Who We Are
Flagship Pioneering is a biotechnology company that invents and builds platform companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps. Those big leaps in human health and sustainability exponentially accelerate scientific progress in areas ranging from cancer detection and treatment to nature-positive agriculture.
What sets Flagship apart is our ability to advance biotechnology by uniting life science innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our scientific founders, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and transform for the benefit of people and planet.
Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.
Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies.
Job Summary
The Lead, Enterprise Applications & Service Management plays a critical role in ensuring Flagship Pioneering's enterprise applications effectively support and evolve with business needs. This position serves as a senior leader within the Enterprise Applications function and acts as a key partner to the Director of Enterprise Applications in driving operational excellence, service delivery maturity, and scalable support models across the application portfolio.
The role combines deep functional and technical expertise with strong operational leadership, vendor management, and stakeholder engagement capabilities. The Lead, Enterprise Applications & Service Management is responsible for overseeing the support, optimization, governance, and continuous improvement of critical enterprise applications while helping establish and mature enterprise-grade application operations practices.
This position will own key aspects of application service management, including MSP oversight, support governance, incident and change management processes, knowledge management, and operational reporting. The individual will serve as a trusted advisor to internal Business Relationship Managers (BRMs), IT leadership, and business stakeholders while helping scale the Enterprise Applications function through process standardization, automation, and operational excellence.
The ideal candidate has experience operating within a mature enterprise applications organization and has successfully led application support, service management, and vendor governance functions in complex enterprise environments.
Roles and Responsibilities
Service Operations & MSP Management
Application Management
Project & Implementation Support
Process Improvement & Documentation
Collaboration & Business Partnership
Education and Experience Requirements
We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.
We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship.
Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.
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The salary range for this role is $128,000 - $176,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Flagship Pioneering currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Flagship Pioneering's good faith estimate as of the date of publication and may be modified in the future.
Privacy Notice for Applicants: When you apply for a role at Flagship Pioneering or one of its portfolio companies, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact [email protected].
Skills Required
- Bachelor's degree in Information Systems, Computer Science, Business Administration, or related field (or equivalent experience).
- Minimum 7-10 years of experience supporting, administering, or leading enterprise applications in a complex enterprise environment.
- Demonstrated experience managing outsourced support providers, managed service providers (MSPs), or external application support vendors.
- Strong knowledge of IT Service Management (ITSM) practices and platforms, including Jira Service Management or equivalent tools.
- Working knowledge of ITIL principles and processes, including incident management, problem management, change management, CAB participation, service request management, and CMDB governance.
- Experience working within Agile and Scrum delivery frameworks.
- Experience leading enterprise software implementations, upgrades, and operational transitions.
- Experience developing operational metrics, service reporting, support models, and governance processes.
- Serve as subject matter expert for core enterprise applications (HCM, ATS, ERP, Procurement, CLM).
- Experience with enterprise platforms such as UKG, NetSuite, Salesforce, Coupa, Workato, or similar business-critical applications.
- Experience with application portfolio management, service operations, and continuous improvement initiatives.
- Prior experience in life sciences, biotechnology, healthcare, or similarly regulated and complex enterprise environments.
Flagship Pioneering Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Flagship Pioneering and has not been reviewed or approved by Flagship Pioneering.
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Fair & Transparent Compensation — Feedback suggests salary bands are visible for many Boston/Cambridge roles and pay is considered competitive for key scientific and leadership positions. Transparency in postings supports expectations that offers align with local biotech norms.
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Healthcare Strength — Feedback suggests medical, dental, vision, disability, life insurance, HSA options, and mental-health coverage are comprehensive and well-regarded. Multiple items are employer-verified, reinforcing confidence in core health benefits.
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Parental & Family Support — Feedback suggests maternity/paternity leave and family leave are offered at meaningful levels. These programs sit alongside paid holidays, sick days, and PTO to support family needs.
Flagship Pioneering Insights
What We Do
Flagship Pioneering conceives, creates, resources, and develops first-in-category life sciences companies to transform human health and sustainability. Since its launch in 2000, the firm has applied a unique, hypothesis-driven innovation process to originate and foster more than 100 scientific ventures, resulting in over $30 billion in aggregate value. To date, Flagship is backed by >$3 billion of aggregate capital commitments, of which over $1.5 billion has been deployed toward the founding and growth of its pioneering companies alongside >$10 billion of follow-on investments from other institutions. The current Flagship ecosystem includes Denali Therapeutics (NASDAQ: DNLI), Evelo Biosciences (NASDAQ: EVLO), Moderna Therapeutics (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), Seres Therapeutics (NASDAQ: MCRB), and Syros Pharmaceuticals (NASDAQ: SYRS).








