The Information Security Engineer independently implements, administers, and supports security solutions across enterprise systems. This role applies specialized technical knowledge to analyze security posture, design controls aligned with business requirements, and protect organizational systems and data.
Depending on the area of focus, the Information Security Engineer may support a variety of application protection initiatives and operations related to Vulnerability and Exposure Management and Secure Cloud & Software Delivery. Examples of such activities include the following:
- Configure and operate vulnerability scanning tools; troubleshooting anomalies.
- Implement and maintain integrations between tools supported within and outside the department to enable automated workflows and reporting.
- Coordinate exception management workflows related to vulnerability and application protection policies.
- Coordinate and oversee Attack Surface Management activities, including the use of advanced tooling for digital asset discovery and protection.
- Partner with cloud engineering teams to embed security within the container lifecycle, support container vulnerability management, and integrate security controls into cloud hosting platforms.
- Implement and support software supply chain security capabilities.
- Administer Infrastructure as Code (IaC) and Policy as Code (PaC) tools, which enforce logic-based policy decisions.
This vacancy is not eligible for sponsorship/ we will not sponsor or transfer visas for this position. Also, Mayo Clinic DOES NOT participate in the F-1 STEM OPT extension program.
QualificationsBachelor's degree and four (4) years experience in the information security field required, OR Associates degree and 6 years' experience in the information security field. Pertinent fields of study include Computer Science, Information Systems, Engineering or related field.
Master's Degree in applicable field and two (2) years experience preferred. Pertinent fields of study include Computer Science, Information Systems, Engineering or related field.
One or more of the following certifications (or equivalent) are required at time of hire or must be obtained within two years of hire: CISSP, CISM, GSEC, OSCP.
Preferred Qualifications
- Systems administration, systems engineering, or security experience across Windows, Linux, network, cloud, endpoint, or containerized environments.
- Experience supporting or troubleshooting security or technology platforms, including vulnerability management or application security tools.
- Familiarity with vulnerability and exposure management, containers, CI/CD, software supply chain security, and cloud security concepts.
- Familiarity with scripting or automation using PowerShell, Python, Bash, or similar technologies, with strong troubleshooting and collaboration skills.
Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
- Medical: Multiple plan options.
- Dental: Delta Dental or reimbursement account for flexible coverage.
- Vision: Affordable plan with national network.
- Pre-Tax Savings: HSA and FSAs for eligible expenses.
- Retirement: Competitive retirement package to secure your future.
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law". Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.
Skills Required
- Bachelor's degree in Computer Science, Information Systems, Engineering, or a related field, plus four years of information security experience
- Associate's degree plus six years of information security experience
- One or more of CISSP, CISM, GSEC, OSCP, or equivalent certification at hire or within two years
- Master's degree in an applicable field plus two years of experience
- Systems administration, systems engineering, or security experience across Windows, Linux, network, cloud, endpoint, or containerized environments
- Experience supporting or troubleshooting security or technology platforms, including vulnerability management or application security tools
- Familiarity with vulnerability and exposure management, containers, CI/CD, software supply chain security, and cloud security
- Familiarity with scripting or automation using PowerShell, Python, Bash, or similar technologies
- Strong troubleshooting and collaboration skills
Mayo Clinic Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Mayo Clinic and has not been reviewed or approved by Mayo Clinic.
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Retirement Support — A no-cost pension plus an employer-matched 403(b)/401(k) is positioned as a standout differentiator, offering strong long-term financial security. Feedback suggests this retirement combination elevates overall total rewards even when base pay is moderate.
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Healthcare Strength — Expanded medical networks, enhanced fertility coverage, and employer absorption of a plan year’s premium increases point to robust healthcare offerings. Feedback suggests annual updates maintain breadth and competitiveness of coverage.
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Parental & Family Support — Adoption assistance, dependent scholarships, child and elder-care resources, and EAP services provide meaningful family-oriented support. Feedback suggests these programs add tangible value beyond salary alone.
Mayo Clinic Insights
What We Do
Mayo Clinic is the first and largest integrated, not-for-profit medical group practice in the world. Doctors from every medical specialty work together to care for patients, joined by common systems and a philosophy of "the needs of the patient come first." More than 3,800 physicians and scientists and 50,900 allied health staff work at Mayo Clinic, which has sites in Rochester, Minn., Jacksonville, Fla., and Scottsdale/Phoenix, Ariz. Mayo Clinic also serves over 70 communities through Mayo Clinic Health System with locations in MN, IA, and WI. Collectively, these locations care for more than 1 million people each year.
