We are seeking a Prnicpal SAP S/4HANA Solution Architect to provide end-to-end architecture leadership and long-term ownership of the S/4HANA solution landscape. While the programme is approaching go-live in July, the primary focus of this role is to define and govern the target architecture, ensure architectural integrity across all workstreams, and shape the roadmap for ongoing evolution, optimisation, and innovation.
The Solution Architect will provide governance and design assurance across the SAP landscape (process, data, integration, security, and operations), supporting delivery through go-live and establishing a sustainable foundation for steady-state operations. This includes adherence to SAP Clean Core principles and enterprise standards, clear design decision-making, and a forward-looking architecture roadmap, with SAP BTP and SAP Integration Suite/CPI as key enabling components for integration and extensibility.
Responsibilities- Own and govern the end-to-end solution architecture for the S/4HANA programme, ensuring alignment across business processes, data, applications, integration, and security.
- Lead architecture governance and design authority forums; drive decisions, manage exceptions, and resolve cross-stream design gaps, risks, and technical debt.
- Validate end-to-end solution readiness ahead of go-live, including non-functional requirements (performance, resilience, monitoring, supportability) and operational handover into hypercare.
- Partner with programme leadership, functional leads, and delivery teams to support cutover planning, environment strategy, data migration validation, and integration sequencing.
- Engage senior stakeholders and provide architectural leadership across delivery phases; act as escalation point for complex, cross-functional technical issues.
- Ensure adherence to SAP Clean Core principles and the agreed extensibility strategy; protect the core while enabling continuous improvement.
- Define and govern BTP-based extensions and integration approaches (SAP Integration Suite/CPI, APIs, event-driven patterns), ensuring secure, scalable, and supportable designs.
- Oversee integration readiness (build quality, testing, monitoring/alerting, runbooks), ensuring all interfaces are production-ready and operable.
- Support rapid issue resolution during go-live and early life support, including integration failures, performance issues, and data inconsistencies, coordinating across SAP and non-SAP platforms.
- Define and transition to a sustainable target architecture and support model, including principles, standards, and a roadmap for post go-live optimisation and innovation.
Bachelor’s degree in computer science, information management, mathematics, statistics, biostatistics, business, or related field; advanced degree preferred
8-12 years of technology experience, preferably in Life Sciences or within a regulated environment
- Extensive experience as an SAP Solution Architect on S/4HANA programmes, owning end-to-end solution architecture and design governance.
- Proven experience in at least one end-to-end S/4HANA implementation approaching or at go-live, including hypercare/early life support.
- Strong understanding of core SAP processes and cross-functional integration (e.g., FI/CO, MM, SD, PP) and how they operate end to end.
- Solid understanding of integration patterns (APIs, messaging, event-driven), identity and access, and cloud/security considerations across SAP and non-SAP platforms.
- Hands-on experience with SAP BTP and SAP Integration Suite/CPI (design, monitoring, troubleshooting) in complex integration landscapes.
- Experience defining non-functional requirements and operational readiness (monitoring/alerting, logging, runbooks, support model) for production environments.
- Strong understanding of cutover planning, data migration validation, environment management, and release strategy.
- Experience working with SAP Activate (or comparable delivery methodology) and collaborating effectively across SI and internal teams.
- Strong stakeholder management, communication, and decision-making skills; able to balance speed of delivery with architectural integrity in time-critical environments.
Desired Skills
SAP certifications in S/4HANA, BTP, or Integration.
- Experience with RISE with SAP or S/4HANA Cloud.
- Knowledge of enterprise architecture frameworks (e.g., TOGAF).
Soft Skills
Excellent communication and stakeholder management skills.
Strong analytical and problem-solving abilities.
Proven leadership in complex, multi-stream delivery environments.
Delivery-focused with strong attention to detail
The annual base salary for this position ranges from $175,000 to $197,000. In addition, this position is eligible for an annual performance pay bonus. Exact compensation may vary based on skills, training, knowledge, and experience. Alkermes offers a competitive benefits package. Additional details can be found on our careers website: www.alkermes.com/careers#working-here
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About UsWhy join Team Alkermes?
Alkermes applies its decades of deep neuroscience expertise to develop medicines designed to help people living with complex and difficult-to-treat psychiatric and neurological disorders. A global biopharmaceutical company, headquartered in Ireland with U.S. locations in Massachusetts and Ohio, we seek to make a meaningful difference in the way people manage their diseases. We have a portfolio of proprietary commercial products for the treatment of alcohol dependence, opioid dependence, schizophrenia, bipolar I disorder and narcolepsy, and a pipeline of clinical and preclinical candidates in development for various psychiatric and neurological disorders.
We are proud to have been recognized as an employer of choice by many national organizations. In 2024 and 2025, we were certified as a Great Place to Work in the U.S. and named one of Massachusetts’ Top Places to Work by the Boston Globe, a Best Place to Work in Greater Cincinnati by the Cincinnati Business Courier and recognized as a Best Place to Work in BioPharma by Fortune Magazine.
Alkermes, Inc. is an equal employment opportunity employer and does not discriminate against any qualified applicant or employee because of race, creed, color, age, national origin, ancestry, religion, gender, sexual orientation, gender expression and identity, disability, genetic information, veteran status, military status, application for military service or any other characteristic protected by local, state or federal law. Alkermes also complies with all work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Alkermes is an E-Verify employer.
Skills Required
- Bachelor's degree in computer science, information management, mathematics, statistics, business, or related field
- 8-12 years of technology experience, preferably in Life Sciences or regulated environments
- Extensive experience as an SAP Solution Architect on S/4HANA programmes, owning end-to-end solution architecture and governance
- Experience in at least one end-to-end S/4HANA implementation approaching or at go-live, including hypercare/early life support
- Strong understanding of core SAP processes and cross-functional integration (FI/CO, MM, SD, PP)
- Hands-on experience with SAP BTP and SAP Integration Suite/CPI (design, monitoring, troubleshooting)
- Solid understanding of integration patterns (APIs, messaging, event-driven) and identity and access management
- Experience defining non-functional requirements and operational readiness (monitoring/alerting, logging, runbooks, support model)
- Experience with cutover planning, data migration validation, environment management, and release strategy
- Experience working with SAP Activate or comparable delivery methodology and collaborating with SIs and internal teams
- Strong stakeholder management, communication, and decision-making skills
- SAP certifications in S/4HANA, BTP, or Integration
- Experience with RISE with SAP or S/4HANA Cloud
- Knowledge of enterprise architecture frameworks (e.g., TOGAF)
What We Do
Alkermes focuses on the development of innovative medicines that seek to address unmet needs of people living with serious mental illness, addiction, and cancer. As a fully-integrated, global biopharmaceutical company, we apply our scientific expertise and proprietary technologies to develop products that are designed to make a meaningful difference in the way patients manage their disease. We are inspired by some of the most pressing public health challenges of our time to help advance innovation with the potential to improve treatment options and outcomes for patients. Beyond our important mission of developing medicines, we believe it is our responsibility to take a holistic approach as we seek to support patients, caregivers, and broader impacted communities. In this context we also work to help support and enhance the systems through which these complex diseases are treated. We are committed to patient engagement, disease education and awareness, and advocacy for important policies that support equitable access to quality treatment. Headquartered in Dublin, Ireland, we have an R&D center in Waltham, Massachusetts; a research and manufacturing facility in Athlone, Ireland; and a manufacturing facility in Wilmington, Ohio. See our Community Guidelines: https://www.alkermes.com/social-community-guidelines
