At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.
The PositionJob description
We are seeking a Principal Business Systems Analyst to help design, define, and scale technology solutions supporting commercial organizations across the US and global affiliates. You will operate at the intersection of business, product, data, and engineering, translating complex and ambiguous business problems into clear technical requirements and scalable solutions. You will partner with product managers, software engineers, data engineers, architects, data scientists, and commercial stakeholders across enterprise applications, data platforms, cloud services, analytics, APIs, and AI/GenAI capabilities. Hands-on software development is not required, but strong technical fluency is essential.
Description of the area
360 Insights Engineering builds and evolves commercial technology, data, analytics, and AI capabilities used across the US and global affiliates. The team partners across markets to identify where capabilities should be globally standardized versus locally configurable, while accounting for differences in processes, data, regulations, and operating models.
Job Responsibilities
- Partner with business and product leaders to understand complex commercial problems, lead discovery, challenge assumptions, and translate needs into clear functional and technical requirements.
- Define user stories, acceptance criteria, business rules, process flows, data requirements, system behaviors, and traceability from business objectives through implementation and validation.
- Decompose large, ambiguous initiatives into well-defined capabilities and engineering-ready requirements while proactively identifying scope, dependencies, edge cases, data issues, and operational risks.
- Serve as the primary bridge between business stakeholders and technical teams, participating confidently in discussions on system architecture, APIs, databases, cloud platforms, data pipelines, integrations, authentication/authorization, and AI services.
- Partner with architects and engineers to evaluate solution approaches, technical constraints, dependencies, and trade-offs, and review designs to ensure solutions satisfy business requirements and can scale across markets.
- Use SQL to investigate data, validate assumptions, troubleshoot issues, and support requirements definition, including relational models, joins, aggregations, data quality, and upstream/downstream dependencies.
- Translate analytical and reporting needs into clear data definitions, metrics, business rules, and transformations, partnering with data engineering and analytics teams on models, pipelines, reporting, and commercial analytics capabilities.
- Partner with product, engineering, and data science teams to identify AI/GenAI opportunities, translate them into measurable workflows, requirements, guardrails, and acceptance criteria, and ensure they solve real business problems.
- Apply working knowledge of LLMs, prompting, RAG, agents, model limitations, evaluation, and enterprise AI integration patterns when shaping AI-enabled solutions.
- Support products serving the US, Canada, Brazil, and other global affiliates by coordinating requirements across markets and balancing global standardization with appropriate local configuration.
- Work effectively across distributed teams, functions, and time zones, driving alignment and clear decisions in complex, cross-functional environments.
Qualifications
Education / Experience
- Experience as a Business Systems Analyst, Technical Business Analyst, Product Analyst, Systems Analyst, or similar technology-facing role, with demonstrated ability to translate ambiguous business problems into structured technical requirements.
- Strong hands-on proficiency with SQL and the ability to independently analyze and validate data.
- Strong experience with Jira and Confluence, including writing high-quality user stories, acceptance criteria, requirements, and technical documentation.
- Experience partnering directly with software engineers, data engineers, architects, product managers, data scientists, and business stakeholders.
- Strong analytical problem-solving, written and verbal communication, ownership, and continuous improvement mindset.
- Experience operating across complex, distributed, or global organizations and managing multiple priorities and dependencies.
Technical Skills
- Strong understanding of REST APIs, system integrations, relational databases and data models, cloud-based applications and services, distributed-system fundamentals, authentication/authorization, data pipelines, and analytics platforms.
- Ability to read and reason about architecture diagrams, API specifications, data models, and system workflows.
- Working knowledge of AWS, Azure, or GCP and modern cloud architecture patterns.
- Working knowledge of AI/GenAI concepts including LLMs, prompting, RAG, agents, model evaluation, model limitations, guardrails, and enterprise AI integration patterns.
- Ability to use GenAI tools to accelerate requirements analysis, research, documentation, data exploration, process mapping, solution design, and lightweight prototyping while critically validating generated outputs.
- Ability to recognize when AI should and should not be used, particularly with sensitive enterprise data, regulated information, and business-critical decisions.
- Familiarity with commercial technology and data domains such as CRM, customer engagement, field operations, sales analytics, targeting/segmentation, marketing technology, or commercial data platforms.
Additional Qualifications
- Experience in commercial life sciences, pharmaceuticals, biotechnology, healthcare technology, or another regulated industry is strongly preferred.
- Experience supporting technology products across multiple countries or global business units is preferred.
- Experience defining or delivering AI/GenAI-enabled products, including enterprise LLM, RAG, agent, or AI evaluation use cases, is preferred.
