We are currently recruiting for a HT-Analytical Senior Scientist, to join our Analytical Sciences team based in Alderley Park.
Role: HT-Analytical Senior Scientist
Role Type: Permanent
Department: Analytical Sciences
Responsible for: Junior team members, as may be assigned
Working hours: Full time, 9am-5pm, Monday – Friday (37.5 hours per week)
Location: Alderley Park, Macclesfield, SK10 4TG
Our Company
Cyprotex is part of the Evotec Group, a global leader in research. With state-of-the-art facilities and technical expertise, we provide innovative and bespoke assurance tailored to each of our client’s needs. Cyprotex specialises in in-vitro and in-silico ADME-Tox services. This includes in vitro ADME screening to support discovery projects, regulatory in vitro ADME and DDI studies during preclinical and clinical development, specialist mechanistic in vitro human and animal toxicity models (e.g., 3D models and MEA electrophysiology) and PBPK/QSAR modelling expertise. As well as supporting clients directly, we have a strong focus on R&D.
Our Alderley Park site is set in the heart of Cheshire surrounded by a stunning 400-acre estate, open green spaces, and sweeping viewpoints, all within easy reach of Merseyside and Greater Manchester, Staffordshire, Derbyshire and Shropshire. Easy access to public transport.
Role and Responsibilities
Plan and conduct both routine and Analytical Sciences assays including MS/MS compound optimisation and LC method optimisation for high volumes of compounds using automated tools and established processes
To be a senior point of contact, for the team and study managers, for operational and scientific support across all routine assays, including problem solving, data analysis and data interpretation.
To effectively plan and communicate assay schedule within the team and cross-functional groups.
To drive and support assay development and validation.
To collaborate with scientists and regularly present findings to the group.
To ensure that all errors and erroneous results are reported to your supervisor with minimal delay.
To keep up to date with relevant scientific advances and regulatory guidelines in the field of Analytical Sciences.
To ensure all laboratory equipment and work areas are clean and in proper working order on completion of assigned tasks.
To ensure accurate and complete documentation of all activities as required by relevant SOPs and Quality policies.
To keep up to date with future technologies/instrumentation establishing benefits and implementation for HT-Analytical
Skills & Competencies (essential)
Minimum BSc in relevant scientific discipline covering chemistry with experience of working within industry
Produce accurate documentation and report all analytical activities and results in a clear and coherent manner, maintaining the highest standards of quality and compliance, with a high level of attention to detail and the ability to work without close supervision.
Highly motivated team player with a high level of dedication.
Plan, schedule and carry out your work effectively for successful project completion.
Experience in working with LC-MS/MS techniques in support of pre-clinical small/large molecule assays.
Experience with MassLynx™, Analyst™ or other Mass Spectrometry data-acquisition software packages.
A wider knowledge of analytical support in drug discovery/development.
A knowledge of DMPK/ADME assays within drug discovery.
The ability to perform routine maintenance/troubleshoot on LC-MS/MS equipment
People
Coach, mentor and line manage other members of the team meetings, regular 1 to1 discussions and ad hoc interactions.
Additional Benefits
What we can offer you in return
We offer a competitive salary and benefits package.
Pension on completion (but not subject to) of your 3-month probationary period. Contributions 6% for employees (salary sacrifice) and 6% for the employer. The employee can opt to increase their contribution and the employer will match the increase up to a maximum of 7.5%.
25 days holiday plus bank holidays and additional length of service days awarded on the anniversary, up to a maximum of 30 days.
Private health insurance with BUPA for the employee and their partner/family under the company scheme.
Private dental cover, on completion (but not subject to) of your 3-month probationary period.
Wellbeing support 24/7 and counselling services
Permanent health insurance provides 75% of the base salary after the qualifying period.
Eligibility to participate in the Company Bonus Scheme. This is a discretionary benefit.
Career progression within the company, we have excellent training and support and continuing professional development opportunities.
Cycle-to-work scheme
Refer a friend scheme, team and annual events, recognition awards and many more!
Onsite Facilities
The company pays for secure onsite parking.
Restaurant, Café, and a Gastro pub
Gym and workout studio, running, walking, and cycling routes.
Good public transport links with the shuttle bus service.
***If you are interested in this position please upload your most up to date CV & covering letter through our career site***
FR : Dans le cadre de sa politique Diversité, Evotec étudie, à compétences égales, toutes les candidatures dont celles des personnes en situation de handicap.
ENG : In the frame of our Diversity policy, Evotec considers, with equal competences, all applications including people with disabilities.
Skills Required
- Minimum BSc in relevant scientific discipline covering chemistry with experience of working within industry
- Experience in working with LC-MS/MS techniques in support of pre-clinical small/large molecule assays
- Experience with MassLynx™, Analyst™ or other Mass Spectrometry data-acquisition software packages
- A wider knowledge of analytical support in drug discovery/development
- A knowledge of DMPK/ADME assays within drug discovery
- The ability to perform routine maintenance/troubleshoot on LC-MS/MS equipment
What We Do
Evotec is a biotechnology company that is committed to advancing drug discovery and development. Through flexible business models, we collaborate with pharmaceutical companies, biotechs, foundations, and government agencies on a substantial scale. We believe that by working together, we can make a difference in the lives of patients. Our Pipeline Co-Creation model represents our adaptable, multi-modality, fully integrated end-to-end approach to drive collaborations and services across all phases of drug discovery and development – from discovery of novel targets to achieving Proof of Concept in the clinic and into commercial manufacturing. We aspire to contribute data-driven disease understanding and early disease relevance in humans to bring the probability of success up. We select the right modality, which is then propelled forward on our platforms by our passionate people striving for the fastest and most effective ways towards patient impact. This is enabled by convergence of human ingenuity with data and AI. We also offer specific solutions, products, and CRO/CDMO-like services, always in support of the Biopharma R&D innovator. Our more than 4,000 scientists work closely with numerous partners concurrently, delivering fully integrated research and development portfolios or individual projects with the highest quality standards and efficiency, coupled with great science, passion, engagement, and communication.
