health/dental/vision, retirement benefits, and paid time off.

We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information. Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws. Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process, please contact [email protected]. To learn more, visit: https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf. The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants. This role is not eligible for visa sponsorship.