- Experience with large-scale analytical platforms or complex enterprise datasets is preferred.
- Ability to create lightweight prototypes, workflow concepts, diagrams, analyses, and proof-of-concepts using AI-enabled tools where appropriate.
- Continuously explores emerging AI capabilities and incorporates useful tools and techniques into day-to-day work.
- Experience in highly scaled technology, retail, or digital organizations such as Google, Meta, Amazon, or comparable companies is valued where candidates demonstrate strong product, data, and systems thinking.
#Hyderabad2026
Who we are
A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.
Let’s build a healthier future, together.
Roche is an Equal Opportunity Employer.
Skills Required
- Experience as a Business Systems Analyst, Technical Business Analyst, Product Analyst, Systems Analyst, or similar technology-facing professional
- Experience translating ambiguous business problems into structured technical requirements
- Strong hands-on proficiency with SQL and ability to independently analyze and validate data
- Strong experience with Jira and Confluence, including user stories, acceptance criteria, requirements, and technical documentation
- Experience partnering with software engineers, data engineers, architects, product managers, data scientists, and business stakeholders
- Strong analytical problem-solving, written and verbal communication, ownership, and continuous improvement skills
- Experience working across complex, distributed, or global organizations and managing multiple priorities and dependencies
- Understanding of REST APIs, system integrations, relational databases, data models, cloud applications, distributed systems, authentication, authorization, data pipelines, and analytics platforms
- Ability to interpret architecture diagrams, API specifications, data models, and system workflows
- Working knowledge of AWS, Azure, or GCP and modern cloud architecture patterns
- Working knowledge of AI/GenAI concepts, including LLMs, prompting, RAG, agents, model evaluation, limitations, guardrails, and enterprise integration patterns
- Ability to use and critically validate GenAI tools for requirements analysis, documentation, data exploration, process mapping, solution design, and prototyping
- Ability to assess appropriate use of AI with sensitive enterprise data, regulated information, and business-critical decisions
- Familiarity with commercial technology and data domains such as CRM, customer engagement, sales analytics, targeting, segmentation, marketing technology, or commercial data platforms
- Experience in commercial life sciences, pharmaceuticals, biotechnology, healthcare technology, or another regulated industry
- Experience supporting technology products across multiple countries or global business units
- Experience defining or delivering AI/GenAI-enabled products, including enterprise LLM, RAG, agent, or AI evaluation use cases
- Experience with large-scale analytical platforms or complex enterprise datasets
- Ability to create lightweight prototypes, workflow concepts, diagrams, analyses, and proofs of concept using AI-enabled tools
- Experience in highly scaled technology, retail, or digital organizations such as Google, Meta, Amazon, or comparable companies
Roche Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Roche and has not been reviewed or approved by Roche.
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Retirement Support — U.S. materials describe a 401(k) with both matching and an additional company contribution, supported by formal plan documents and true‑up features. This structure is positioned as a standout element of the total package, particularly at Genentech.
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Leave & Time Off Breadth — Time‑off provisions include substantial vacation, a year‑end shutdown, and a paid six‑week sabbatical after six years. These elements indicate a recharge‑oriented approach within the U.S. offering.
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Healthcare Strength — Company materials emphasize comprehensive medical, dental, vision, and mental‑health resources alongside well‑being programs. Benefits pages consistently highlight breadth across core health coverage elements.
Roche Insights
What We Do
Roche is a global pioneer in pharmaceuticals and diagnostics focused on advancing science to improve people’s lives. The combined strengths of pharmaceuticals and diagnostics under one roof have made Roche the leader in personalised healthcare – a strategy that aims to fit the right treatment to each patient in the best way possible. Roche is the world’s largest biotech company, with truly differentiated medicines in oncology, immunology, infectious diseases, ophthalmology and diseases of the central nervous system. Roche is also the world leader in in vitro diagnostics and tissue-based cancer diagnostics, and a frontrunner in diabetes management. Founded in 1896, Roche continues to search for better ways to prevent, diagnose and treat diseases and make a sustainable contribution to society. The company also aims to improve patient access to medical innovations by working with all relevant stakeholders. Thirty medicines developed by Roche are included in the World Health Organization Model Lists of Essential Medicines, among them life-saving antibiotics, antimalarials and cancer medicines. Roche has been recognised as the Group Leader in sustainability within the Pharmaceuticals, Biotechnology & Life Sciences Industry ten years in a row by the Dow Jones Sustainability Indices (DJSI).








