At Caris, we understand that cancer is an ugly word—a word no one wants to hear, but one that connects us all. That’s why we’re not just transforming cancer care—we’re changing lives.
We introduced precision medicine to the world and built an industry around the idea that every patient deserves answers as unique as their DNA. Backed by cutting-edge molecular science and AI, we ask ourselves every day: “What would I do if this patient were my mom?” That question drives everything we do.
But our mission doesn’t stop with cancer. We're pushing the frontiers of medicine and leading a revolution in healthcare—driven by innovation, compassion, and purpose.
Join us in our mission to improve the human condition across multiple diseases. If you're passionate about meaningful work and want to be part of something bigger than yourself, Caris is where your impact begins.
Position Summary
An HPC Systems Administrator is responsible for managing and maintaining high-performance computing (HPC) systems, including hardware, software, and network infrastructure, ensuring optimal performance and stability for computationally intensive research or business applications, often involving tasks like installing and configuring specialized software, monitoring system health, optimizing job scheduling, and troubleshooting complex technical issues related to large-scale computing environments.
Job Responsibilities
System Installation and Configuration:
Installing and configuring HPC hardware (clusters, servers, storage)
Deploying and configuring HPC software (operating systems, job schedulers, parallel programming environments)
Setting up network infrastructure for high-speed data transfer
Performance Optimization:
Monitoring system health and resource utilization
Analyzing job performance and identifying bottlenecks
Optimizing job scheduling algorithms to maximize throughput
Tuning system parameters for optimal performance
User Support:
Providing technical support to HPC users on system access, job submission, and troubleshooting
Developing user documentation and training materials
Security Management:
Implementing security policies and procedures for HPC systems
Managing user access and permissions
Monitoring for potential security threats
Backup and Disaster Recovery:
Implementing data backup strategies for HPC systems
Testing and maintaining disaster recovery plans
Hardware Maintenance:
Coordinating hardware repairs and upgrades with vendors
Required Qualifications
Bachelor's degree in Computer Science, Information Technology, Engineering, or a related technical field, or three (3) years of directly related Linux systems administration or HPC infrastructure experience in lieu of a bachelor's degree.
Minimum of 3 years of Linux system administration experience in an enterprise or HPC environment.
Minimum of 2 years administering or supporting High Performance Computing (HPC) infrastructure.
Minimum of 2 years of experience with HPC job schedulers such as IBM LSF
Minimum of 2 years of experience administering parallel file systems, such as IBM Spectrum Scale (GPFS), Lustre, or BeeGFS.
Minimum of 2 years supporting enterprise storage solutions, such as NetApp E-Series or similar SAN storage platforms.
Experience supporting high speed networking technologies, including InfiniBand or equivalent low latency networking.
Experience troubleshooting Linux operating systems, networking, storage, and distributed computing environments.
Experience with shell scripting (Bash) and/or Python for system administration and automation.
Experience installing, configuring, and maintaining enterprise server hardware in a data center environment.
Ability to participate in an on-call rotation and respond to after-hours production incidents.
Ability to lift and install server, storage, and networking equipment as required.
Proficient in Microsoft Office Suite, specifically Word, Excel, Outlook, and general working knowledge of Internet for business use
Preferred Qualifications
Basic understanding of Linux operating system.
Expertise in HPC software and hardware systems like IBM Spectra Scale, NetApp E-Series storage, Nvidia InfiniBand and job schedulers (e.g., LSF, Slurm)
Knowledge of network administration and high-performance networking protocols
Experience with system monitoring and performance analysis tools
Excellent problem-solving and troubleshooting abilities
Physical Demands
Ability to lift, move and install HPC data center hardware and supplies.
Standing for extended periods while performing data center related tasks.
Training
All job-specific, safety, and compliance training will be assigned based on the job functions associated with this employee.
Other
This position requires periodic travel and some evenings, weekends, and/or holidays.
Job may require after-hours response to emergency issues.
Periodically scheduled on-call may require after-hours response for technical emergencies not explicitly related to assigned job responsibilities
Conditions of Employment: Individual must successfully complete pre-employment process, which includes criminal background check, drug screening, credit check ( applicable for certain positions) and reference verification.
This job description reflects management’s assignment of essential functions. Nothing in this job description restricts management’s right to assign or reassign duties and responsibilities to this job at any time.
Caris Life Sciences is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, gender, gender identity, sexual orientation, age, status as a protected veteran, among other things, or status as a qualified individual with disability.
Skills Required
- Bachelor's degree in Computer Science, Information Technology, Engineering, or related field, or three years of directly related Linux systems administration or HPC infrastructure experience
- Minimum of 3 years of Linux system administration experience in an enterprise or HPC environment
- Minimum of 2 years administering or supporting High Performance Computing (HPC) infrastructure
- Minimum of 2 years of experience with HPC job schedulers such as IBM LSF
- Minimum of 2 years experience administering parallel file systems (IBM Spectrum Scale (GPFS), Lustre, or BeeGFS)
- Minimum of 2 years supporting enterprise storage solutions such as NetApp E-Series or similar SAN storage platforms
- Experience supporting high speed networking technologies, including InfiniBand or equivalent low latency networking
- Experience troubleshooting Linux operating systems, networking, storage, and distributed computing environments
- Experience with shell scripting (Bash) and/or Python for system administration and automation
- Experience installing, configuring, and maintaining enterprise server hardware in a data center environment
- Ability to participate in an on-call rotation and respond to after-hours production incidents
- Ability to lift and install server, storage, and networking equipment as required
- Proficient in Microsoft Office Suite, specifically Word, Excel, Outlook
- Basic understanding of Linux operating system
- Expertise in HPC software and hardware systems like IBM Spectra Scale, NetApp E-Series storage, Nvidia InfiniBand and job schedulers (LSF, Slurm)
- Knowledge of network administration and high-performance networking protocols
- Experience with system monitoring and performance analysis tools
- Excellent problem-solving and troubleshooting abilities
Caris Life Sciences Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Caris Life Sciences and has not been reviewed or approved by Caris Life Sciences.
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Fair & Transparent Compensation — Pay is considered competitive or fair across many roles and locations. Shift differentials and overtime opportunities in certain lab roles can further boost take‑home pay.
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Healthcare Strength — Medical coverage is described as strong, with the employer covering the majority of premiums and health insurance frequently cited positively. Day‑one eligibility and company‑paid short‑ and long‑term disability reinforce core health protections.
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Retirement Support — A 401(k) with immediate vesting and a defined employer match supports long‑term savings. Plan details are presented clearly in benefits materials.
Caris Life Sciences Insights
What We Do
Caris Life Sciences was founded in 2008 with a simple but powerful purpose – to help improve the lives of as many people as possible. With transformative technologies informed by massive amounts of big data, we are revolutionizing healthcare to provide physicians and patients with the highest quality information about their disease – from detecting it early and determining how best to treat it, to developing the next wave of novel therapies.








